Factors affecting adherence to asthma treatment in an international cohort of young and middle-aged adults

2.50
Hdl Handle:
http://hdl.handle.net/2336/15745
Title:
Factors affecting adherence to asthma treatment in an international cohort of young and middle-aged adults
Authors:
Corsico, Angelo G; Cazzoletti, Lucia; de Marco, Roberto; Janson, Christer; Jarvis, Deborah; Zoia, Maria C; Bugiani, Massimiliano; Accordini, Simone; Villani, Simona; Marinoni, Alessandra; Gislason, David; Gulsvik, Amund; Pin, Isabelle; Vermeire, Paul; Cerveri, Isa
Citation:
Respir Med. 2007, 101(6):1363-7
Issue Date:
1-Jun-2007
Abstract:
BACKGROUND: A major reason of the poor control of asthma is that patients fail to adhere to their treatment. The aim of the study was to identify factors affecting changes in asthma treatment adherence in an international cohort. METHODS: A follow-up study was carried out by means of a structured clinical interview in 971 subjects with asthma from 12 countries who participated in both the European Community Respiratory Health Survey: ECRHS-I (1990-94) and ECRHS-II (1998-2002). Subjects were considered adherent if they reported they normally took all the prescribed drugs. A logistic model was used to study the adjusted effect of the determinants. RESULTS: The net change in adherence to anti-asthmatic treatment per 10 years of follow-up was -2% (95% CI: -9.5, 5.5), 7.5% (-2.6, 17.6), 15.0% (6.6, 23.5) and 19.8% (4.1, 35.5), respectively, in Nordic, Mediterranean, Continental and extra-European areas. Among the 428 non-adherent subjects in ECRHS-I, having regular consultations with health care professionals was the strongest predictor of increased adherence (OR 3.32; 95% CI: 1.08-10.17). Among the 543 adherent subjects in ECRHS-I, using inhaled corticosteroids significantly predicted a persistence of adherence (OR 2.04; 95% CI: 1.11-3.75). No effect of gender, age, duration of the disease, smoking habit and educational level was observed. CONCLUSIONS: Our findings highlight the key role of doctors and nurses in educating and regularly reviewing the patients and support the efforts for an improvement of clinical communication.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.sciencedirect.com/science/article/B6WWS-4MNHY0M-2/2/ab6434628815bb736ad1196e65d2c0f5

Full metadata record

DC FieldValue Language
dc.contributor.authorCorsico, Angelo G-
dc.contributor.authorCazzoletti, Lucia-
dc.contributor.authorde Marco, Roberto-
dc.contributor.authorJanson, Christer-
dc.contributor.authorJarvis, Deborah-
dc.contributor.authorZoia, Maria C-
dc.contributor.authorBugiani, Massimiliano-
dc.contributor.authorAccordini, Simone-
dc.contributor.authorVillani, Simona-
dc.contributor.authorMarinoni, Alessandra-
dc.contributor.authorGislason, David-
dc.contributor.authorGulsvik, Amund-
dc.contributor.authorPin, Isabelle-
dc.contributor.authorVermeire, Paul-
dc.contributor.authorCerveri, Isa-
dc.date.accessioned2008-01-07T15:25:05Z-
dc.date.available2008-01-07T15:25:05Z-
dc.date.issued2007-06-01-
dc.date.submitted2007-01-07-
dc.identifier.citationRespir Med. 2007, 101(6):1363-7en
dc.identifier.issn0954-6111-
dc.identifier.pmid17188854-
dc.identifier.doi10.1016/j.rmed.2006.11.012-
dc.identifier.urihttp://hdl.handle.net/2336/15745-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractBACKGROUND: A major reason of the poor control of asthma is that patients fail to adhere to their treatment. The aim of the study was to identify factors affecting changes in asthma treatment adherence in an international cohort. METHODS: A follow-up study was carried out by means of a structured clinical interview in 971 subjects with asthma from 12 countries who participated in both the European Community Respiratory Health Survey: ECRHS-I (1990-94) and ECRHS-II (1998-2002). Subjects were considered adherent if they reported they normally took all the prescribed drugs. A logistic model was used to study the adjusted effect of the determinants. RESULTS: The net change in adherence to anti-asthmatic treatment per 10 years of follow-up was -2% (95% CI: -9.5, 5.5), 7.5% (-2.6, 17.6), 15.0% (6.6, 23.5) and 19.8% (4.1, 35.5), respectively, in Nordic, Mediterranean, Continental and extra-European areas. Among the 428 non-adherent subjects in ECRHS-I, having regular consultations with health care professionals was the strongest predictor of increased adherence (OR 3.32; 95% CI: 1.08-10.17). Among the 543 adherent subjects in ECRHS-I, using inhaled corticosteroids significantly predicted a persistence of adherence (OR 2.04; 95% CI: 1.11-3.75). No effect of gender, age, duration of the disease, smoking habit and educational level was observed. CONCLUSIONS: Our findings highlight the key role of doctors and nurses in educating and regularly reviewing the patients and support the efforts for an improvement of clinical communication.en
dc.language.isoenen
dc.publisherW.B. Saundersen
dc.relation.urlhttp://www.sciencedirect.com/science/article/B6WWS-4MNHY0M-2/2/ab6434628815bb736ad1196e65d2c0f5en
dc.subject.meshAdulten
dc.subject.meshAnti-Asthmatic Agentsen
dc.subject.meshAsthmaen
dc.subject.meshEpidemiologic Methodsen
dc.subject.meshFemaleen
dc.subject.meshGlucocorticoidsen
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshPatient Acceptance of Health Careen
dc.subject.meshPatient Complianceen
dc.subject.meshPatient Selectionen
dc.titleFactors affecting adherence to asthma treatment in an international cohort of young and middle-aged adultsen
dc.typeArticleen
dc.contributor.departmentDepartment of Allergy, Respiratory Medicine and Sleep, University Hospital, Reykjavik, Icelanden
dc.identifier.journalRespiratory medicineen

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