Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables.

2.50
Hdl Handle:
http://hdl.handle.net/2336/15738
Title:
Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables.
Authors:
Arnarsson, Arsaell; Damji, Karim F; Sverrisson, Thordur; Sasaki, Hiroshi; Jonasson, Fridbert
Citation:
Acta Ophthalmol Scand. 2007, 85(8):822-7
Issue Date:
1-Dec-2007
Abstract:
PURPOSE: To examine the age and sex-specific prevalence of pseudoexfoliation syndrome (PEX) and its relationship with some ophthalmological variables. METHODS: We carried out a population-based study using a random sample taken from the national population census for citizens of Reykjavik, aged > or = 50 years. A total of 1045 individuals participated in all parts of the study. Pseudoexfoliation was established by slit-lamp examination with a maximally dilated pupil carried out by two experienced ophthalmologists, who were masked to one another's results except in cases of disagreement where they had to reach a consensus. RESULTS: In all, 108 (10.7%) persons were found to have PEX in at least one eye. Prevalence increased from 2.5% in those aged 50-59 years to 40.6% in those aged > or = 80 years. Women were more frequently affected than men (12.3% versus 8.7%). This difference remained statistically significant after controlling for the effect of age (p < 0.001). Eyes with PEX were found to have higher intraocular pressure (IOP) than eyes without PEX (p < 0.05). However, PEX was not found to be related to central corneal thickness, anterior chamber depth, lens thickness, nuclear lens opacifications or optic disc morphology in a multivariate model. CONCLUSIONS: Pseudoexfoliation is an age-related phenomenon commonly found in Iceland. It is more commonly found in women than in men and is associated with elevated IOP.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1600-0420.2007.01051.x

Full metadata record

DC FieldValue Language
dc.contributor.authorArnarsson, Arsaell-
dc.contributor.authorDamji, Karim F-
dc.contributor.authorSverrisson, Thordur-
dc.contributor.authorSasaki, Hiroshi-
dc.contributor.authorJonasson, Fridbert-
dc.date.accessioned2008-01-07T12:24:31Z-
dc.date.available2008-01-07T12:24:31Z-
dc.date.issued2007-12-01-
dc.date.submitted2007-01-07-
dc.identifier.citationActa Ophthalmol Scand. 2007, 85(8):822-7en
dc.identifier.issn1600-0420-
dc.identifier.pmid18028119-
dc.identifier.doi10.1111/j.1600-0420.2007.01051.x-
dc.identifier.urihttp://hdl.handle.net/2336/15738-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractPURPOSE: To examine the age and sex-specific prevalence of pseudoexfoliation syndrome (PEX) and its relationship with some ophthalmological variables. METHODS: We carried out a population-based study using a random sample taken from the national population census for citizens of Reykjavik, aged > or = 50 years. A total of 1045 individuals participated in all parts of the study. Pseudoexfoliation was established by slit-lamp examination with a maximally dilated pupil carried out by two experienced ophthalmologists, who were masked to one another's results except in cases of disagreement where they had to reach a consensus. RESULTS: In all, 108 (10.7%) persons were found to have PEX in at least one eye. Prevalence increased from 2.5% in those aged 50-59 years to 40.6% in those aged > or = 80 years. Women were more frequently affected than men (12.3% versus 8.7%). This difference remained statistically significant after controlling for the effect of age (p < 0.001). Eyes with PEX were found to have higher intraocular pressure (IOP) than eyes without PEX (p < 0.05). However, PEX was not found to be related to central corneal thickness, anterior chamber depth, lens thickness, nuclear lens opacifications or optic disc morphology in a multivariate model. CONCLUSIONS: Pseudoexfoliation is an age-related phenomenon commonly found in Iceland. It is more commonly found in women than in men and is associated with elevated IOP.en
dc.language.isoenen
dc.publisherMunksgaarden
dc.relation.urlhttp://www.blackwell-synergy.com/doi/abs/10.1111/j.1600-0420.2007.01051.xen
dc.subject.meshAge Distributionen
dc.subject.meshAgeden
dc.subject.meshAged, 80 and overen
dc.subject.meshExfoliation Syndromeen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshIcelanden
dc.subject.meshIntraocular Pressureen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshPrevalenceen
dc.subject.meshSex Distributionen
dc.titlePseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables.en
dc.typeArticleen
dc.contributor.departmentDepartment of Ophthalmology, University of Iceland, Reykjavik, Iceland.en
dc.identifier.journalActa ophthalmologica Scandinavicaen

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