Arfbundin kólesterólhækkun : yfirlit yfir stöðu þekkingar og árangur markvissrar leitar á Íslandi

2.50
Hdl Handle:
http://hdl.handle.net/2336/20893
Title:
Arfbundin kólesterólhækkun : yfirlit yfir stöðu þekkingar og árangur markvissrar leitar á Íslandi
Other Titles:
Familial hypercholesterolemia in Iceland. Review and outcome of family screening
Authors:
Bolli Þórsson; Vilmundur Guðnason; Guðrún Þorvaldsdóttir; Gunnar Sigurðsson
Citation:
Læknablaðið 2001, 87(6):513-8
Issue Date:
1-Jun-2001
Abstract:
Familial hypercholesterolemia is a genetic disorder causing lifelong elevation of cholesterol and severely increased risk of coronary heart disease. Cholesterol lowering drug treatment is usually effective and clinical trials indicate a substantial lowering of risk, thanks to treatment. The diagnosis is based on cholesterol level in the individual and in his/her closest relatives or on a genetic test. The prevalence is estimated 1/500. In Iceland nearly half of the estimated number of individuals with familial hypercholesterolemia has been diagnosed (about 200). Three mutations have been identified that cause familial hypercholesterolemia in the Icelandic population and the most common one is estimated to cause 60% of the disease in Iceland. In this paper we give a short review of the literature on familial hypercholesterolemia especially regarding risk of coronary heart disease and describe the results of screening for the disease in Iceland. Also we present a new campaign to find undiagnosed individuals with the disease.
Description:
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open
Additional Links:
http://www.laeknabladid.is

Full metadata record

DC FieldValue Language
dc.contributor.authorBolli Þórsson-
dc.contributor.authorVilmundur Guðnason-
dc.contributor.authorGuðrún Þorvaldsdóttir-
dc.contributor.authorGunnar Sigurðsson-
dc.date.accessioned2008-03-17T11:56:19Z-
dc.date.available2008-03-17T11:56:19Z-
dc.date.issued2001-06-01-
dc.date.submitted2008-03-17-
dc.identifier.citationLæknablaðið 2001, 87(6):513-8en
dc.identifier.issn0023-7213-
dc.identifier.pmid17018991-
dc.identifier.urihttp://hdl.handle.net/2336/20893-
dc.descriptionNeðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Openen
dc.description.abstractFamilial hypercholesterolemia is a genetic disorder causing lifelong elevation of cholesterol and severely increased risk of coronary heart disease. Cholesterol lowering drug treatment is usually effective and clinical trials indicate a substantial lowering of risk, thanks to treatment. The diagnosis is based on cholesterol level in the individual and in his/her closest relatives or on a genetic test. The prevalence is estimated 1/500. In Iceland nearly half of the estimated number of individuals with familial hypercholesterolemia has been diagnosed (about 200). Three mutations have been identified that cause familial hypercholesterolemia in the Icelandic population and the most common one is estimated to cause 60% of the disease in Iceland. In this paper we give a short review of the literature on familial hypercholesterolemia especially regarding risk of coronary heart disease and describe the results of screening for the disease in Iceland. Also we present a new campaign to find undiagnosed individuals with the disease.en
dc.languageICE-
dc.language.isoisen
dc.publisherLæknafélag Íslands, Læknafélag Reykjavíkuren
dc.relation.urlhttp://www.laeknabladid.isen
dc.subjectKransæðasjúkdómaren
dc.subjectSkimunen
dc.subjectÆttgengien
dc.subjectBlóðfitaen
dc.subject.classificationLBL12-
dc.subject.meshHypercholesterolemiaen
dc.subject.meshMass Screeningen
dc.subject.meshCoronary Diseaseen
dc.titleArfbundin kólesterólhækkun : yfirlit yfir stöðu þekkingar og árangur markvissrar leitar á Íslandiis
dc.title.alternativeFamilial hypercholesterolemia in Iceland. Review and outcome of family screeningen
dc.typeArticleen
dc.contributor.departmentIcelandic Heart Association, Hlíðasmára 1, 201 Kópavogi, Iceland. bolli@hjarta.is.en
dc.identifier.journalLæknablaðiðen
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