Developmental psychopathology of children and adolescents with Tourette syndrome - impact of ADHD

2.50
Hdl Handle:
http://hdl.handle.net/2336/29392
Title:
Developmental psychopathology of children and adolescents with Tourette syndrome - impact of ADHD
Authors:
Roessner, Veit; Becker, Andreas; Banaschewski, Tobias; Freeman, Roger D; Rothenberger, Aribert; Hannesdottir, Helga; Tourette Syndrome International Database Consortium
Citation:
Eur Child Adolesc Psychiatry. 2007, 16 Suppl 1:24-35
Issue Date:
3-Jun-2007
Abstract:
BACKGROUND: In Tourette syndrome (TS) as a neurodevelopmental disorder not only the tics but also the comorbid conditions change with increasing age. ADHD is highly comorbid with TS and usually impairs psychosocial functioning more than the tics. Its impact on further comorbidity during development is important for clinical practice and still a matter of debate. METHOD: Aspects of developmental psychopathology considering the impact of ADHD were examined by logistic regression (year wisely) in a cross-sectional sample of children and adolescents (n = 5060) from the TIC database. RESULTS: In TS+ADHD (compared to TS-ADHD) higher rates of comorbid conditions like OCD, anxiety disorders, CD/ODD and mood disorders were found in children (5-10 years). In adolescents (11-17 years) higher comorbidity rates in TS+ADHD remained only for CD/ODD and mood disorders. Accordingly, for OCD and anxiety disorders there was a steeper year wise increase of these comorbidities in TS-ADHD while it was a similar for CD/ODD and mood disorders in TS-ADHD as well as TS+ADHD. CONCLUSION: Children with TS+ADHD have more comorbidities than the TS-ADHD group, whereas in both adolescent groups this did no longer hold for OCD and anxiety disorders. These findings indicate that in TS comorbid ADHD is associated with high rates of externalizing and internalizing problems, whereas TS without ADHD is associated only with internalizing problems in adolescence.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://dx.doi.org/10.1007/s00787-007-1004-6

Full metadata record

DC FieldValue Language
dc.contributor.authorRoessner, Veit-
dc.contributor.authorBecker, Andreas-
dc.contributor.authorBanaschewski, Tobias-
dc.contributor.authorFreeman, Roger D-
dc.contributor.authorRothenberger, Aribert-
dc.contributor.authorHannesdottir, Helga-
dc.contributor.authorTourette Syndrome International Database Consortium-
dc.date.accessioned2008-06-03T13:48:26Z-
dc.date.available2008-06-03T13:48:26Z-
dc.date.issued2007-06-03-
dc.date.submitted2008-06-03-
dc.identifier.citationEur Child Adolesc Psychiatry. 2007, 16 Suppl 1:24-35en
dc.identifier.issn1018-8827-
dc.identifier.pmid17665280-
dc.identifier.doi10.1007/s00787-007-1004-6-
dc.identifier.urihttp://hdl.handle.net/2336/29392-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractBACKGROUND: In Tourette syndrome (TS) as a neurodevelopmental disorder not only the tics but also the comorbid conditions change with increasing age. ADHD is highly comorbid with TS and usually impairs psychosocial functioning more than the tics. Its impact on further comorbidity during development is important for clinical practice and still a matter of debate. METHOD: Aspects of developmental psychopathology considering the impact of ADHD were examined by logistic regression (year wisely) in a cross-sectional sample of children and adolescents (n = 5060) from the TIC database. RESULTS: In TS+ADHD (compared to TS-ADHD) higher rates of comorbid conditions like OCD, anxiety disorders, CD/ODD and mood disorders were found in children (5-10 years). In adolescents (11-17 years) higher comorbidity rates in TS+ADHD remained only for CD/ODD and mood disorders. Accordingly, for OCD and anxiety disorders there was a steeper year wise increase of these comorbidities in TS-ADHD while it was a similar for CD/ODD and mood disorders in TS-ADHD as well as TS+ADHD. CONCLUSION: Children with TS+ADHD have more comorbidities than the TS-ADHD group, whereas in both adolescent groups this did no longer hold for OCD and anxiety disorders. These findings indicate that in TS comorbid ADHD is associated with high rates of externalizing and internalizing problems, whereas TS without ADHD is associated only with internalizing problems in adolescence.en
dc.language.isoenen
dc.publisherDr. Dietrich Steinkopff Verlagen
dc.relation.urlhttp://dx.doi.org/10.1007/s00787-007-1004-6en
dc.subject.meshAdolescenten
dc.subject.meshAdolescent Developmenten
dc.subject.meshAttention Deficit Disorder with Hyperactivityen
dc.subject.meshChilden
dc.subject.meshChild Developmenten
dc.subject.meshChild, Preschoolen
dc.subject.meshComorbidityen
dc.subject.meshCross-Sectional Studiesen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshMental Disordersen
dc.subject.meshRegression Analysisen
dc.subject.meshTourette Syndromeen
dc.titleDevelopmental psychopathology of children and adolescents with Tourette syndrome - impact of ADHDen
dc.typeArticleen
dc.contributor.departmentDept. of Child and Adolescent Psychiatry/Psychotherapy, University of Goettingen, Von-Siebold-Str. 5, 37075, Göttingen, Germany. vroessn@gwdg.deen
dc.identifier.journalEuropean child & adolescent psychiatryen

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