Algengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkenni

2.50
Hdl Handle:
http://hdl.handle.net/2336/6604
Title:
Algengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkenni
Other Titles:
Foodborne infections in Iceland. Relationship to allergy and lung function
Authors:
Hulda Ásbjörnsdóttir; Rúna B Sigurjónsdóttir; Signý V Sveinsdóttir; Alda Birgisdóttir; Davíð Gíslason; Christer Jansson; Ísleifur Ólafsson; Þórarinn Gíslason; Bjarni Þjóðleifsson
Citation:
Læknablaðið 2006, 92(6):437-44
Issue Date:
1-Jun-2006
Abstract:
BACKGROUND: Foodborne or orofecal transmitted infections can have influence on health by direct consequences of the infection and indirectly by modulating the immune system. OBJECTIVES: To investigate the prevalence and risk factors for T. gondii, H. pylori and HAV infection in the Icelandic population and their influence on atopy, allergy related lung symptoms and lung function. MATERIAL AND METHODS: Blood samples were collected in 1999-2001 from 505 subjects in age group 28-52, randomly selected from the Icelandic population. The presence of T. gondii, H. pylori and HAV IgG antibodies was determined by an ELISA method. Allergy related lung symptoms were assessed with questionnaire and IgE sensitization and lung function measured. X(2) test was used to test for trend but unadjusted logistic regression for comparison of IgG prevalence. Multiple logistic regression was used to calculate adjusted odds ratios and 95% confidence intervals for different infections factors. RESULTS: The prevalence of antibodies was 9.8%, for T. gondii, 36.3% for H. pylori and 4.9% for HAV. Attending day care before the age of 3 years was a risk factor for having T. gondii antibodies. The prevalence of H. pylori increased with age and smoking. The infections were not associated with the prevalence of asthma or atopy. Having IgG antibodies against T. gondii was, however, associated with an increased risk of having FEV/FVC ratio below 70%. CONCLUSION: T. gondii, H. pylori and H AV infection does not influence the prevalence of atopy or asthma. The data indicated that infection with T. gondii might be associated with a diminished lung function.
Description:
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open
Additional Links:
http://www.laeknabladid.is

Full metadata record

DC FieldValue Language
dc.contributor.authorHulda Ásbjörnsdóttir-
dc.contributor.authorRúna B Sigurjónsdóttir-
dc.contributor.authorSigný V Sveinsdóttir-
dc.contributor.authorAlda Birgisdóttir-
dc.contributor.authorDavíð Gíslason-
dc.contributor.authorChrister Jansson-
dc.contributor.authorÍsleifur Ólafsson-
dc.contributor.authorÞórarinn Gíslason-
dc.contributor.authorBjarni Þjóðleifsson-
dc.date.accessioned2006-12-18T12:17:02Z-
dc.date.available2006-12-18T12:17:02Z-
dc.date.issued2006-06-01-
dc.date.submitted2006-12-18-
dc.identifier.citationLæknablaðið 2006, 92(6):437-44en
dc.identifier.issn0023-7213-
dc.identifier.pmid16819003-
dc.identifier.otherPAD12-
dc.identifier.otherGAS12-
dc.identifier.urihttp://hdl.handle.net/2336/6604-
dc.descriptionNeðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Openen
dc.description.abstractBACKGROUND: Foodborne or orofecal transmitted infections can have influence on health by direct consequences of the infection and indirectly by modulating the immune system. OBJECTIVES: To investigate the prevalence and risk factors for T. gondii, H. pylori and HAV infection in the Icelandic population and their influence on atopy, allergy related lung symptoms and lung function. MATERIAL AND METHODS: Blood samples were collected in 1999-2001 from 505 subjects in age group 28-52, randomly selected from the Icelandic population. The presence of T. gondii, H. pylori and HAV IgG antibodies was determined by an ELISA method. Allergy related lung symptoms were assessed with questionnaire and IgE sensitization and lung function measured. X(2) test was used to test for trend but unadjusted logistic regression for comparison of IgG prevalence. Multiple logistic regression was used to calculate adjusted odds ratios and 95% confidence intervals for different infections factors. RESULTS: The prevalence of antibodies was 9.8%, for T. gondii, 36.3% for H. pylori and 4.9% for HAV. Attending day care before the age of 3 years was a risk factor for having T. gondii antibodies. The prevalence of H. pylori increased with age and smoking. The infections were not associated with the prevalence of asthma or atopy. Having IgG antibodies against T. gondii was, however, associated with an increased risk of having FEV/FVC ratio below 70%. CONCLUSION: T. gondii, H. pylori and H AV infection does not influence the prevalence of atopy or asthma. The data indicated that infection with T. gondii might be associated with a diminished lung function.en
dc.languageiceen
dc.language.isoisen
dc.publisherLæknafélag Íslands, Læknafélag Reykjavíkuren
dc.relation.urlhttp://www.laeknabladid.isen
dc.subjectFaraldsfræðiis
dc.subjectSmitsjúkdómaris
dc.subjectLungnasjúkdómaris
dc.subjectOfnæmien
dc.subjectVeiruren
dc.subject.classificationFræðigreinaren
dc.subject.classificationLBL12en
dc.subject.meshAdulten
dc.subject.meshAnimalsen
dc.subject.meshAntibodies, Bacterialen
dc.subject.meshAntibodies, Protozoanen
dc.subject.meshAsthmaen
dc.subject.meshEnglish Abstracten
dc.subject.meshEnzyme-Linked Immunosorbent Assayen
dc.subject.meshFemaleen
dc.subject.meshFood Poisoningen
dc.subject.meshForced Expiratory Volumeen
dc.subject.meshHelicobacter Infectionsen
dc.subject.meshHelicobacter pylorien
dc.subject.meshHepatitis Aen
dc.subject.meshHepatitis A virusen
dc.subject.meshHumansen
dc.subject.meshHypersensitivity, Immediateen
dc.subject.meshIceland/epidemiologyen
dc.subject.meshImmunoglobulin Gen
dc.subject.meshLogistic Modelsen
dc.subject.meshLungen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshOdds Ratioen
dc.subject.meshPrevalenceen
dc.subject.meshQuestionnairesen
dc.subject.meshToxoplasmaen
dc.titleAlgengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkennien
dc.title.alternativeFoodborne infections in Iceland. Relationship to allergy and lung functionen
dc.typeArticleen
dc.identifier.journalLæknablaðiðis
dc.format.digYES-

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