Paternity change and the recurrence risk in familial hypertensive disorder in pregnancy

2.50
Hdl Handle:
http://hdl.handle.net/2336/14465
Title:
Paternity change and the recurrence risk in familial hypertensive disorder in pregnancy
Authors:
Hjartardottir, Sigrun; Leifsson, Björn G; Geirsson, Reynir T; Steinthorsdottir, Valgerdur
Citation:
Hypertens Pregnancy 2004, 23(2):219-25
Issue Date:
20-Jun-2004
Abstract:
OBJECTIVE: To investigate if there is an increased risk for recurrence of hypertensive disorder in pregnancy with a new partner and whether this is affected by maternal age and the interbirth interval through use of familial material. METHODS: Data on 614 multiparous women, with confirmed de novo hypertensive disorder in a first pregnancy, were used to assess the effect of paternity and interbirth interval on recurrence of hypertensive disorders. RESULTS: There were 121 women (19.7%) who had changed partner. Recurrent hypertension occurred in 318 women (64.5%) with the same partner and in 75 women (62%) with a new partner. The odds ratio (OR) for recurrence with the same partner was 1.115 (95% CI 0.739-1.680) and with a new partner 0.897 (95% CI 0.595-1.353). The mean interbirth interval was longer for women with recurrent hypertension (4.9 vs. 4.0 years, p = 0.0002). The OR for developing recurrent hypertensive disorder was 1.154 (95% CI 1.049-1.269) for every interval year with the same partner and 1.145 (95% CI 0.958-1.368) with a new partner after correction for maternal age. CONCLUSION: In women with a positive family history and previous hypertension in pregnancy, change of paternity does not influence the risk of recurrence. Increasing interbirth interval may account for a 15% recurrence risk for each year, independent of maternal age. There was no indication that a change of partner conferred any influence on the recurrence risk that is not explained with birth interval or age.
Description:
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Full metadata record

DC FieldValue Language
dc.contributor.authorHjartardottir, Sigrun-
dc.contributor.authorLeifsson, Björn G-
dc.contributor.authorGeirsson, Reynir T-
dc.contributor.authorSteinthorsdottir, Valgerdur-
dc.date.accessioned2007-11-05T12:59:36Z-
dc.date.available2007-11-05T12:59:36Z-
dc.date.issued2004-06-20-
dc.date.submitted2007-11-05-
dc.identifier.citationHypertens Pregnancy 2004, 23(2):219-25en
dc.identifier.issn1064-1955-
dc.identifier.pmid15369654-
dc.identifier.doi10.1081/PRG-120037889-
dc.identifier.urihttp://hdl.handle.net/2336/14465-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractOBJECTIVE: To investigate if there is an increased risk for recurrence of hypertensive disorder in pregnancy with a new partner and whether this is affected by maternal age and the interbirth interval through use of familial material. METHODS: Data on 614 multiparous women, with confirmed de novo hypertensive disorder in a first pregnancy, were used to assess the effect of paternity and interbirth interval on recurrence of hypertensive disorders. RESULTS: There were 121 women (19.7%) who had changed partner. Recurrent hypertension occurred in 318 women (64.5%) with the same partner and in 75 women (62%) with a new partner. The odds ratio (OR) for recurrence with the same partner was 1.115 (95% CI 0.739-1.680) and with a new partner 0.897 (95% CI 0.595-1.353). The mean interbirth interval was longer for women with recurrent hypertension (4.9 vs. 4.0 years, p = 0.0002). The OR for developing recurrent hypertensive disorder was 1.154 (95% CI 1.049-1.269) for every interval year with the same partner and 1.145 (95% CI 0.958-1.368) with a new partner after correction for maternal age. CONCLUSION: In women with a positive family history and previous hypertension in pregnancy, change of paternity does not influence the risk of recurrence. Increasing interbirth interval may account for a 15% recurrence risk for each year, independent of maternal age. There was no indication that a change of partner conferred any influence on the recurrence risk that is not explained with birth interval or age.en
dc.language.isoenen
dc.publisherTaylor & Francisen
dc.relation.urlhttp://search.ebscohost.com/login.aspx?direct=true&db=aph&AN=13872081&site=ehost-liveen
dc.subject.meshHypertensionen
dc.subject.meshIceland/epidemiologyen
dc.subject.meshMaternal Ageen
dc.subject.meshMaternal Welfareen
dc.subject.meshPaternityen
dc.subject.meshPre-Eclampsiaen
dc.subject.meshPregnancyen
dc.subject.meshPregnancy Complications, Cardiovascularen
dc.subject.meshRecurrenceen
dc.subject.meshRisk Factorsen
dc.subject.meshStatisticsen
dc.titlePaternity change and the recurrence risk in familial hypertensive disorder in pregnancyen
dc.typeArticleen
dc.format.digYES-

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