2.50
Hdl Handle:
http://hdl.handle.net/2336/2776
Title:
The association between birth size and atopy in young North-European adults
Authors:
Laerum, B N; Svanes, C; Wentzel-Larsen, T; Gulsvik, A; Iversen, M; Gislason, T; Jögi, R; Norrman, E; Janson, C; Omenaas, E
Citation:
Clin. Exp. Allergy 2005, 35(8):1022-7
Issue Date:
1-Aug-2005
Abstract:
BACKGROUND: There is evidence that atopic disorders may begin in intra-uterine life; however, studies of birth characteristics and atopy show conflicting results. METHODS: We wanted to investigate the association of birth weight and head circumference with serum total or specific IgE, allergic rhinitis or eczema while addressing the influence of demographic and geographical factors. In this historic prospective cohort study, data were collected from birth records for 1683 men and women born in 1947-1973, from six Nordic-Baltic populations participating in the European Community Respiratory Health Survey. Blood tests for the measurement of serum total and specific IgE were available for 1494 subjects. In multiple regression analyses, adjustments were made for birth length, gender, age, study centre, adult body mass index, level of education, parental and adult smoking. RESULTS There was no association of birth weight (n=1230) and head circumference (n=285) with serum total IgE, specific IgE antibodies, allergic rhinitis or eczema. There were neither significant interactions by gender or age, nor heterogeneity between the study centres in the analyses of birth weight and adult atopy. CONCLUSION: Birth size was not associated with atopy among adults in this large Nordic-Baltic population study.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.blackwell-synergy.com/doi/full/10.1111/j.1365-2222.2005.02289.x

Full metadata record

DC FieldValue Language
dc.contributor.authorLaerum, B N-
dc.contributor.authorSvanes, C-
dc.contributor.authorWentzel-Larsen, T-
dc.contributor.authorGulsvik, A-
dc.contributor.authorIversen, M-
dc.contributor.authorGislason, T-
dc.contributor.authorJögi, R-
dc.contributor.authorNorrman, E-
dc.contributor.authorJanson, C-
dc.contributor.authorOmenaas, E-
dc.date.accessioned2006-05-17T14:02:16Z-
dc.date.available2006-05-17T14:02:16Z-
dc.date.issued2005-08-01-
dc.identifier.citationClin. Exp. Allergy 2005, 35(8):1022-7en
dc.identifier.issn0954-7894-
dc.identifier.pmid16120083-
dc.identifier.doi10.1111/j.1365-2222.2005.02289.x-
dc.identifier.urihttp://hdl.handle.net/2336/2776-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractBACKGROUND: There is evidence that atopic disorders may begin in intra-uterine life; however, studies of birth characteristics and atopy show conflicting results. METHODS: We wanted to investigate the association of birth weight and head circumference with serum total or specific IgE, allergic rhinitis or eczema while addressing the influence of demographic and geographical factors. In this historic prospective cohort study, data were collected from birth records for 1683 men and women born in 1947-1973, from six Nordic-Baltic populations participating in the European Community Respiratory Health Survey. Blood tests for the measurement of serum total and specific IgE were available for 1494 subjects. In multiple regression analyses, adjustments were made for birth length, gender, age, study centre, adult body mass index, level of education, parental and adult smoking. RESULTS There was no association of birth weight (n=1230) and head circumference (n=285) with serum total IgE, specific IgE antibodies, allergic rhinitis or eczema. There were neither significant interactions by gender or age, nor heterogeneity between the study centres in the analyses of birth weight and adult atopy. CONCLUSION: Birth size was not associated with atopy among adults in this large Nordic-Baltic population study.en
dc.language.isoenen
dc.publisherBlackwell Scientific Publicationsen
dc.relation.urlhttp://www.blackwell-synergy.com/doi/full/10.1111/j.1365-2222.2005.02289.xen
dc.subjectAdulten
dc.subjectAge Distributionen
dc.subjectBirth Weighten
dc.subjectDenmark/epidemiologyen
dc.subjectEczemaen
dc.subjectEstoniaen
dc.subjectFemaleen
dc.subjectHeaden
dc.subjectHumansen
dc.subjectIceland/epidemiologyen
dc.subjectImmunoglobulin Een
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectNorway/epidemiologyen
dc.subjectPopulation Surveillanceen
dc.subjectPrevalenceen
dc.subjectProspective Studiesen
dc.subjectRespiratory Hypersensitivityen
dc.subjectSex Distributionen
dc.subjectSweden/epidemiologyen
dc.titleThe association between birth size and atopy in young North-European adultsen
dc.typeArticleen
dc.identifier.journalClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunologyen
dc.format.digYES-

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