2.50
Hdl Handle:
http://hdl.handle.net/2336/34652
Title:
Serum immunoglobulinD in infants and children
Authors:
Haraldsson, A; Weemaes, C M; Jonasdottir, S; Olafsson, O; Van De Wiel, G; Goertz, J; Klasen, I
Citation:
Scand. J. Immunol. 2000, 51(4):415-8
Issue Date:
1-Apr-2000
Abstract:
Serum immunoglobulinD (IgD) concentration is usually low in healthy individuals as compared to other immunoglobulin classes. Most studies on serum IgD are concerned with serum levels in healthy adults but reference values for young children and infants are not easily available. In order to establish age specific reference values we measured IgD levels in serum of 184 healthy Icelandic children, age 0-14 years and 60 healthy blood donors age 18-63, using the ELISA technique. Special attention was paid to the youngest age groups. Results showed low IgD values in infants and young children, gradually increasing until the age of 10 but then decreasing with age. We conclude that IgD gradually increases with age in childhood as other immunoglobulin classes but later declines. These findings can be of importance in revealing the function of IgD in the immune system as well as in the diagnosis of the hyper-IgD syndrome.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
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Full metadata record

DC FieldValue Language
dc.contributor.authorHaraldsson, A-
dc.contributor.authorWeemaes, C M-
dc.contributor.authorJonasdottir, S-
dc.contributor.authorOlafsson, O-
dc.contributor.authorVan De Wiel, G-
dc.contributor.authorGoertz, J-
dc.contributor.authorKlasen, I-
dc.date.accessioned2008-08-07T09:22:51Z-
dc.date.available2008-08-07T09:22:51Z-
dc.date.issued2000-04-01-
dc.date.submitted2008-08-07-
dc.identifier.citationScand. J. Immunol. 2000, 51(4):415-8en
dc.identifier.issn0300-9475-
dc.identifier.pmid10736115-
dc.identifier.doi10.1046/j.1365-3083.2000.00702.x-
dc.identifier.urihttp://hdl.handle.net/2336/34652-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractSerum immunoglobulinD (IgD) concentration is usually low in healthy individuals as compared to other immunoglobulin classes. Most studies on serum IgD are concerned with serum levels in healthy adults but reference values for young children and infants are not easily available. In order to establish age specific reference values we measured IgD levels in serum of 184 healthy Icelandic children, age 0-14 years and 60 healthy blood donors age 18-63, using the ELISA technique. Special attention was paid to the youngest age groups. Results showed low IgD values in infants and young children, gradually increasing until the age of 10 but then decreasing with age. We conclude that IgD gradually increases with age in childhood as other immunoglobulin classes but later declines. These findings can be of importance in revealing the function of IgD in the immune system as well as in the diagnosis of the hyper-IgD syndrome.en
dc.language.isoenen
dc.publisherBlackwell Scientific Publicationsen
dc.relation.urlhttp://search.ebscohost.com/login.aspx?direct=true&db=aph&AN=5866655&site=ehost-liveen
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshAgingen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshEnzyme-Linked Immunosorbent Assayen
dc.subject.meshHumansen
dc.subject.meshImmunoglobulin Den
dc.subject.meshInfanten
dc.subject.meshInfant, Newbornen
dc.subject.meshMiddle Ageden
dc.subject.meshReference Valuesen
dc.titleSerum immunoglobulinD in infants and childrenen
dc.typeArticleen
dc.contributor.departmentDepartment of Paediatrics, University Hospital, Reykjavík, Iceland.en
dc.identifier.journalScandinavian journal of immunologyen

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