Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia

2.50
Hdl Handle:
http://hdl.handle.net/2336/6444
Title:
Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia
Authors:
Birgisdottir, B E; Hill, J P; Thorsson, A V; Thorsdottir, I
Citation:
Ann. Nutr. Metab. 2006, 50(3):177-83
Issue Date:
1-May-2006
Abstract:
AIM: To compare the consumption of the cow milk proteins A1 and B beta-casein among children and adolescents in Iceland and Scandinavia (Norway, Denmark, Sweden and Finland) as this might explain the lower incidence of type 1 diabetes (per 100,000/year, 0-14 years) in Iceland. METHODS: The consumption of A1 beta-casein in each country among 2- and 11- to 14-year-old children was calculated from results on food intake and on cow milk protein concentration. The consumption values were then compared and evaluated against the incidence of type 1 diabetes. RESULTS: There was a significant difference between the consumption of A1 (p = 0.034) as well as the sum of A1 and B (p = 0.021) beta-casein in Iceland and Scandinavia for 2-year-old children. In the same age group, consumption of A1 beta-casein correlated with the incidence of type 1 diabetes in the countries (r = 0.9; p = 0.037). No significant difference in consumption of A1 or the sum of A1 and B beta-casein was found for 11- to 14-year-old adolescents. CONCLUSION: This study supports that lower consumption of A1 beta-casein might be related to the lower incidence of type 1 diabetes in Iceland than in Scandinavia. Additionally it indicates that consumption in young childhood might be of more importance for the development of the disease incidence than consumption in adolescence.
Description:
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Full metadata record

DC FieldValue Language
dc.contributor.authorBirgisdottir, B E-
dc.contributor.authorHill, J P-
dc.contributor.authorThorsson, A V-
dc.contributor.authorThorsdottir, I-
dc.date.accessioned2006-12-07T09:25:48Z-
dc.date.available2006-12-07T09:25:48Z-
dc.date.issued2006-05-01-
dc.date.submitted2006-12-07-
dc.identifier.citationAnn. Nutr. Metab. 2006, 50(3):177-83en
dc.identifier.issn0250-6807-
dc.identifier.pmid16407643-
dc.identifier.doi10.1159/000090738-
dc.identifier.otherNUR12-
dc.identifier.otherPED12-
dc.identifier.urihttp://hdl.handle.net/2336/6444-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractAIM: To compare the consumption of the cow milk proteins A1 and B beta-casein among children and adolescents in Iceland and Scandinavia (Norway, Denmark, Sweden and Finland) as this might explain the lower incidence of type 1 diabetes (per 100,000/year, 0-14 years) in Iceland. METHODS: The consumption of A1 beta-casein in each country among 2- and 11- to 14-year-old children was calculated from results on food intake and on cow milk protein concentration. The consumption values were then compared and evaluated against the incidence of type 1 diabetes. RESULTS: There was a significant difference between the consumption of A1 (p = 0.034) as well as the sum of A1 and B (p = 0.021) beta-casein in Iceland and Scandinavia for 2-year-old children. In the same age group, consumption of A1 beta-casein correlated with the incidence of type 1 diabetes in the countries (r = 0.9; p = 0.037). No significant difference in consumption of A1 or the sum of A1 and B beta-casein was found for 11- to 14-year-old adolescents. CONCLUSION: This study supports that lower consumption of A1 beta-casein might be related to the lower incidence of type 1 diabetes in Iceland than in Scandinavia. Additionally it indicates that consumption in young childhood might be of more importance for the development of the disease incidence than consumption in adolescence.en
dc.language.isoenen
dc.publisherKargeren
dc.relation.urlhttp://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=90738&Ausgabe=231622&ProduktNr=223977&filename=90738.pdfen
dc.subject.meshAdolescenten
dc.subject.meshAge Factorsen
dc.subject.meshAnimalsen
dc.subject.meshCaseinsen
dc.subject.meshCattleen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshComparative Studyen
dc.subject.meshDairy Productsen
dc.subject.meshDiabetes Mellitus, Type 1en
dc.subject.meshDiet Surveysen
dc.subject.meshFemaleen
dc.subject.meshHealth Surveysen
dc.subject.meshHumansen
dc.subject.meshIceland/epidemiologyen
dc.subject.meshIncidenceen
dc.subject.meshMaleen
dc.subject.meshResearch Support, Non-U.S. Gov'ten
dc.subject.meshScandinavia/epidemiologyen
dc.titleLower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinaviaen
dc.typeArticleen
dc.format.digYES-
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