Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity

2.50
Hdl Handle:
http://hdl.handle.net/2336/6342
Title:
Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity
Authors:
Gudmundsson, Gunnar; Gislason, Thorarinn; Lindberg, Eva; Hallin, Runa; Ulrik, Charlotte Suppli; Brøndum, Eva; Nieminen, Markku M; Aine, Tiina; Bakke, Per; Janson, Christer
Citation:
Respir. Res. 2006, 7:109
Issue Date:
16-Sep-2006
Abstract:
BACKGROUND: The aim of this study was to analyse mortality and associated risk factors, with special emphasis on health status, medications and co-morbidity, in patients with chronic obstructive pulmonary disease (COPD) that had been hospitalized for acute exacerbation. METHODS: This prospective study included 416 patients from each of the five Nordic countries that were followed for 24 months. The St. George's Respiratory Questionnaire (SGRQ) was administered. Information on treatment and co-morbidity was obtained. RESULTS: During the follow-up 122 (29.3%) of the 416 patients died. Patients with diabetes had an increased mortality rate [HR = 2.25 (1.28-3.95)]. Other risk factors were advanced age, low FEV1 and lower health status. Patients treated with inhaled corticosteroids and/or long-acting beta-2-agonists had a lower risk of death than patients using neither of these types of treatment. CONCLUSION: Mortality was high after COPD admission, with older age, decreased lung function, lower health status and diabetes the most important risk factors. Treatment with inhaled corticosteroids and long-acting bronchodilators may be associated with lower mortality in patients with COPD.
Description:
To access full text version of this article. Please click on the hyperlink "Full Text" at the bottom of this page
Additional Links:
http://respiratory-research.com/content/7/1/109

Full metadata record

DC FieldValue Language
dc.contributor.authorGudmundsson, Gunnar-
dc.contributor.authorGislason, Thorarinn-
dc.contributor.authorLindberg, Eva-
dc.contributor.authorHallin, Runa-
dc.contributor.authorUlrik, Charlotte Suppli-
dc.contributor.authorBrøndum, Eva-
dc.contributor.authorNieminen, Markku M-
dc.contributor.authorAine, Tiina-
dc.contributor.authorBakke, Per-
dc.contributor.authorJanson, Christer-
dc.date.accessioned2006-12-04T11:35:30Z-
dc.date.available2006-12-04T11:35:30Z-
dc.date.issued2006-09-16-
dc.date.submitted2006-12-04-
dc.identifier.citationRespir. Res. 2006, 7:109en
dc.identifier.issn1465-993X-
dc.identifier.pmid16914029-
dc.identifier.doi10.1186/1465-9921-7-109-
dc.identifier.otherPAD12-
dc.identifier.otherAAI12-
dc.identifier.urihttp://hdl.handle.net/2336/6342-
dc.descriptionTo access full text version of this article. Please click on the hyperlink "Full Text" at the bottom of this pageen
dc.description.abstractBACKGROUND: The aim of this study was to analyse mortality and associated risk factors, with special emphasis on health status, medications and co-morbidity, in patients with chronic obstructive pulmonary disease (COPD) that had been hospitalized for acute exacerbation. METHODS: This prospective study included 416 patients from each of the five Nordic countries that were followed for 24 months. The St. George's Respiratory Questionnaire (SGRQ) was administered. Information on treatment and co-morbidity was obtained. RESULTS: During the follow-up 122 (29.3%) of the 416 patients died. Patients with diabetes had an increased mortality rate [HR = 2.25 (1.28-3.95)]. Other risk factors were advanced age, low FEV1 and lower health status. Patients treated with inhaled corticosteroids and/or long-acting beta-2-agonists had a lower risk of death than patients using neither of these types of treatment. CONCLUSION: Mortality was high after COPD admission, with older age, decreased lung function, lower health status and diabetes the most important risk factors. Treatment with inhaled corticosteroids and long-acting bronchodilators may be associated with lower mortality in patients with COPD.en
dc.language.isoenen
dc.publisherBioMed Central Ltden
dc.relation.urlhttp://respiratory-research.com/content/7/1/109en
dc.subject.meshAge Distributionen
dc.subject.meshAgeden
dc.subject.meshAged, 80 and overen
dc.subject.meshComorbidityen
dc.subject.meshDiabetes Mellitusen
dc.subject.meshEurope/epidemiologyen
dc.subject.meshFemaleen
dc.subject.meshFollow-Up Studiesen
dc.subject.meshHumansen
dc.subject.meshIncidenceen
dc.subject.meshMaleen
dc.subject.meshPatient Dischargeen
dc.subject.meshPulmonary Disease, Chronic Obstructiveen
dc.subject.meshResearch Support, Non-U.S. Gov'ten
dc.subject.meshRisk Assessmenten
dc.subject.meshRisk Factorsen
dc.subject.meshSex Distributionen
dc.subject.meshSurvival Analysisen
dc.subject.meshSurvival Rateen
dc.titleMortality in COPD patients discharged from hospital: the role of treatment and co-morbidityen
dc.typeArticleen
dc.identifier.journalRespiratory researchen
dc.format.digYES-

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