2.50
Hdl Handle:
http://hdl.handle.net/2336/6161
Title:
Seroprevalence of Toxoplasma gondii in Sweden, Estonia and Iceland
Authors:
Birgisdottir, Alda; Asbjornsdottir, Hulda; Cook, Elisabet; Gislason, David; Jansson, Christer; Olafsson, Isleifur; Gislason, Thorarinn; Jogi, Rain; Thjodleifsson, Bjarni
Citation:
Scand J Infect Dis. 2006, 38(8):625-31
Issue Date:
2006
Abstract:
Toxoplasmosis is a disease caused by the intracellular protozoan parasite, Toxoplasma gondii which infects up to one-third of the world human population. Toxoplasmosis in neonates and immunocompromised patients can lead to severe disease and death. We investigated the prevalence and risk factors for T. gondii infection in Iceland, Sweden and Estonia, and tested the hypothesis that T. gondii infection causes systemic inflammation and protects against atopy. Blood samples were collected from 1277 randomly selected subjects. The presence of T. gondii IgG antibodies was determined by an ELISA method and levels of Hs-CRP by immunoturbidimetric assay. The prevalence of T. gondii antibodies was 54.9% in Tartu, 23% in Uppsala and 9.8% in Reykjavik (p<0.0001). The risk of positive T. gondii antibodies increased with the number of siblings and with age in Sweden. T. gondii infection was associated with asthma related symptoms and increased Hs-CRP (p = 0.02). No association was found with IgE-sensitization and lung function. We concluded that risk factors for T. gondii infection suggested that soil exposure was 1 of the mechanisms in all 3 countries and a meat-associated infection route is a risk in Sweden.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://dx.doi.org/10.1080/00365540600606556

Full metadata record

DC FieldValue Language
dc.contributor.authorBirgisdottir, Alda-
dc.contributor.authorAsbjornsdottir, Hulda-
dc.contributor.authorCook, Elisabet-
dc.contributor.authorGislason, David-
dc.contributor.authorJansson, Christer-
dc.contributor.authorOlafsson, Isleifur-
dc.contributor.authorGislason, Thorarinn-
dc.contributor.authorJogi, Rain-
dc.contributor.authorThjodleifsson, Bjarni-
dc.date.accessioned2006-11-20T14:06:17Z-
dc.date.available2006-11-20T14:06:17Z-
dc.date.issued2006-
dc.date.submitted2006-11-20-
dc.identifier.citationScand J Infect Dis. 2006, 38(8):625-31en
dc.identifier.issn0036-5548-
dc.identifier.pmid16857606-
dc.identifier.doi10.1080/00365540600606556-
dc.identifier.otherGAS12en
dc.identifier.urihttp://hdl.handle.net/2336/6161-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractToxoplasmosis is a disease caused by the intracellular protozoan parasite, Toxoplasma gondii which infects up to one-third of the world human population. Toxoplasmosis in neonates and immunocompromised patients can lead to severe disease and death. We investigated the prevalence and risk factors for T. gondii infection in Iceland, Sweden and Estonia, and tested the hypothesis that T. gondii infection causes systemic inflammation and protects against atopy. Blood samples were collected from 1277 randomly selected subjects. The presence of T. gondii IgG antibodies was determined by an ELISA method and levels of Hs-CRP by immunoturbidimetric assay. The prevalence of T. gondii antibodies was 54.9% in Tartu, 23% in Uppsala and 9.8% in Reykjavik (p<0.0001). The risk of positive T. gondii antibodies increased with the number of siblings and with age in Sweden. T. gondii infection was associated with asthma related symptoms and increased Hs-CRP (p = 0.02). No association was found with IgE-sensitization and lung function. We concluded that risk factors for T. gondii infection suggested that soil exposure was 1 of the mechanisms in all 3 countries and a meat-associated infection route is a risk in Sweden.en
dc.language.isoenen
dc.relation.urlhttp://dx.doi.org/10.1080/00365540600606556en
dc.subject.meshAdulten
dc.subject.meshAnimalsen
dc.subject.meshAsthmaen
dc.subject.meshC-Reactive Proteinen
dc.subject.meshCatsen
dc.subject.meshEstonia/epidemiologyen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshHypersensitivityen
dc.subject.meshIceland/epidemiologyen
dc.subject.meshImmunoglobulin Een
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshResearch Support, Non-U.S. Gov'ten
dc.subject.meshRisk Factorsen
dc.subject.meshSeroepidemiologic Studiesen
dc.subject.meshSweden/epidemiologyen
dc.subject.meshToxoplasmaen
dc.subject.meshToxoplasmosisen
dc.titleSeroprevalence of Toxoplasma gondii in Sweden, Estonia and Icelanden
dc.typeManuscripten
dc.format.digYES-

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