Psoriatic arthritis in reykjavik, iceland: prevalence, demographics, and disease course

2.50
Hdl Handle:
http://hdl.handle.net/2336/14434
Title:
Psoriatic arthritis in reykjavik, iceland: prevalence, demographics, and disease course
Authors:
Love, Thorvardur Jon; Gudbjornsson, Bjorn; Gudjonsson, Johann Eli; Valdimarsson, Helgi
Citation:
J. Rheumatol. 2007, 34(10):2082-8
Issue Date:
1-Oct-2007
Abstract:
OBJECTIVE: To determine the prevalence, demographics, and course of psoriatic arthritis (PsA) in the Reykjavik area of Iceland. METHODSl In total 220 patients >/= 18 years of age living in the Reykjavik area of Iceland were located in a community registry of psoriatic patients and in hospital records. Of these, 156 (71%) were interviewed and examined for verification of skin and joint disease according to published criteria. RESULTS: Prevalence of PsA in the adult population was estimated to be 164 per 100,000 (95% CI 143-187), adjusted to 139 per 100,000 (95% CI 112-169) after exclusion of 25 individuals. The female to male ratio was close to 2:1. The mean age at skin disease onset was 23 years, with significantly earlier onset in women (age 20 yrs in women vs 26 yrs in men; p = 0.01), but there was no significant difference for age at the time of onset of joint disease. Mean duration of PsA was 20 years. Oligoarthritis was the most common (44%), followed by polyarthritis (31%), enthesitis (8%), and inflammatory back pain (7%). According to patients' recall of clinical features at onset, 78 patients (60%) had changed categories of PsA at the time of the study, most frequently from polyarthritis to oligoarthritis (48%), followed by oligoarthritis to polyarthritis (36%). These changes seemed independent of use of disease modifying drugs, which 54% had received. CONCLUSION: PsA in Reykjavik, Iceland, has a prevalence of at least 0.14% and is strikingly more common in women. The majority of patients reported a change in the pattern of affected joints during the course of their disease.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Link field
Additional Links:
http://www.jrheum.com/subscribers/07/10/2082.html

Full metadata record

DC FieldValue Language
dc.contributor.authorLove, Thorvardur Jon-
dc.contributor.authorGudbjornsson, Bjorn-
dc.contributor.authorGudjonsson, Johann Eli-
dc.contributor.authorValdimarsson, Helgi-
dc.date.accessioned2007-11-01T12:56:10Z-
dc.date.available2007-11-01T12:56:10Z-
dc.date.issued2007-10-01-
dc.date.submitted2007-11-01-
dc.identifier.citationJ. Rheumatol. 2007, 34(10):2082-8en
dc.identifier.issn0315-162X-
dc.identifier.pmid17696270-
dc.identifier.urihttp://hdl.handle.net/2336/14434-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Link fielden
dc.description.abstractOBJECTIVE: To determine the prevalence, demographics, and course of psoriatic arthritis (PsA) in the Reykjavik area of Iceland. METHODSl In total 220 patients >/= 18 years of age living in the Reykjavik area of Iceland were located in a community registry of psoriatic patients and in hospital records. Of these, 156 (71%) were interviewed and examined for verification of skin and joint disease according to published criteria. RESULTS: Prevalence of PsA in the adult population was estimated to be 164 per 100,000 (95% CI 143-187), adjusted to 139 per 100,000 (95% CI 112-169) after exclusion of 25 individuals. The female to male ratio was close to 2:1. The mean age at skin disease onset was 23 years, with significantly earlier onset in women (age 20 yrs in women vs 26 yrs in men; p = 0.01), but there was no significant difference for age at the time of onset of joint disease. Mean duration of PsA was 20 years. Oligoarthritis was the most common (44%), followed by polyarthritis (31%), enthesitis (8%), and inflammatory back pain (7%). According to patients' recall of clinical features at onset, 78 patients (60%) had changed categories of PsA at the time of the study, most frequently from polyarthritis to oligoarthritis (48%), followed by oligoarthritis to polyarthritis (36%). These changes seemed independent of use of disease modifying drugs, which 54% had received. CONCLUSION: PsA in Reykjavik, Iceland, has a prevalence of at least 0.14% and is strikingly more common in women. The majority of patients reported a change in the pattern of affected joints during the course of their disease.en
dc.language.isoenen
dc.publisherJournal Of Rheumatology Publishing Coen
dc.relation.urlhttp://www.jrheum.com/subscribers/07/10/2082.htmlen
dc.subject.meshPubMed - in processen
dc.subject.meshArthritis, Psoriaticen
dc.subject.meshPrevalenceen
dc.titlePsoriatic arthritis in reykjavik, iceland: prevalence, demographics, and disease courseen
dc.typeArticleen
dc.identifier.journalJournal of rheumatologyen
dc.format.digYES-

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