2.50
Hdl Handle:
http://hdl.handle.net/2336/74395
Title:
Acute epiglottitis in Iceland 1983-2005
Authors:
Briem, Birgir; Thorvardsson, Ornolfur; Petersen, Hannes
Citation:
Auris Nasus Larynx. 2009, 36(1):46-52
Issue Date:
1-Feb-2009
Abstract:
OBJECTIVE: To describe the changes in the epidemiology of epiglottitis in Iceland from 1983 to 2005. METHODS: All patients with the discharge diagnosis of epiglottitis during the study years were identified and diagnosis confirmed by chart review. Main outcome measures were age, gender, month/year of diagnosis, microbiology, airway management, ICU admissions, choice of antibiotics, length of hospital stay and major complications/mortality. RESULTS: Fifty-seven patients were identified (annual incidence 0.93/100.000). The mean age was 33.3 years (1-82). Childhood epiglottitis disappeared after introduction of Haemophilus influenzae type b (Hib) vaccination in 1989 but adult disease showed non-significant increase. In the pre-vaccination era Hib was the most common organism cultured but it has not been diagnosed in Iceland since 1991 and Streptococci are now the leading cause of epiglottitis. The mean hospital stay was 5.05 nights with 51% of patients admitted to ICU. All children under 10 years and a total 30% of patients received airway intervention. Ninety percent of adults were observed without airway intervention. Major complications were rare and mortality was 0% in our series. CONCLUSION: There have been major changes in the epidemiology of epiglottitis in Iceland during the study period. Previously a childhood disease, epiglottitis has disappeared in children and is now almost exclusively found in adults. This can be attributed to widespread Hib vaccination, eliminating the major causative agent in children. The treatment of this life-threatening disease remains a challenge. Our series suggest that it is safe to observe patients with mild/moderate symptoms without airway intervention.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www.sciencedirect.com/science/article/B6T4M-4SK59DK-1/2/83a4d44f7debb0d782353d67504e4073

Full metadata record

DC FieldValue Language
dc.contributor.authorBriem, Birgir-
dc.contributor.authorThorvardsson, Ornolfur-
dc.contributor.authorPetersen, Hannes-
dc.date.accessioned2009-07-17T15:42:32Z-
dc.date.available2009-07-17T15:42:32Z-
dc.date.issued2009-02-01-
dc.date.submitted2009-07-17-
dc.identifier.citationAuris Nasus Larynx. 2009, 36(1):46-52en
dc.identifier.issn1879-1476-
dc.identifier.pmid18502071-
dc.identifier.doi10.1016/j.anl.2008.03.012-
dc.identifier.urihttp://hdl.handle.net/2336/74395-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractOBJECTIVE: To describe the changes in the epidemiology of epiglottitis in Iceland from 1983 to 2005. METHODS: All patients with the discharge diagnosis of epiglottitis during the study years were identified and diagnosis confirmed by chart review. Main outcome measures were age, gender, month/year of diagnosis, microbiology, airway management, ICU admissions, choice of antibiotics, length of hospital stay and major complications/mortality. RESULTS: Fifty-seven patients were identified (annual incidence 0.93/100.000). The mean age was 33.3 years (1-82). Childhood epiglottitis disappeared after introduction of Haemophilus influenzae type b (Hib) vaccination in 1989 but adult disease showed non-significant increase. In the pre-vaccination era Hib was the most common organism cultured but it has not been diagnosed in Iceland since 1991 and Streptococci are now the leading cause of epiglottitis. The mean hospital stay was 5.05 nights with 51% of patients admitted to ICU. All children under 10 years and a total 30% of patients received airway intervention. Ninety percent of adults were observed without airway intervention. Major complications were rare and mortality was 0% in our series. CONCLUSION: There have been major changes in the epidemiology of epiglottitis in Iceland during the study period. Previously a childhood disease, epiglottitis has disappeared in children and is now almost exclusively found in adults. This can be attributed to widespread Hib vaccination, eliminating the major causative agent in children. The treatment of this life-threatening disease remains a challenge. Our series suggest that it is safe to observe patients with mild/moderate symptoms without airway intervention.en
dc.language.isoenen
dc.publisherElsevier Scienceen
dc.relation.urlhttp://www.sciencedirect.com/science/article/B6T4M-4SK59DK-1/2/83a4d44f7debb0d782353d67504e4073en
dc.subject.meshAcute Diseaseen
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshAge Distributionen
dc.subject.meshAgeden
dc.subject.meshAged, 80 and overen
dc.subject.meshAnti-Bacterial Agentsen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshEpiglottitisen
dc.subject.meshFemaleen
dc.subject.meshHaemophilus Vaccinesen
dc.subject.meshHaemophilus influenzae type ben
dc.subject.meshHumansen
dc.subject.meshIcelanden
dc.subject.meshIncidenceen
dc.subject.meshInfanten
dc.subject.meshIntensive Care Unitsen
dc.subject.meshIntubation, Intratrachealen
dc.subject.meshLength of Stayen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshRetrospective Studiesen
dc.subject.meshSeasonsen
dc.subject.meshSex Distributionen
dc.subject.meshStreptococcusen
dc.subject.meshTracheotomyen
dc.subject.meshYoung Adulten
dc.titleAcute epiglottitis in Iceland 1983-2005en
dc.typeArticleen
dc.contributor.departmentDepartment of Otolaryngology, Buskerud Central Hospital, Dronninggata 28, 3004 Drammen, Norway. birgir.briem@gmail.comen
dc.identifier.journalAuris, nasus, larynxen

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