Autism spectrum disorders in children with a history of infantile spasms: a population-based study.

2.50
Hdl Handle:
http://hdl.handle.net/2336/21449
Title:
Autism spectrum disorders in children with a history of infantile spasms: a population-based study.
Authors:
Saemundsen, Evald; Ludvigsson, Petur; Rafnsson, Vilhjalmur
Citation:
J. Child Neurol. 2007, 22(9):1102-7
Issue Date:
1-Sep-2007
Abstract:
The objective of this article is to describe autistic spectrum disorders in children diagnosed with infantile spasms in the first year of life. The source of data was the records of all 3 pediatric departments in Iceland. Twenty children born between 1981 and 1998 who had infantile spasms were invited to participate. When appropriate, the parents of these children were asked to complete the Social Communication Questionnaire. Children scoring 10 points or higher on the questionnaire were selected for further examination using the Autism Diagnostic Interview- Revised and either the Autism Diagnostic Observation Schedule or the Childhood Autism Rating Scale. All participants were given appropriate cognitive tests or measures of adaptive behavior. The parents of 17 children (10 boys, 7 girls) agreed to participate in the study. Age at assessment ranged from 5 to 19 years with a mean age of 11 years and 6 months. Fourteen children had at least one neurodevelopmental disorder. Six (6/17), or 35.3%, were diagnosed with autism spectrum disorder (3 boys, 3 girls), five of these had a history of symptomatic infantile spasms, and four were profoundly mentally retarded (IQ/DQ<20). If the diagnosis of autism spectrum disorder was restricted to children with a developmental age of 24 months or more (3 cases), the prevalence was 17.6%. The estimates found in this study exceed the estimated prevalence of autism spectrum disorder in the general population.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://jcn.sagepub.com/cgi/content/abstract/22/9/1102

Full metadata record

DC FieldValue Language
dc.contributor.authorSaemundsen, Evald-
dc.contributor.authorLudvigsson, Petur-
dc.contributor.authorRafnsson, Vilhjalmur-
dc.date.accessioned2008-03-25T15:03:32Z-
dc.date.available2008-03-25T15:03:32Z-
dc.date.issued2007-09-01-
dc.date.submitted2008-03-25-
dc.identifier.citationJ. Child Neurol. 2007, 22(9):1102-7en
dc.identifier.issn0883-0738-
dc.identifier.pmid17890408-
dc.identifier.doi10.1177/0883073807306251-
dc.identifier.urihttp://hdl.handle.net/2336/21449-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractThe objective of this article is to describe autistic spectrum disorders in children diagnosed with infantile spasms in the first year of life. The source of data was the records of all 3 pediatric departments in Iceland. Twenty children born between 1981 and 1998 who had infantile spasms were invited to participate. When appropriate, the parents of these children were asked to complete the Social Communication Questionnaire. Children scoring 10 points or higher on the questionnaire were selected for further examination using the Autism Diagnostic Interview- Revised and either the Autism Diagnostic Observation Schedule or the Childhood Autism Rating Scale. All participants were given appropriate cognitive tests or measures of adaptive behavior. The parents of 17 children (10 boys, 7 girls) agreed to participate in the study. Age at assessment ranged from 5 to 19 years with a mean age of 11 years and 6 months. Fourteen children had at least one neurodevelopmental disorder. Six (6/17), or 35.3%, were diagnosed with autism spectrum disorder (3 boys, 3 girls), five of these had a history of symptomatic infantile spasms, and four were profoundly mentally retarded (IQ/DQ<20). If the diagnosis of autism spectrum disorder was restricted to children with a developmental age of 24 months or more (3 cases), the prevalence was 17.6%. The estimates found in this study exceed the estimated prevalence of autism spectrum disorder in the general population.en
dc.language.isoenen
dc.publisherBC Deckeren
dc.relation.urlhttp://jcn.sagepub.com/cgi/content/abstract/22/9/1102en
dc.subject.meshAdolescenten
dc.subject.meshAsphyxia Neonatorumen
dc.subject.meshAutistic Disorderen
dc.subject.meshBrainen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshCohort Studiesen
dc.subject.meshComorbidityen
dc.subject.meshEpilepsyen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshHypoxia-Ischemia, Brainen
dc.subject.meshIcelanden
dc.subject.meshInfant, Newbornen
dc.subject.meshMagnetic Resonance Imagingen
dc.subject.meshMaleen
dc.subject.meshMental Retardationen
dc.subject.meshNervous System Malformationsen
dc.subject.meshNeuropsychological Testsen
dc.subject.meshPrevalenceen
dc.subject.meshQuestionnairesen
dc.subject.meshSpasms, Infantileen
dc.titleAutism spectrum disorders in children with a history of infantile spasms: a population-based study.en
dc.typeArticleen
dc.contributor.departmentDivision of Autism and Communication Disorders, State Diagnostic and Counseling Center, Kopavogur, Iceland. evald@greining.isen
dc.identifier.journalJournal of child neurologyen

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