2.50
Hdl Handle:
http://hdl.handle.net/2336/14509
Title:
Changes in muscle compartment pressure after cardiopulmonary bypass
Authors:
Simonardottir, Liney; Torfason, Bjarni; Stefansson, Einar; Magnusson, Jonas
Citation:
Perfusion 2006, 21(3):157-63
Issue Date:
1-May-2006
Abstract:
PURPOSE: Hemodilution and inflammation lead to edema and increased muscle compartment pressure after cardiac surgery. The aim of this study was to find whether muscle compartment pressure was affected by the addition of albumin and mannitol to the pump prime, heparin coating or leukocyte depletion. Additionally, we studied the relationship between intraocular pressure and lower leg muscle compartment pressure. Edema during and following cardiac surgery is due to hemodynamic, osmotic and inflammatory changes, according to Starling's Law. We attempted to influence the osmotic balance and reduce the inflammatory response in order to reduce the edema. METHODS: Thirty-six patients who underwent cardiac surgery were randomly allocated into four groups. Group A received albumin and mannitol into the pump prime. Group B had an, heparin-coated perfusion system, Group C had a leukocyte-depletion arterial line filter and Group D was the control group, where intraocular pressure was also measured. RESULTS: Lower leg muscle compartment pressure increased significantly during and after cardiac surgery in all groups, but this increase was significantly less in Group A than in the control group 24 h after surgery. No correlation was found between muscular compartment pressure and intraocular pressure. The intraocular pressure profile is different from the muscular compartment pressure and recovers much faster. CONCLUSION: Lower leg muscle compartment pressure and intraocular pressure behave differently during and after cardiac surgery. Albumin and mannitol added to the pump prime decreases muscle compartment pressure after cardiac surgery.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://search.ebscohost.com/login.aspx?direct=true&db=aph&AN=20619048&site=ehost-live

Full metadata record

DC FieldValue Language
dc.contributor.authorSimonardottir, Liney-
dc.contributor.authorTorfason, Bjarni-
dc.contributor.authorStefansson, Einar-
dc.contributor.authorMagnusson, Jonas-
dc.date.accessioned2007-11-08T15:06:45Z-
dc.date.available2007-11-08T15:06:45Z-
dc.date.issued2006-05-01-
dc.date.submitted2007-11-08-
dc.identifier.citationPerfusion 2006, 21(3):157-63en
dc.identifier.issn0267-6591-
dc.identifier.pmid16817288-
dc.identifier.doi10.1191/0267659106pf861oa-
dc.identifier.urihttp://hdl.handle.net/2336/14509-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractPURPOSE: Hemodilution and inflammation lead to edema and increased muscle compartment pressure after cardiac surgery. The aim of this study was to find whether muscle compartment pressure was affected by the addition of albumin and mannitol to the pump prime, heparin coating or leukocyte depletion. Additionally, we studied the relationship between intraocular pressure and lower leg muscle compartment pressure. Edema during and following cardiac surgery is due to hemodynamic, osmotic and inflammatory changes, according to Starling's Law. We attempted to influence the osmotic balance and reduce the inflammatory response in order to reduce the edema. METHODS: Thirty-six patients who underwent cardiac surgery were randomly allocated into four groups. Group A received albumin and mannitol into the pump prime. Group B had an, heparin-coated perfusion system, Group C had a leukocyte-depletion arterial line filter and Group D was the control group, where intraocular pressure was also measured. RESULTS: Lower leg muscle compartment pressure increased significantly during and after cardiac surgery in all groups, but this increase was significantly less in Group A than in the control group 24 h after surgery. No correlation was found between muscular compartment pressure and intraocular pressure. The intraocular pressure profile is different from the muscular compartment pressure and recovers much faster. CONCLUSION: Lower leg muscle compartment pressure and intraocular pressure behave differently during and after cardiac surgery. Albumin and mannitol added to the pump prime decreases muscle compartment pressure after cardiac surgery.en
dc.language.isoenen
dc.publisherSAGE Publicationsen
dc.relation.urlhttp://search.ebscohost.com/login.aspx?direct=true&db=aph&AN=20619048&site=ehost-liveen
dc.subject.meshCardiopulmonary Bypassen
dc.subject.meshDiuretics, Osmoticen
dc.subject.meshEdemaen
dc.subject.meshHemodilutionen
dc.subject.meshInflammationen
dc.subject.meshIntraocular Pressureen
dc.subject.meshLeukocyte Reduction Proceduresen
dc.subject.meshMannitolen
dc.subject.meshMuscle, Skeletalen
dc.subject.meshSerum Albuminen
dc.titleChanges in muscle compartment pressure after cardiopulmonary bypassen
dc.typeArticleen
dc.identifier.journalPerfusionen
dc.format.digYES-

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