2.50
Hdl Handle:
http://hdl.handle.net/2336/6563
Title:
Ibutilide for treatment of atrial fibrillation in the emergency department
Authors:
Viktorsdottir, O; Henriksdottir, A; Arnar, D O
Citation:
Emerg Med J 2006, 23(2):133-4
Issue Date:
1-Feb-2006
Abstract:
The purpose of this study was to assess the efficacy and safety of ibutilide, a class III antiarrhythmic drug, for acute treatment of atrial fibrillation (AF) in the emergency department (ED) setting. A retrospective analysis was done reviewing all patients with AF who received ibutilide in the ED in a university hospital setting. A total of 22 patients received ibutilide. Another 24 patients who received rate control drugs only served as a control group. Of the 22 patients who received ibutilide, 14 (64%) converted to sinus rhythm. The mean (SD) rate of AF was 137 (24) bpm and the mean QTc interval immediately after conversion to sinus rhythm was 420 (28) ms. There were no complications. In the rate control group 7 patients (29%) converted to sinus rhythm (p<0.05, compared with ibutilide). The mean rate of AF was 126 (26) bpm (p = ns, compared with ibutilide) and the mean QTc interval in those who converted was 377 (28) ms (p<0.05, compared with ibutilide). One patient developed severe bradycardia. Ibutilide is effective for conversion of recent onset AF in patients presenting to the ED and there is a low rate of complications from ibutilide in this setting.
Description:
To access publisher version of this article. Please click on the hyperlink in Additional Links Field; To access full text version of this article. Please click on the hyperlink "View/Open" at the bottom of this page
Additional Links:
http://emj.bmj.com/cgi/content/full/23/2/133

Full metadata record

DC FieldValue Language
dc.contributor.authorViktorsdottir, O-
dc.contributor.authorHenriksdottir, A-
dc.contributor.authorArnar, D O-
dc.date.accessioned2006-12-14T13:02:11Z-
dc.date.available2006-12-14T13:02:11Z-
dc.date.issued2006-02-01-
dc.date.submitted2006-12-14-
dc.identifier.citationEmerg Med J 2006, 23(2):133-4en
dc.identifier.issn1472-0213-
dc.identifier.pmid16439743-
dc.identifier.doi10.1136/emj.2004.021394-
dc.identifier.otherEAM12-
dc.identifier.urihttp://hdl.handle.net/2336/6563-
dc.descriptionTo access publisher version of this article. Please click on the hyperlink in Additional Links Fielden
dc.descriptionTo access full text version of this article. Please click on the hyperlink "View/Open" at the bottom of this pageen
dc.description.abstractThe purpose of this study was to assess the efficacy and safety of ibutilide, a class III antiarrhythmic drug, for acute treatment of atrial fibrillation (AF) in the emergency department (ED) setting. A retrospective analysis was done reviewing all patients with AF who received ibutilide in the ED in a university hospital setting. A total of 22 patients received ibutilide. Another 24 patients who received rate control drugs only served as a control group. Of the 22 patients who received ibutilide, 14 (64%) converted to sinus rhythm. The mean (SD) rate of AF was 137 (24) bpm and the mean QTc interval immediately after conversion to sinus rhythm was 420 (28) ms. There were no complications. In the rate control group 7 patients (29%) converted to sinus rhythm (p<0.05, compared with ibutilide). The mean rate of AF was 126 (26) bpm (p = ns, compared with ibutilide) and the mean QTc interval in those who converted was 377 (28) ms (p<0.05, compared with ibutilide). One patient developed severe bradycardia. Ibutilide is effective for conversion of recent onset AF in patients presenting to the ED and there is a low rate of complications from ibutilide in this setting.en
dc.language.isoenen
dc.publisherBMJ Pub. Groupen
dc.relation.urlhttp://emj.bmj.com/cgi/content/full/23/2/133en
dc.subject.meshAnti-Arrhythmia Agentsen
dc.subject.meshAtrial Fibrillationen
dc.subject.meshCase-Control Studiesen
dc.subject.meshEmergency Service, Hospitalen
dc.subject.meshFemaleen
dc.subject.meshMaleen
dc.subject.meshHumansen
dc.subject.meshMiddle Ageden
dc.subject.meshRetrospective Studiesen
dc.subject.meshSulfonamidesen
dc.titleIbutilide for treatment of atrial fibrillation in the emergency departmenten
dc.typeArticleen
dc.identifier.journalEmergency medicine journalen
dc.format.digYES-

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