A clinical score predicting a brief and uneventful course of newly diagnosed idiopathic thrombocytopenic purpura in children.

2.50
Hdl Handle:
http://hdl.handle.net/2336/29716
Title:
A clinical score predicting a brief and uneventful course of newly diagnosed idiopathic thrombocytopenic purpura in children.
Authors:
Edslev, Pernille Wendtland; Rosthøj, Steen; Treutiger, Iris; Rajantie, Jukka; Zeller, Bernward; Jonsson, Olafur G
Citation:
Br. J. Haematol. 2007, 138(4):513-6
Issue Date:
1-Aug-2007
Abstract:
The Nordic idiopathic thrombocytopenic purpura study data showed that morbidity occurred mainly in children with thrombocytopenia lasting >3 months, whereas, the risk period with platelet counts <20 x 10(9)/l was short and the number of bleeding events low in children with shorter disease duration. These brief, uneventful courses were predicted by developing a scoring system based on six clinical features: abrupt onset (weight 5), age <10 years (3), preceding infection (2), platelet count <5 x 10(9)/l, wet purpura (1) and male gender (1). The score was derived and validated in two different cohorts of children. High scores (10-14) clearly identified low-risk patients. The score provides valid prognostic information and may be useful in clinical decision-making.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2141.2007.06682.x

Full metadata record

DC FieldValue Language
dc.contributor.authorEdslev, Pernille Wendtland-
dc.contributor.authorRosthøj, Steen-
dc.contributor.authorTreutiger, Iris-
dc.contributor.authorRajantie, Jukka-
dc.contributor.authorZeller, Bernward-
dc.contributor.authorJonsson, Olafur G-
dc.date.accessioned2008-06-09T13:54:09Z-
dc.date.available2008-06-09T13:54:09Z-
dc.date.issued2007-08-01-
dc.date.submitted2008-06-09-
dc.identifier.citationBr. J. Haematol. 2007, 138(4):513-6en
dc.identifier.issn0007-1048-
dc.identifier.pmid17608764-
dc.identifier.doi10.1111/j.1365-2141.2007.06682.x-
dc.identifier.urihttp://hdl.handle.net/2336/29716-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractThe Nordic idiopathic thrombocytopenic purpura study data showed that morbidity occurred mainly in children with thrombocytopenia lasting >3 months, whereas, the risk period with platelet counts <20 x 10(9)/l was short and the number of bleeding events low in children with shorter disease duration. These brief, uneventful courses were predicted by developing a scoring system based on six clinical features: abrupt onset (weight 5), age <10 years (3), preceding infection (2), platelet count <5 x 10(9)/l, wet purpura (1) and male gender (1). The score was derived and validated in two different cohorts of children. High scores (10-14) clearly identified low-risk patients. The score provides valid prognostic information and may be useful in clinical decision-making.en
dc.language.isoenen
dc.publisherBlackwell Scientific Publicationsen
dc.relation.urlhttp://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2141.2007.06682.xen
dc.subject.meshAge Factorsen
dc.subject.meshChilden
dc.subject.meshFemaleen
dc.subject.meshHealth Status Indicatorsen
dc.subject.meshHumansen
dc.subject.meshImmunoglobulins, Intravenousen
dc.subject.meshMaleen
dc.subject.meshOdds Ratioen
dc.subject.meshPlatelet Counten
dc.subject.meshPrognosisen
dc.subject.meshProspective Studiesen
dc.subject.meshPurpura, Thrombocytopenic, Idiopathicen
dc.subject.meshRisk Assessmenten
dc.subject.meshSex Factorsen
dc.titleA clinical score predicting a brief and uneventful course of newly diagnosed idiopathic thrombocytopenic purpura in children.en
dc.typeArticleen
dc.identifier.journalBritish journal of haematologyen

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