2.50
Hdl Handle:
http://hdl.handle.net/2336/3455
Title:
Iron status in 6-y-old children: associations with growth and earlier iron status
Authors:
Gunnarsson, B S; Thorsdottir, I; Palsson, G
Citation:
Eur J Clin Nutr 2005, 59(6):761-7
Issue Date:
2005
Abstract:
OBJECTIVE: To investigate the iron status of 6-y-old children and its association with growth and earlier iron status. DESIGN: In a cross-sectional study, children's body size measurements were recorded and blood samples taken near their sixth birthday. SUBJECTS: A sample of 188 children, randomly selected in two previous studies, was contacted, and 139(74%) agreed to participate. RESULTS: No children had iron deficiency anaemia, one was iron-deficient (serum ferritin (SF) <15 microg/l and mean corpuscular volume (MCV) <76 fl but 16% had depleted iron stores (SF<15 microg/l). Iron status indices were generally higher than at 1 and 2 y, but correlation was seen between iron status indices at 6 y and earlier values. Haemoglobin concentration at 6 y was negatively associated with length gain from birth to 1 y (B+/-s.e.=-1.269+/-0.452; P=0.007; adj. R2=0.119) (n=52), and proportional weight gain from birth to 1 y was higher among children with SF<15 microg/l at 6 y (295+/-33%; n=10) than those with SF> or =15 microg/l (258+/-31%; n=49) (P=0.001). MCV at 2 y predicted weight gain from 2 to 6 y (B+/-s.e.=1.721+/-0.581; P=0.005; adj. R2=0.153) (n=44); also, children with SF<15 microg/l at 6 y (n=9) gained 7.8+/-1.2 kg from 2 to 6 y, while children with SF> or =15 microg/l (n=35) gained 9.6+/-2.8 kg (P=0.007), furthermore a difference was seen in proportional weight gain from 2 to 6 y between children with depleted iron stores at 2 y and not, or 156+/-13 vs 169+/-18% (P=0.038). CONCLUSION: The results suggest that low iron status at 1 and 2 y might lead to slower growth up to 6 y of age. Low iron status at 1 and 2 y and/or slower growth from 1 and 2 y up to 6 y might contribute to worse iron status at 6 y, while faster growth in early childhood is related to lower iron status.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.nature.com/ejcn/journal/v59/n6/abs/1602137a.html

Full metadata record

DC FieldValue Language
dc.contributor.authorGunnarsson, B S-
dc.contributor.authorThorsdottir, I-
dc.contributor.authorPalsson, G-
dc.date.accessioned2006-07-14T12:05:38Z-
dc.date.available2006-07-14T12:05:38Z-
dc.date.issued2005-
dc.identifier.citationEur J Clin Nutr 2005, 59(6):761-7en
dc.identifier.issn0954-3007-
dc.identifier.pmid15931260-
dc.identifier.doi10.1038/sj.ejcn.1602137-
dc.identifier.otherNUR12en
dc.identifier.otherPED12en
dc.identifier.urihttp://hdl.handle.net/2336/3455-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractOBJECTIVE: To investigate the iron status of 6-y-old children and its association with growth and earlier iron status. DESIGN: In a cross-sectional study, children's body size measurements were recorded and blood samples taken near their sixth birthday. SUBJECTS: A sample of 188 children, randomly selected in two previous studies, was contacted, and 139(74%) agreed to participate. RESULTS: No children had iron deficiency anaemia, one was iron-deficient (serum ferritin (SF) <15 microg/l and mean corpuscular volume (MCV) <76 fl but 16% had depleted iron stores (SF<15 microg/l). Iron status indices were generally higher than at 1 and 2 y, but correlation was seen between iron status indices at 6 y and earlier values. Haemoglobin concentration at 6 y was negatively associated with length gain from birth to 1 y (B+/-s.e.=-1.269+/-0.452; P=0.007; adj. R2=0.119) (n=52), and proportional weight gain from birth to 1 y was higher among children with SF<15 microg/l at 6 y (295+/-33%; n=10) than those with SF> or =15 microg/l (258+/-31%; n=49) (P=0.001). MCV at 2 y predicted weight gain from 2 to 6 y (B+/-s.e.=1.721+/-0.581; P=0.005; adj. R2=0.153) (n=44); also, children with SF<15 microg/l at 6 y (n=9) gained 7.8+/-1.2 kg from 2 to 6 y, while children with SF> or =15 microg/l (n=35) gained 9.6+/-2.8 kg (P=0.007), furthermore a difference was seen in proportional weight gain from 2 to 6 y between children with depleted iron stores at 2 y and not, or 156+/-13 vs 169+/-18% (P=0.038). CONCLUSION: The results suggest that low iron status at 1 and 2 y might lead to slower growth up to 6 y of age. Low iron status at 1 and 2 y and/or slower growth from 1 and 2 y up to 6 y might contribute to worse iron status at 6 y, while faster growth in early childhood is related to lower iron status.en
dc.language.isoenen
dc.publisherNature Publishing Groupen
dc.relation.urlhttp://www.nature.com/ejcn/journal/v59/n6/abs/1602137a.htmlen
dc.subjectAnemia, Iron-Deficiencyen
dc.subjectBody Heighten
dc.subjectChilden
dc.subjectChild Developmenten
dc.subjectChild, Preschoolen
dc.subjectCross-Sectional Studiesen
dc.subjectErythrocyte Indicesen
dc.subjectFemaleen
dc.subjectHealth Statusen
dc.subjectHealth Surveysen
dc.subjectHumansen
dc.subjectInfanten
dc.subjectIronen
dc.subjectIron, Dietaryen
dc.subjectNutritional Statusen
dc.subjectResearch Support, Non-U.S. Gov'ten
dc.subjectWeight Gainen
dc.titleIron status in 6-y-old children: associations with growth and earlier iron statusen
dc.typeArticleen
dc.identifier.journalEuropean journal of clinical nutritionen
dc.format.digYES-

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