Perioperative fluid management: comparison of high, medium and low fluid volume on tissue oxygen pressure in the small bowel and colon.

2.50
Hdl Handle:
http://hdl.handle.net/2336/14601
Title:
Perioperative fluid management: comparison of high, medium and low fluid volume on tissue oxygen pressure in the small bowel and colon.
Authors:
Hiltebrand, L B; Pestel, G; Hager, H; Ratnaraj, J; Sigurdsson, G H; Kurz, A
Citation:
Eur J Anaesthesiol 2007, 24(11):927-33
Issue Date:
1-Nov-2007
Abstract:
SummaryBackground and objectiveInsufficient blood flow and oxygenation in the intestinal tract is associated with increased incidence of postoperative complications after bowel surgery. High fluid volume administration may prevent occult regional hypoperfusion and intestinal tissue hypoxia. We tested the hypothesis that high intraoperative fluid volume administration increases intestinal wall tissue oxygen pressure during laparotomy. METHODS: In all, 27 pigs were anaesthetized, ventilated and randomly assigned to one of the three treatment groups (n = 9 in each) receiving low (3 mL kg-1 h-1), medium (7 mL kg-1 h-1) or high (20 mL kg-1 h-1) fluid volume treatment with lactated Ringer's solution. All animals received 30% and 100% inspired oxygen in random order. Cardiac index was measured with thermodilution and tissue oxygen pressure with a micro-oximetry system in the jejunum and colon wall and subcutaneous tissue. RESULTS: Groups receiving low and medium fluid volume treatment had similar systemic haemodynamics. The high fluid volume group had significantly higher mean arterial pressure, cardiac index and subcutaneous tissue oxygenation. Tissue oxygen pressures in the jejunum and colon were comparable in all three groups. CONCLUSIONS: The three different fluid volume regimens tested did not affect tissue oxygen pressure in the jejunum and colon, suggesting efficient autoregulation of intestinal blood flow in healthy subjects undergoing uncomplicated abdominal surgery.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Link field
Additional Links:
http://dx.doi.org/10.1017/S0265021507000816

Full metadata record

DC FieldValue Language
dc.contributor.authorHiltebrand, L B-
dc.contributor.authorPestel, G-
dc.contributor.authorHager, H-
dc.contributor.authorRatnaraj, J-
dc.contributor.authorSigurdsson, G H-
dc.contributor.authorKurz, A-
dc.date.accessioned2007-11-19T11:42:21Z-
dc.date.available2007-11-19T11:42:21Z-
dc.date.issued2007-11-01-
dc.date.submitted2007-11-19-
dc.identifier.citationEur J Anaesthesiol 2007, 24(11):927-33en
dc.identifier.issn0265-0215-
dc.identifier.pmid17582246-
dc.identifier.doi10.1017/S0265021507000816-
dc.identifier.otherAAA12-
dc.identifier.urihttp://hdl.handle.net/2336/14601-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Link fielden
dc.description.abstractSummaryBackground and objectiveInsufficient blood flow and oxygenation in the intestinal tract is associated with increased incidence of postoperative complications after bowel surgery. High fluid volume administration may prevent occult regional hypoperfusion and intestinal tissue hypoxia. We tested the hypothesis that high intraoperative fluid volume administration increases intestinal wall tissue oxygen pressure during laparotomy. METHODS: In all, 27 pigs were anaesthetized, ventilated and randomly assigned to one of the three treatment groups (n = 9 in each) receiving low (3 mL kg-1 h-1), medium (7 mL kg-1 h-1) or high (20 mL kg-1 h-1) fluid volume treatment with lactated Ringer's solution. All animals received 30% and 100% inspired oxygen in random order. Cardiac index was measured with thermodilution and tissue oxygen pressure with a micro-oximetry system in the jejunum and colon wall and subcutaneous tissue. RESULTS: Groups receiving low and medium fluid volume treatment had similar systemic haemodynamics. The high fluid volume group had significantly higher mean arterial pressure, cardiac index and subcutaneous tissue oxygenation. Tissue oxygen pressures in the jejunum and colon were comparable in all three groups. CONCLUSIONS: The three different fluid volume regimens tested did not affect tissue oxygen pressure in the jejunum and colon, suggesting efficient autoregulation of intestinal blood flow in healthy subjects undergoing uncomplicated abdominal surgery.en
dc.language.isoenen
dc.publisherCambridge University Pressen
dc.relation.urlhttp://dx.doi.org/10.1017/S0265021507000816en
dc.subject.meshPubMed - in processen
dc.titlePerioperative fluid management: comparison of high, medium and low fluid volume on tissue oxygen pressure in the small bowel and colon.en
dc.typeArticleen
dc.format.digYES-

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