Impact of fish intake on oxidative stress when included into a moderate energy-restricted program to treat obesity.

2.50
Hdl Handle:
http://hdl.handle.net/2336/15533
Title:
Impact of fish intake on oxidative stress when included into a moderate energy-restricted program to treat obesity.
Authors:
Parra, Dolores; Bandarra, Narcisa M; Kiely, Mairead; Thorsdottir, Inga; Martínez, J Alfredo
Citation:
Eur J Nutr. 2007, 46(8):460-7
Issue Date:
14-Dec-2007
Abstract:
BACKGROUND: The role of some nutritional factors and hypocaloric diets on oxidative balance is a matter of debate, especially related to the prevention and treatment of obesity and co-morbidities. AIM OF THE STUDY: The aim was to investigate the antioxidant capacity of different energy restricted diets in the treatment of obesity, paying emphasis to the effect of incorporating omega-3 fatty acids with or without other seafood components. METHODS: The study was a randomized 8-weeks parallel intervention trial prescribed to lose weight, which was implemented in 276 subjects aged 31.4 +/- 5.4 y.o. following four different balanced hypocaloric diets (TEE-30%): fish-restricted (control), cod and salmon based diets and DHA+EPA supplemented administration. At baseline (day 0) and at the end of the trial (day 56), anthropometry, dietary intake, erythrocyte membrane fatty acid content, circulating malondialdehyde (MDA) and plasma antioxidant status (AOP) were determined. RESULTS: Overall, percent weight loss was -5.8 +/- 3.2% (P < 0.001) and the AOP statistically increased after the energy restriction period (P = 0.015), basically due to the seafood-based diets. In contrast, MDA statistically only decreased (P = 0.026) after the cod-based diet intake with no changes after the other nutritional treatments. In fact, the cod-based intervention statistically decreased oxidative stress when expressed as the MDA/AOP ratio (P = 0.006). CONCLUSIONS: A moderate calorie-restricted cod-based diet was found as a useful strategy to lose weight, which was accompanied by a specific improvement on oxidative stress markers. The low saturated fat content and the seafood protein source of this diet may be important factors involved in these findings.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.springerlink.com/content/438688530t01m861

Full metadata record

DC FieldValue Language
dc.contributor.authorParra, Dolores-
dc.contributor.authorBandarra, Narcisa M-
dc.contributor.authorKiely, Mairead-
dc.contributor.authorThorsdottir, Inga-
dc.contributor.authorMartínez, J Alfredo-
dc.date.accessioned2007-12-28T14:52:59Z-
dc.date.available2007-12-28T14:52:59Z-
dc.date.issued2007-12-14-
dc.date.submitted2007-12-28-
dc.identifier.citationEur J Nutr. 2007, 46(8):460-7en
dc.identifier.issn1436-6207-
dc.identifier.pmid18026868-
dc.identifier.doi10.1007/s00394-007-0686-3-
dc.identifier.otherNUR12-
dc.identifier.urihttp://hdl.handle.net/2336/15533-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractBACKGROUND: The role of some nutritional factors and hypocaloric diets on oxidative balance is a matter of debate, especially related to the prevention and treatment of obesity and co-morbidities. AIM OF THE STUDY: The aim was to investigate the antioxidant capacity of different energy restricted diets in the treatment of obesity, paying emphasis to the effect of incorporating omega-3 fatty acids with or without other seafood components. METHODS: The study was a randomized 8-weeks parallel intervention trial prescribed to lose weight, which was implemented in 276 subjects aged 31.4 +/- 5.4 y.o. following four different balanced hypocaloric diets (TEE-30%): fish-restricted (control), cod and salmon based diets and DHA+EPA supplemented administration. At baseline (day 0) and at the end of the trial (day 56), anthropometry, dietary intake, erythrocyte membrane fatty acid content, circulating malondialdehyde (MDA) and plasma antioxidant status (AOP) were determined. RESULTS: Overall, percent weight loss was -5.8 +/- 3.2% (P < 0.001) and the AOP statistically increased after the energy restriction period (P = 0.015), basically due to the seafood-based diets. In contrast, MDA statistically only decreased (P = 0.026) after the cod-based diet intake with no changes after the other nutritional treatments. In fact, the cod-based intervention statistically decreased oxidative stress when expressed as the MDA/AOP ratio (P = 0.006). CONCLUSIONS: A moderate calorie-restricted cod-based diet was found as a useful strategy to lose weight, which was accompanied by a specific improvement on oxidative stress markers. The low saturated fat content and the seafood protein source of this diet may be important factors involved in these findings.en
dc.language.isoenen
dc.publisherSteinkopffen
dc.relation.urlhttp://www.springerlink.com/content/438688530t01m861en
dc.subject.meshPubMed - in processen
dc.titleImpact of fish intake on oxidative stress when included into a moderate energy-restricted program to treat obesity.en
dc.typeArticleen
dc.identifier.eissn1436-6215-
dc.contributor.departmentInstitute of Nutrition and Food Sciences, University of Navarra, C/Irunlarrea s/n, Pamplona, 31008, Spain, jalfmtz@unav.es.en
dc.identifier.journalEuropean journal of nutritionen
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