Effective treatment of experimental acute otitis media by application of volatile fluids into the ear canal

2.50
Hdl Handle:
http://hdl.handle.net/2336/2865
Title:
Effective treatment of experimental acute otitis media by application of volatile fluids into the ear canal
Authors:
Kristinsson, Karl G; Magnusdottir, Anna B; Petersen, Hannes; Hermansson, Ann
Citation:
J. Infect. Dis. 2005, 191(11):1876-80
Issue Date:
1-Jun-2005
Abstract:
Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil (Ocimum basilicum) and essential oil components (thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination and middle ear cultures. The treatment with oil of basil or essential oil components cured or healed 56%-81% of rats infected with H. influenzae and 6%-75% of rats infected with pneumococci, compared with 5.6%-6% of rats in the placebo group. Essential oils or their components placed in the ear canal can provide effective treatment of acute otitis media.
Description:
To access publisher version of this article. Please click on the hyperlink in Additional Link field; To access full text version of this article. Please click on the hyperlink "View/Open" at the bottom of this page
Additional Links:
http://www.journals.uchicago.edu/doi/abs/10.1086/430003

Full metadata record

DC FieldValue Language
dc.contributor.authorKristinsson, Karl G-
dc.contributor.authorMagnusdottir, Anna B-
dc.contributor.authorPetersen, Hannes-
dc.contributor.authorHermansson, Ann-
dc.date.accessioned2006-05-19T10:39:57Z-
dc.date.available2006-05-19T10:39:57Z-
dc.date.issued2005-06-01-
dc.identifier.citationJ. Infect. Dis. 2005, 191(11):1876-80en
dc.identifier.issn0022-1899-
dc.identifier.pmid15871121-
dc.identifier.doi10.1086/430003-
dc.identifier.urihttp://hdl.handle.net/2336/2865-
dc.descriptionTo access publisher version of this article. Please click on the hyperlink in Additional Link fielden
dc.descriptionTo access full text version of this article. Please click on the hyperlink "View/Open" at the bottom of this pageen
dc.description.abstractEssential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil (Ocimum basilicum) and essential oil components (thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination and middle ear cultures. The treatment with oil of basil or essential oil components cured or healed 56%-81% of rats infected with H. influenzae and 6%-75% of rats infected with pneumococci, compared with 5.6%-6% of rats in the placebo group. Essential oils or their components placed in the ear canal can provide effective treatment of acute otitis media.en
dc.language.isoenen
dc.publisherUniversity of Chicago Pressen
dc.relation.urlhttp://www.journals.uchicago.edu/doi/abs/10.1086/430003en
dc.subjectAcute Diseaseen
dc.subjectAnimalsen
dc.subjectAnti-Bacterial Agentsen
dc.subjectComparative Studyen
dc.subjectHaemophilus Infectionsen
dc.subjectOcimum basilicumen
dc.subjectOils, Volatileen
dc.subjectOtitis Mediaen
dc.subjectPlant Extractsen
dc.subjectPneumococcal Infectionsen
dc.subjectRats, Sprague-Dawleyen
dc.titleEffective treatment of experimental acute otitis media by application of volatile fluids into the ear canalen
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Microbiology, Landspitali University Hospital, Reykjavik, Iceland. karl@landspitali.isis
dc.identifier.journalJournal of infectious diseasesen
dc.format.digYES-
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