Obesity and nocturnal gastro-oesophageal reflux are related to onset of asthma and respiratory symptoms

2.50
Hdl Handle:
http://hdl.handle.net/2336/3468
Title:
Obesity and nocturnal gastro-oesophageal reflux are related to onset of asthma and respiratory symptoms
Authors:
Gunnbjornsdottir, M I; Omenaas, E; Gislason, T; Norrman, E; Olin, A C; Jõgi, R; Jensen, E J; Lindberg, E; Bjornsson, E; Franklin, K; Janson, C; Gulsvik, A; Laerum, B; Svanes, C; Torén, K; Tunsäter, A; Lillienberg, L; Gislason, D; Blondal, T; Bjornsdottir, U S; Jorundsdottir, K B; Talvik, R; Forsberg, B; Franklin, K; Lundbäck, B; Söderberg, M; Ledin, M C; Boman, G; Norbäck, D; Wieslander, G; Spetz-Nyström, U; Cashelunge, K Stenudd; Rydén, E
Citation:
Eur. Respir. J. 2004, 24(1):116-21
Issue Date:
2004
Abstract:
Several studies have identified obesity as a risk factor for asthma in both children and adults. An increased prevalence of asthma in subjects with gastro-oesophageal reflux (GOR) and obstructive sleep apnoea syndrome has also been reported. The aim of this investigation was to study obesity, nocturnal GOR and snoring as independent risk factors for onset of asthma and respiratory symptoms in a Nordic population. In a 5-10 yr follow-up study of the European Community Respiratory Health Survey in Iceland, Norway, Denmark, Sweden and Estonia, a postal questionnaire was sent to previous respondents. A total of 16,191 participants responded to the questionnaire. Reported onset of asthma, wheeze and night-time symptoms as well as nocturnal GOR and habitual snoring increased in prevalence along with the increase in body mass index (BMI). After adjusting for nocturnal GOR, habitual snoring and other confounders, obesity (BMI >30) remained significantly related to the onset of asthma, wheeze and night-time symptoms. Nocturnal GOR was independently related to the onset of asthma and in addition, both nocturnal GOR and habitual snoring were independently related to onset of wheeze and night-time symptoms. This study adds evidence to an independent relationship between obesity, nocturnal gastro-oesophageal reflux and habitual snoring and the onset of asthma and respiratory symptoms in adults.
Additional Links:
http://erj.ersjournals.com/cgi/content/full/24/1/116

Full metadata record

DC FieldValue Language
dc.contributor.authorGunnbjornsdottir, M I-
dc.contributor.authorOmenaas, E-
dc.contributor.authorGislason, T-
dc.contributor.authorNorrman, E-
dc.contributor.authorOlin, A C-
dc.contributor.authorJõgi, R-
dc.contributor.authorJensen, E J-
dc.contributor.authorLindberg, E-
dc.contributor.authorBjornsson, E-
dc.contributor.authorFranklin, K-
dc.contributor.authorJanson, C-
dc.contributor.authorGulsvik, A-
dc.contributor.authorLaerum, B-
dc.contributor.authorSvanes, C-
dc.contributor.authorTorén, K-
dc.contributor.authorTunsäter, A-
dc.contributor.authorLillienberg, L-
dc.contributor.authorGislason, D-
dc.contributor.authorBlondal, T-
dc.contributor.authorBjornsdottir, U S-
dc.contributor.authorJorundsdottir, K B-
dc.contributor.authorTalvik, R-
dc.contributor.authorForsberg, B-
dc.contributor.authorFranklin, K-
dc.contributor.authorLundbäck, B-
dc.contributor.authorSöderberg, M-
dc.contributor.authorLedin, M C-
dc.contributor.authorBoman, G-
dc.contributor.authorNorbäck, D-
dc.contributor.authorWieslander, G-
dc.contributor.authorSpetz-Nyström, U-
dc.contributor.authorCashelunge, K Stenudd-
dc.contributor.authorRydén, E-
dc.date.accessioned2006-07-17T10:49:49Z-
dc.date.available2006-07-17T10:49:49Z-
dc.date.issued2004-
dc.identifier.citationEur. Respir. J. 2004, 24(1):116-21en
dc.identifier.issn0903-1936-
dc.identifier.pmid15293613-
dc.identifier.urihttp://hdl.handle.net/2336/3468-
dc.description.abstractSeveral studies have identified obesity as a risk factor for asthma in both children and adults. An increased prevalence of asthma in subjects with gastro-oesophageal reflux (GOR) and obstructive sleep apnoea syndrome has also been reported. The aim of this investigation was to study obesity, nocturnal GOR and snoring as independent risk factors for onset of asthma and respiratory symptoms in a Nordic population. In a 5-10 yr follow-up study of the European Community Respiratory Health Survey in Iceland, Norway, Denmark, Sweden and Estonia, a postal questionnaire was sent to previous respondents. A total of 16,191 participants responded to the questionnaire. Reported onset of asthma, wheeze and night-time symptoms as well as nocturnal GOR and habitual snoring increased in prevalence along with the increase in body mass index (BMI). After adjusting for nocturnal GOR, habitual snoring and other confounders, obesity (BMI >30) remained significantly related to the onset of asthma, wheeze and night-time symptoms. Nocturnal GOR was independently related to the onset of asthma and in addition, both nocturnal GOR and habitual snoring were independently related to onset of wheeze and night-time symptoms. This study adds evidence to an independent relationship between obesity, nocturnal gastro-oesophageal reflux and habitual snoring and the onset of asthma and respiratory symptoms in adults.en
dc.language.isoenen
dc.publisherManey Publishing (for the European Respiratory Society)en
dc.relation.urlhttp://erj.ersjournals.com/cgi/content/full/24/1/116en
dc.subjectAdulten
dc.subjectAge Distributionen
dc.subjectAnalysis of Varianceen
dc.subjectAsthmaen
dc.subjectChi-Square Distributionen
dc.subjectCircadian Rhythmen
dc.subjectComorbidityen
dc.subjectComparative Studyen
dc.subjectEuropeen
dc.subjectFemaleen
dc.subjectGastroesophageal Refluxen
dc.subjectHealth Surveysen
dc.subjectHumansen
dc.subjectIncidenceen
dc.subjectLogistic Modelsen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectObesityen
dc.subjectPrognosisen
dc.subjectQuestionnairesen
dc.subjectResearch Support, Non-U.S. Gov'ten
dc.subjectRisk Assessmenten
dc.subjectSeverity of Illness Indexen
dc.subjectSex Distributionen
dc.subjectSnoring/diagnosis/*epidemiologyen
dc.subject.otherRitrýnd greinen
dc.subject.otherPeer revieweden
dc.titleObesity and nocturnal gastro-oesophageal reflux are related to onset of asthma and respiratory symptomsen
dc.typeArticleen
dc.format.digYES-

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