2.50
Hdl Handle:
http://hdl.handle.net/2336/29345
Title:
Lág þéttni natríums í sermi fyrirbura
Other Titles:
Hyponatremia in very low birth weight infants
Authors:
Kristján Guðmundsson; Þórður Þórkelsson; Gestur Pálsson; Hörður Bergsteinsson; Sveinn Kjartansson; Ásgeir Haraldsson; Atli Dagbjartsson
Citation:
Læknablaðið 2008, 94(4):287-91
Issue Date:
2-Apr-2008
Abstract:
AIM: Hyponatremia can potentially have serious effects in the premature infant, Therefore, it is important to recognize its causes and prevent it if possible. The aim of this study was to evaluate the causes of hyponatremia in very low birth weight (VLBW) infants cared for at the Neonatal Intensive Care Unit (NICU) of Children's Hospital Iceland. SUBJECTS AND METHODS: Retrospective descriptive study of 20 VLBW infants at the NICU of Children's Hospital Iceland, born after <30 weeks gestation with birth weight of < or =1250 g. Information was obtained on fluid administration, weight loss, sodium administration and serum sodium concentrations during their first ten days of life. RESULTS: The median gestational age was 27 weeks (24-29 weeks) and the median birth weight was 905 g (620-1250 g). A negative correlation was found between birth weight and the amount of fluids given (R2=-0.42; p=0.002). The median weight loss was 10.6% (3.1-29.5%). A positive correlation was found between weight loss and the amount of fluids the infants received (R2=0.76; p<0.001). The amount of sodium given was on the average 5.7+3.1 mmól/kg/24 hours. The median serum sodium concentration was 137 mmól/L (127-150 mmól/L). A negative correlation was found between the amount of sodium given and serum sodium concentrations (R2=-0.42; p<0.001). There was no correlation between the amount of fluids given and serum sodium concentrations (R2=0.006; p=0.7). A negative correlation was found between birth weight and serum sodium concentrations (R2=-0.24; p=0.027). CONCLUSION: High sodium requirements in VLBW infants at our hospital suggests that their hyponatremia is mainly due to the immaturity of their kidneys, which is known to result in excessive loss of sodium in the urine.; Markmið: Lág þéttni natríums í sermi fyrirbura getur haft alvarlegar afleiðingar í för með sér. Því er mikilvægt að þekkja orsakir þessa vandamáls og fyrirbyggja það ef unnt er. Markmið rannsóknarinnar var að kanna orsakir lágrar þéttni natríums í sermi minnstu fyrirburanna á vökudeild Barnaspítala Hringsins. Tilfelli og aðferðir: Afturskyggn lýsandi rannsókn á 20 fyrirburum á vökudeild Barnaspítala Hringsins sem fæddust eftir <30 vikna meðgöngu og með fæðingarþyngd <1250g. Upplýsingum var safnað um vökvagjöf, þyngd, natríumgjöf og þéttni natríums í blóði þeirra fyrstu 10 dagana eftir fæðingu. Niðurstöður: Miðgildi meðgöngulengdar barnanna var 27 vikur (24-29 vikur) og miðgildi fæðingarþyngdar þeirra var 905g (620-1250g). Neikvæð fylgni var milli fæðingarþyngdar og vökvamagns sem gefið var (R2=-0,42; p=0,002). Miðgildi þyngdartaps var 10,6% (3,1-29,5%). Jákvæð fylgni var milli þyngdartaps og vökvagjafar barnanna (R2=0,76; p<0,001). Natríumgjöf var að meðaltali 5,7+3,1 mmól/kg/sólarhring. Miðgildi þéttni natríums í sermi allra barnanna var 137 mmól/L (127-150 mmól/L). Neikvæð fylgni var milli natríumgjafar og þéttni natríums í sermi (R2=-0,42; p<0,001). Ekki var marktæk fylgni milli vökvagjafar og þéttni natríums í sermi (R2=0,006; p=0,7). Neikvæð fylgni var milli fæðingarþyngdar og natríumgjafar (R2=-0,24; p=0,027). Ályktun: Mikil natríumþörf minnstu fyrirburanna bendir til þess að lág þéttni natríums í sermi þeirra sé einkum vegna vanþroska nýrna þeirra, sem þekkt er að valda auknu tapi á natríum með þvagi.
Description:
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open
Additional Links:
http://www.laeknabladid.is

