Pneumococcal serotype 19F conjugate vaccine induces cross-protective immunity to serotype 19A in a murine pneumococcal pneumonia model.

2.50
Hdl Handle:
http://hdl.handle.net/2336/5545
Title:
Pneumococcal serotype 19F conjugate vaccine induces cross-protective immunity to serotype 19A in a murine pneumococcal pneumonia model.
Authors:
Jakobsen, Håvard; Sigurdsson, Viktor D; Sigurdardottir, Sigurveig; Schulz, Dominique; Jonsdottir, Ingileif
Citation:
Infect. Immun. 2003, 71(5):2956-9
Issue Date:
1-May-2003
Abstract:
Immunization with a pneumococcal conjugate vaccine (PNC) containing serotype 19F induces cross-reactive antibodies to 19A in mice and human infants. Active immunization with PNC and passive immunization with serum samples from infants vaccinated with PNC containing serotype 19F, but not serotype 19A, protected against lung infection caused by both serotypes in a murine model.
Additional Links:
http://iai.asm.org/cgi/content/full/71/5/2956?view=long&pmid=12704178

Full metadata record

DC FieldValue Language
dc.contributor.authorJakobsen, Håvard-
dc.contributor.authorSigurdsson, Viktor D-
dc.contributor.authorSigurdardottir, Sigurveig-
dc.contributor.authorSchulz, Dominique-
dc.contributor.authorJonsdottir, Ingileif-
dc.date.accessioned2006-10-24T09:34:34Z-
dc.date.available2006-10-24T09:34:34Z-
dc.date.issued2003-05-01-
dc.identifier.citationInfect. Immun. 2003, 71(5):2956-9en
dc.identifier.issn0019-9567-
dc.identifier.pmid12704178-
dc.identifier.doi10.1128/IAI.71.5.2956-2959.2003-
dc.identifier.otherAAI12-
dc.identifier.urihttp://hdl.handle.net/2336/5545-
dc.description.abstractImmunization with a pneumococcal conjugate vaccine (PNC) containing serotype 19F induces cross-reactive antibodies to 19A in mice and human infants. Active immunization with PNC and passive immunization with serum samples from infants vaccinated with PNC containing serotype 19F, but not serotype 19A, protected against lung infection caused by both serotypes in a murine model.en
dc.language.isoenen
dc.publisherAmerican Society For Microbiologyen
dc.relation.urlhttp://iai.asm.org/cgi/content/full/71/5/2956?view=long&pmid=12704178en
dc.subject.meshAnimalsen
dc.subject.meshAntibodies, Bacterialen
dc.subject.meshHumansen
dc.subject.meshImmunization, Passiveen
dc.subject.meshInfanten
dc.subject.meshMiceen
dc.subject.meshPneumococcal Vaccinesen
dc.subject.meshPneumonia, Pneumococcalen
dc.subject.meshSerotypingen
dc.subject.meshStreptococcus pneumoniaeen
dc.subject.meshVaccinationen
dc.subject.meshVaccines, Conjugateen
dc.titlePneumococcal serotype 19F conjugate vaccine induces cross-protective immunity to serotype 19A in a murine pneumococcal pneumonia model.en
dc.typeArticleen
dc.identifier.journalInfection and immunityen
dc.format.digYES-

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