2.50
Hdl Handle:
http://hdl.handle.net/2336/6486
Title:
Prevalence and risk factors for cornea guttata in the Reykjavik Eye Study
Authors:
Zoega, Gunnar M; Fujisawa, Aya; Sasaki, Hiroshi; Kubota, Akiko; Sasaki, Kazuyuki; Kitagawa, Kazuko; Jonasson, Fridbert
Citation:
Ophthalmology 2006, 113(4):565-9
Issue Date:
1-Apr-2006
Abstract:
PURPOSE: To establish the age- and gender-specific prevalence of cornea guttata (CG) in citizens of Reykjavik, Iceland, 55 years and older. DESIGN: Cross-sectional, random, population-based study. PARTICIPANTS: The 774 participants were those participating in the second examination of the Reykjavik Eye Study. At baseline, we had a response rate of 75.8%, and at the 5-year follow-up, 88% of the survivors participated. METHODS: We used slit-lamp and non-contact specular microscopy and endothelial specular photography as well as computer-assisted morphometry. We used a standardized grading system for CG. MAIN OUTCOME MEASURES: Diagnosis of primary central CG. RESULTS: The prevalence of CG is 11% for females and 7% for males both for right eyes and left eyes. Higher weight and higher body mass index are found to be associated with decreased risk of CG. Having smoked more than 20 pack-years increased the risk of CG more than 2-fold (P<0.02). CONCLUSIONS: Cornea guttata seem to be found more commonly in women than in men. Smoking for more than 20 pack-years increases the risk of developing CG more than 2-fold.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VT2-4JMM042-9&_user=2631555&_coverDate=04%2F30%2F2006&_alid=505748300&_rdoc=1&_fmt=full&_orig=search&_qd=1&_cdi=6278&_sort=d&_docanchor=&view=c&_acct=C000058274&_version=1&_urlVersion=0&_userid=2631555&md5=30c6ca31d7a5defe4012b835b4788a41

Full metadata record

DC FieldValue Language
dc.contributor.authorZoega, Gunnar M-
dc.contributor.authorFujisawa, Aya-
dc.contributor.authorSasaki, Hiroshi-
dc.contributor.authorKubota, Akiko-
dc.contributor.authorSasaki, Kazuyuki-
dc.contributor.authorKitagawa, Kazuko-
dc.contributor.authorJonasson, Fridbert-
dc.date.accessioned2006-12-11T14:09:29Z-
dc.date.available2006-12-11T14:09:29Z-
dc.date.issued2006-04-01-
dc.date.submitted2006-12-11-
dc.identifier.citationOphthalmology 2006, 113(4):565-9en
dc.identifier.issn1549-4713-
dc.identifier.pmid16581419-
dc.identifier.doi10.1016/j.ophtha.2005.12.014-
dc.identifier.otherOPH12-
dc.identifier.urihttp://hdl.handle.net/2336/6486-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractPURPOSE: To establish the age- and gender-specific prevalence of cornea guttata (CG) in citizens of Reykjavik, Iceland, 55 years and older. DESIGN: Cross-sectional, random, population-based study. PARTICIPANTS: The 774 participants were those participating in the second examination of the Reykjavik Eye Study. At baseline, we had a response rate of 75.8%, and at the 5-year follow-up, 88% of the survivors participated. METHODS: We used slit-lamp and non-contact specular microscopy and endothelial specular photography as well as computer-assisted morphometry. We used a standardized grading system for CG. MAIN OUTCOME MEASURES: Diagnosis of primary central CG. RESULTS: The prevalence of CG is 11% for females and 7% for males both for right eyes and left eyes. Higher weight and higher body mass index are found to be associated with decreased risk of CG. Having smoked more than 20 pack-years increased the risk of CG more than 2-fold (P<0.02). CONCLUSIONS: Cornea guttata seem to be found more commonly in women than in men. Smoking for more than 20 pack-years increases the risk of developing CG more than 2-fold.en
dc.language.isoenen
dc.relation.urlhttp://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VT2-4JMM042-9&_user=2631555&_coverDate=04%2F30%2F2006&_alid=505748300&_rdoc=1&_fmt=full&_orig=search&_qd=1&_cdi=6278&_sort=d&_docanchor=&view=c&_acct=C000058274&_version=1&_urlVersion=0&_userid=2631555&md5=30c6ca31d7a5defe4012b835b4788a41en
dc.subject.meshAge Distributionen
dc.subject.meshAgeden
dc.subject.meshAged, 80 and overen
dc.subject.meshCell Counten
dc.subject.meshCorneal Diseasesen
dc.subject.meshCross-Sectional Studiesen
dc.subject.meshDescemet Membraneen
dc.subject.meshEndothelium, Cornealen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshIceland/epidemiologyen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshPrevalenceen
dc.subject.meshResearch Support, Non-U.S. Gov'ten
dc.subject.meshRisk Factorsen
dc.subject.meshSex Distributionen
dc.titlePrevalence and risk factors for cornea guttata in the Reykjavik Eye Studyen
dc.typeArticleen
dc.identifier.journalOphthalmologyen
dc.format.digYES-

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