Full metadata record

DC FieldValue Language
dc.contributor.authorKristján Guðmundsson-
dc.contributor.authorÞórður Þórkelsson-
dc.contributor.authorGestur Pálsson-
dc.contributor.authorHörður Bergsteinsson-
dc.contributor.authorSveinn Kjartansson-
dc.contributor.authorÁsgeir Haraldsson-
dc.contributor.authorAtli Dagbjartsson-
dc.date.accessioned2008-06-02T15:30:26Z-
dc.date.available2008-06-02T15:30:26Z-
dc.date.issued2008-04-02-
dc.date.submitted2008-04-01-
dc.identifier.citationLæknablaðið 2008, 94(4):287-91en
dc.identifier.issn0023-7213-
dc.identifier.pmid18460727-
dc.identifier.urihttp://hdl.handle.net/2336/29345-
dc.descriptionNeðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Openen
dc.description.abstractAIM: Hyponatremia can potentially have serious effects in the premature infant, Therefore, it is important to recognize its causes and prevent it if possible. The aim of this study was to evaluate the causes of hyponatremia in very low birth weight (VLBW) infants cared for at the Neonatal Intensive Care Unit (NICU) of Children's Hospital Iceland. SUBJECTS AND METHODS: Retrospective descriptive study of 20 VLBW infants at the NICU of Children's Hospital Iceland, born after <30 weeks gestation with birth weight of < or =1250 g. Information was obtained on fluid administration, weight loss, sodium administration and serum sodium concentrations during their first ten days of life. RESULTS: The median gestational age was 27 weeks (24-29 weeks) and the median birth weight was 905 g (620-1250 g). A negative correlation was found between birth weight and the amount of fluids given (R2=-0.42; p=0.002). The median weight loss was 10.6% (3.1-29.5%). A positive correlation was found between weight loss and the amount of fluids the infants received (R2=0.76; p<0.001). The amount of sodium given was on the average 5.7+3.1 mmól/kg/24 hours. The median serum sodium concentration was 137 mmól/L (127-150 mmól/L). A negative correlation was found between the amount of sodium given and serum sodium concentrations (R2=-0.42; p<0.001). There was no correlation between the amount of fluids given and serum sodium concentrations (R2=0.006; p=0.7). A negative correlation was found between birth weight and serum sodium concentrations (R2=-0.24; p=0.027). CONCLUSION: High sodium requirements in VLBW infants at our hospital suggests that their hyponatremia is mainly due to the immaturity of their kidneys, which is known to result in excessive loss of sodium in the urine.en
dc.description.abstractMarkmið: Lág þéttni natríums í sermi fyrirbura getur haft alvarlegar afleiðingar í för með sér. Því er mikilvægt að þekkja orsakir þessa vandamáls og fyrirbyggja það ef unnt er. Markmið rannsóknarinnar var að kanna orsakir lágrar þéttni natríums í sermi minnstu fyrirburanna á vökudeild Barnaspítala Hringsins. Tilfelli og aðferðir: Afturskyggn lýsandi rannsókn á 20 fyrirburum á vökudeild Barnaspítala Hringsins sem fæddust eftir <30 vikna meðgöngu og með fæðingarþyngd <1250g. Upplýsingum var safnað um vökvagjöf, þyngd, natríumgjöf og þéttni natríums í blóði þeirra fyrstu 10 dagana eftir fæðingu. Niðurstöður: Miðgildi meðgöngulengdar barnanna var 27 vikur (24-29 vikur) og miðgildi fæðingarþyngdar þeirra var 905g (620-1250g). Neikvæð fylgni var milli fæðingarþyngdar og vökvamagns sem gefið var (R2=-0,42; p=0,002). Miðgildi þyngdartaps var 10,6% (3,1-29,5%). Jákvæð fylgni var milli þyngdartaps og vökvagjafar barnanna (R2=0,76; p<0,001). Natríumgjöf var að meðaltali 5,7+3,1 mmól/kg/sólarhring. Miðgildi þéttni natríums í sermi allra barnanna var 137 mmól/L (127-150 mmól/L). Neikvæð fylgni var milli natríumgjafar og þéttni natríums í sermi (R2=-0,42; p<0,001). Ekki var marktæk fylgni milli vökvagjafar og þéttni natríums í sermi (R2=0,006; p=0,7). Neikvæð fylgni var milli fæðingarþyngdar og natríumgjafar (R2=-0,24; p=0,027). Ályktun: Mikil natríumþörf minnstu fyrirburanna bendir til þess að lág þéttni natríums í sermi þeirra sé einkum vegna vanþroska nýrna þeirra, sem þekkt er að valda auknu tapi á natríum með þvagi.is
dc.languageice-
dc.language.isoisen
dc.publisherLæknafélag Íslands, Læknafélag Reykjavíkuren
dc.relation.urlhttp://www.laeknabladid.isen
dc.subjectFyrirburaren
dc.subjectFæðingarþyngden
dc.subject.meshBirth Weighten
dc.subject.meshFluid Therapyen
dc.subject.meshGestational Ageen
dc.subject.meshHumansen
dc.subject.meshHyponatremiaen
dc.subject.meshIcelanden
dc.subject.meshInfant, Newbornen
dc.subject.meshInfant, Very Low Birth Weighten
dc.subject.meshIntensive Care Units, Neonatalen
dc.subject.meshKidneyen
dc.subject.meshRetrospective Studiesen
dc.subject.meshRisk Factorsen
dc.subject.meshSodiumen
dc.subject.meshTime Factorsen
dc.subject.meshWeight Lossen
dc.titleLág þéttni natríums í sermi fyrirburais
dc.title.alternativeHyponatremia in very low birth weight infantsen
dc.typeArticleen
dc.identifier.journalLæknablaðiðen

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