A diet rich in long chain omega-3 fatty acids modulates satiety in overweight and obese volunteers during weight loss

2.50
Hdl Handle:
http://hdl.handle.net/2336/42096
Title:
A diet rich in long chain omega-3 fatty acids modulates satiety in overweight and obese volunteers during weight loss
Authors:
Parra, Dolores; Ramel, Alfons; Bandarra, Narcisa; Kiely, Mairead; Martínez, J Alfredo; Thorsdottir, Inga
Citation:
Appetite. 2008, 51(3):676-80
Issue Date:
1-Nov-2008
Abstract:
Long chain omega-3 fatty acids (LC n-3 FA) are considered nutritional factors with a potential to modulate food intake. Thus, the aim of the current study was to determine whether appetite could be affected by LC n-3 FA when included in a calorie-restricted diet to treat overweight or obesity. Appetite was explored in volunteers (31+/-5 years; BMI: 28.3+/-1.5 kg/m(2)) during the last 2 weeks of an 8-week energy-restricted balanced diet (weight loss=-5.9+/-3.1%) providing either a low (<260 mg/day; n=112) or a high amount (>1300 mg/day; n=121) of LC n-3 FA. Erythrocyte membrane fatty acids were measured to detect diet-related changes in fatty acids and a validated visual analogue scale (VAS) was used to measure hunger sensations directly after and 2h after a test dinner. The LC n-3 FA content in erythrocyte membrane was lower in the low LC n-3 FA group (10.5+/-2.5% vs. 12.5+/-2.6%; p<0.001) after the intervention. The VAS assessment revealed lower hunger sensations in the high LC n-3 FA group immediately after the test dinner (fullness: p=0.045) and after 120 min (fullness: p=0.008; hunger: p=0.039). Correlation analysis showed a positive relation between n-3 FA/n-6 FA ratio in erythrocyte membrane and fullness 2h postprandial (r=0.139; p=0.032). In conclusion, LC n-3 FA intake modulates postprandial satiety in overweight and obese volunteers during weight loss. Further research is needed to investigate whether LC n-3 FA improve compliance to the nutritional treatment of overweight and obesity as well as weight loss maintenance.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.sciencedirect.com/science/article/B6WB2-4SRW0YS-1/2/be96ea01006a099d8b389c66b097f020

Full metadata record

DC FieldValue Language
dc.contributor.authorParra, Dolores-
dc.contributor.authorRamel, Alfons-
dc.contributor.authorBandarra, Narcisa-
dc.contributor.authorKiely, Mairead-
dc.contributor.authorMartínez, J Alfredo-
dc.contributor.authorThorsdottir, Inga-
dc.date.accessioned2008-12-09T11:10:33Z-
dc.date.available2008-12-09T11:10:33Z-
dc.date.issued2008-11-01-
dc.date.submitted2008-12-09-
dc.identifier.citationAppetite. 2008, 51(3):676-80en
dc.identifier.issn0195-6663-
dc.identifier.pmid18602429-
dc.identifier.doi10.1016/j.appet.2008.06.003-
dc.identifier.urihttp://hdl.handle.net/2336/42096-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractLong chain omega-3 fatty acids (LC n-3 FA) are considered nutritional factors with a potential to modulate food intake. Thus, the aim of the current study was to determine whether appetite could be affected by LC n-3 FA when included in a calorie-restricted diet to treat overweight or obesity. Appetite was explored in volunteers (31+/-5 years; BMI: 28.3+/-1.5 kg/m(2)) during the last 2 weeks of an 8-week energy-restricted balanced diet (weight loss=-5.9+/-3.1%) providing either a low (<260 mg/day; n=112) or a high amount (>1300 mg/day; n=121) of LC n-3 FA. Erythrocyte membrane fatty acids were measured to detect diet-related changes in fatty acids and a validated visual analogue scale (VAS) was used to measure hunger sensations directly after and 2h after a test dinner. The LC n-3 FA content in erythrocyte membrane was lower in the low LC n-3 FA group (10.5+/-2.5% vs. 12.5+/-2.6%; p<0.001) after the intervention. The VAS assessment revealed lower hunger sensations in the high LC n-3 FA group immediately after the test dinner (fullness: p=0.045) and after 120 min (fullness: p=0.008; hunger: p=0.039). Correlation analysis showed a positive relation between n-3 FA/n-6 FA ratio in erythrocyte membrane and fullness 2h postprandial (r=0.139; p=0.032). In conclusion, LC n-3 FA intake modulates postprandial satiety in overweight and obese volunteers during weight loss. Further research is needed to investigate whether LC n-3 FA improve compliance to the nutritional treatment of overweight and obesity as well as weight loss maintenance.en
dc.language.isoenen
dc.publisherAcademic Pressen
dc.relation.urlhttp://www.sciencedirect.com/science/article/B6WB2-4SRW0YS-1/2/be96ea01006a099d8b389c66b097f020en
dc.subject.meshPubMed - in processen
dc.titleA diet rich in long chain omega-3 fatty acids modulates satiety in overweight and obese volunteers during weight lossen
dc.typeArticleen
dc.identifier.eissn1095-8304-
dc.contributor.departmentThe Department of Physiology and Nutrition, University of Navarra, C/Irunlarrea s/n, Pamplona, Spain.en
dc.identifier.journalAppetiteen

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