2.50
Hdl Handle:
http://hdl.handle.net/2336/4580
Title:
Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study
Authors:
Jonasson, F; Damji, K F; Arnarsson, A; Sverrisson, T; Wang, L; Sasaki, H; Sasaki, K
Citation:
Eye 2003, 17(6):747-53
Issue Date:
1-Aug-2003
Abstract:
PURPOSE: To establish the age- and sex-specific prevalence of open-angle glaucoma (OAG) subsuming pseudoexfoliation (PEX) in the city of Reykjavik. METHODS: Participants 50 years of age and older who were part of the Reykjavik Eye Study and classified as having glaucoma were divided into three categories:Category 1: two or more of the following based on optic nerve stereophotograph reading: vertical cup to disc ratio (VCDR) 97.5th percentile (>0.7), focal glaucomatous disc change, C/D asymmetry of 97.5th percentile difference between eyes (>0.2) as well as glaucomatous visual field defect (GVFD).Category 2: 99.5th percentile of VCDR (>0.8) and 99.5% percentile difference between eyes (>/=0.3), without a GVFD.Category 3: VA<3/60 and IOP>99.5th percentile or VA <3/60 and evidence of filtering surgery. For a glaucoma suspect, one of the following was present: VCDR>99.5th percentile (>0.8), focal glaucomatous disc change, C/D asymmetry of 99.5th percentile (> or =0.3), GVFD only, IOP> or =23 mmHg (97.5 percentile). PEX was diagnosed by the presence of a central shield and/or a peripheral band on the anterior lens capsule. RESULTS: Of 42 persons (22 males and 20 females) with OAG, 13 (31.0%) had PEX. The minimum prevalence of OAG was 4.0% (42/1045) (95% CI 2.8-5.2) for those 50 years and older and 10.3% (95% CI 8.5-12.2) for PEX. The prevalence of OAG increases with age (OR=1.10/year, 95% CI 1.07-1.13, P=0.000) and the same applies for the prevalence of PEX, OR=1.10 (95% CI 1.07-1.12, P=0.000). CONCLUSION: There is a 10% annual increase for both OAG and PEX in persons 50 years and older.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.nature.com/eye/journal/v17/n6/full/6700374a.html

Full metadata record

DC FieldValue Language
dc.contributor.authorJonasson, F-
dc.contributor.authorDamji, K F-
dc.contributor.authorArnarsson, A-
dc.contributor.authorSverrisson, T-
dc.contributor.authorWang, L-
dc.contributor.authorSasaki, H-
dc.contributor.authorSasaki, K-
dc.date.accessioned2006-09-22T16:05:16Z-
dc.date.available2006-09-22T16:05:16Z-
dc.date.issued2003-08-01-
dc.identifier.citationEye 2003, 17(6):747-53en
dc.identifier.issn0950-222X-
dc.identifier.pmid12928689-
dc.identifier.doi10.1038/sj.eye.6700374-
dc.identifier.otherOPH12-
dc.identifier.urihttp://hdl.handle.net/2336/4580-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractPURPOSE: To establish the age- and sex-specific prevalence of open-angle glaucoma (OAG) subsuming pseudoexfoliation (PEX) in the city of Reykjavik. METHODS: Participants 50 years of age and older who were part of the Reykjavik Eye Study and classified as having glaucoma were divided into three categories:Category 1: two or more of the following based on optic nerve stereophotograph reading: vertical cup to disc ratio (VCDR) 97.5th percentile (>0.7), focal glaucomatous disc change, C/D asymmetry of 97.5th percentile difference between eyes (>0.2) as well as glaucomatous visual field defect (GVFD).Category 2: 99.5th percentile of VCDR (>0.8) and 99.5% percentile difference between eyes (>/=0.3), without a GVFD.Category 3: VA<3/60 and IOP>99.5th percentile or VA <3/60 and evidence of filtering surgery. For a glaucoma suspect, one of the following was present: VCDR>99.5th percentile (>0.8), focal glaucomatous disc change, C/D asymmetry of 99.5th percentile (> or =0.3), GVFD only, IOP> or =23 mmHg (97.5 percentile). PEX was diagnosed by the presence of a central shield and/or a peripheral band on the anterior lens capsule. RESULTS: Of 42 persons (22 males and 20 females) with OAG, 13 (31.0%) had PEX. The minimum prevalence of OAG was 4.0% (42/1045) (95% CI 2.8-5.2) for those 50 years and older and 10.3% (95% CI 8.5-12.2) for PEX. The prevalence of OAG increases with age (OR=1.10/year, 95% CI 1.07-1.13, P=0.000) and the same applies for the prevalence of PEX, OR=1.10 (95% CI 1.07-1.12, P=0.000). CONCLUSION: There is a 10% annual increase for both OAG and PEX in persons 50 years and older.en
dc.language.isoenen
dc.publisherNature Publishing Groupen
dc.relation.urlhttp://www.nature.com/eye/journal/v17/n6/full/6700374a.htmlen
dc.subject.meshAge Distributionen
dc.subject.meshAgeden
dc.subject.meshExfoliation Syndromeen
dc.subject.meshFemaleen
dc.subject.meshGlaucoma, Open-Angleen
dc.subject.meshHumansen
dc.subject.meshIceland/epidemiologyen
dc.subject.meshMiddle Ageden
dc.subject.meshPrevalenceen
dc.subject.meshResearch Support, Non-U.S. Gov'ten
dc.subject.meshSeverity of Illness Indexen
dc.subject.meshSex Distributionen
dc.subject.meshVisual Acuityen
dc.titlePrevalence of open-angle glaucoma in Iceland: Reykjavik Eye Studyen
dc.typeArticleen
dc.identifier.journalEye (London, England)en
dc.format.digYES-

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