Cosmic radiation and cancer mortality among airline pilots: results from a European cohort study (ESCAPE).

2.50
Hdl Handle:
http://hdl.handle.net/2336/48793
Title:
Cosmic radiation and cancer mortality among airline pilots: results from a European cohort study (ESCAPE).
Authors:
Langner, I; Blettner, M; Gundestrup, M; Storm, H; Aspholm, R; Auvinen, A; Pukkala, E; Hammer, G P; Zeeb, H; Hrafnkelsson, J; Rafnsson, V; Tulinius, H; De Angelis, G; Verdecchia, A; Haldorsen, T; Tveten, U; Eliasch, H; Hammar, N; Linnersjö, A
Citation:
Radiat Environ Biophys 2004, 42(4):247-56
Issue Date:
5-Feb-2004
Abstract:
Cosmic radiation is an occupational risk factor for commercial aircrews. In this large European cohort study (ESCAPE) its association with cancer mortality was investigated on the basis of individual effective dose estimates for 19,184 male pilots. Mean annual doses were in the range of 2-5 mSv and cumulative lifetime doses did not exceed 80 mSv. All-cause and all-cancer mortality was low for all exposure categories. A significant negative risk trend for all-cause mortality was seen with increasing dose. Neither external and internal comparisons nor nested case-control analyses showed any substantially increased risks for cancer mortality due to ionizing radiation. However, the number of deaths for specific types of cancer was low and the confidence intervals of the risk estimates were rather wide. Difficulties in interpreting mortality risk estimates for time-dependent exposures are discussed.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.springerlink.com/content/32vvxp56ntcneyq7

Full metadata record

DC FieldValue Language
dc.contributor.authorLangner, I-
dc.contributor.authorBlettner, M-
dc.contributor.authorGundestrup, M-
dc.contributor.authorStorm, H-
dc.contributor.authorAspholm, R-
dc.contributor.authorAuvinen, A-
dc.contributor.authorPukkala, E-
dc.contributor.authorHammer, G P-
dc.contributor.authorZeeb, H-
dc.contributor.authorHrafnkelsson, J-
dc.contributor.authorRafnsson, V-
dc.contributor.authorTulinius, H-
dc.contributor.authorDe Angelis, G-
dc.contributor.authorVerdecchia, A-
dc.contributor.authorHaldorsen, T-
dc.contributor.authorTveten, U-
dc.contributor.authorEliasch, H-
dc.contributor.authorHammar, N-
dc.contributor.authorLinnersjö, A-
dc.date.accessioned2009-02-10T09:22:32Z-
dc.date.available2009-02-10T09:22:32Z-
dc.date.issued2004-02-05-
dc.date.submitted2009-02-10-
dc.identifier.citationRadiat Environ Biophys 2004, 42(4):247-56en
dc.identifier.issn0301-634X-
dc.identifier.pmid14648170-
dc.identifier.doi10.1007/s00411-003-0214-7-
dc.identifier.urihttp://hdl.handle.net/2336/48793-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractCosmic radiation is an occupational risk factor for commercial aircrews. In this large European cohort study (ESCAPE) its association with cancer mortality was investigated on the basis of individual effective dose estimates for 19,184 male pilots. Mean annual doses were in the range of 2-5 mSv and cumulative lifetime doses did not exceed 80 mSv. All-cause and all-cancer mortality was low for all exposure categories. A significant negative risk trend for all-cause mortality was seen with increasing dose. Neither external and internal comparisons nor nested case-control analyses showed any substantially increased risks for cancer mortality due to ionizing radiation. However, the number of deaths for specific types of cancer was low and the confidence intervals of the risk estimates were rather wide. Difficulties in interpreting mortality risk estimates for time-dependent exposures are discussed.en
dc.language.isoenen
dc.publisherSpringer-Verlagen
dc.relation.urlhttp://www.springerlink.com/content/32vvxp56ntcneyq7en
dc.subject.meshAdulten
dc.subject.meshAerospace Medicineen
dc.subject.meshAircraften
dc.subject.meshCase-Control Studiesen
dc.subject.meshCause of Deathen
dc.subject.meshCohort Studiesen
dc.subject.meshCosmic Radiationen
dc.subject.meshEuropeen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshNeoplasmsen
dc.subject.meshNeoplasms, Radiation-Induceden
dc.subject.meshOccupational Exposureen
dc.subject.meshPoisson Distributionen
dc.subject.meshRadiometryen
dc.subject.meshRisk Assessmenten
dc.titleCosmic radiation and cancer mortality among airline pilots: results from a European cohort study (ESCAPE).en
dc.typeArticleen
dc.contributor.departmentSchool of Public Health, Division of Epidemiology and Medical Statistics, University of Bielefeld, P.O. Box 100 131, 33501 Bielefeld, Germany. Ingo.Langner@uni-bielefeld.deen
dc.identifier.journalRadiation and environmental biophysicsen

Related articles on PubMed

All Items in Hirsla are protected by copyright, with all rights reserved, unless otherwise indicated.