Vitamin D deficiency and nutritional status in elderly hospitalized subjects in Iceland

2.50
Hdl Handle:
http://hdl.handle.net/2336/76319
Title:
Vitamin D deficiency and nutritional status in elderly hospitalized subjects in Iceland
Authors:
Ramel, Alfons; Jonsson, Palmi V; Bjornsson, Sigurbjorn; Thorsdottir, Inga
Citation:
Public Health Nutr. 2009, 12(7):1001-5
Issue Date:
1-Jul-2009
Abstract:
OBJECTIVE: Poor nutrition and limited sunlight exposure (season) can be related to reduced serum 25-hydroxyvitamin D (25(OH)D) concentrations. Thus, elderly people in the Nordic countries might be at high risk for vitamin D deficiency. The aims of the study were to describe the prevalence of vitamin D deficiency in elderly hospitalized patients in Reykjavik, Iceland, and to investigate the effects of nutritional status and season on serum 25(OH)D. DESIGN: Cross-sectional study. Nutritional status was assessed and fasting blood was drawn and analysed for serum 25(OH)D and other clinical routine measurements. SETTING: Departments of Geriatrics, Landspitali-University Hospital, Reykjavik, Iceland. SUBJECTS: Sixty hospitalized patients (mean age 83.0 (SD 7.9) years) were randomly assigned. RESULTS: Of the patients, 12.3% suffered from vitamin D deficiency (serum 25(OH)D < 25 nmol/l) and 71.9% suffered from hypovitaminosis D (serum 25(OH)D = 25-75 nmol/l). There were no significant effects of gender or nutritional status on serum 25(OH)D. Anthropometric variables correlated significantly with serum 25(OH)D, but on stepwise linear regression modelling for the prediction of serum 25(OH)D, BMI remained the only predictor variable (B = -1.454, 95% CI -2.535, -0.373, P = 0.009). CONCLUSIONS: BMI was significantly negatively associated with serum 25(OH)D in hospitalized elderly patients. Neither nutritional status nor season significantly affected serum 25(OH)D in our patient group. Higher levels of serum 25(OH)D in elderly subjects with lower BMI are most likely explained by volume of distribution rather than by mobilization of vitamin D from its storage in adipose tissue due to age and disease-related catabolism.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://dx.doi.org/10.1017/S1368980008004527

Full metadata record

DC FieldValue Language
dc.contributor.authorRamel, Alfons-
dc.contributor.authorJonsson, Palmi V-
dc.contributor.authorBjornsson, Sigurbjorn-
dc.contributor.authorThorsdottir, Inga-
dc.date.accessioned2009-08-05T09:37:09Z-
dc.date.available2009-08-05T09:37:09Z-
dc.date.issued2009-07-01-
dc.date.submitted2009-08-05-
dc.identifier.citationPublic Health Nutr. 2009, 12(7):1001-5en
dc.identifier.issn1475-2727-
dc.identifier.pmid19144240-
dc.identifier.doi10.1017/S1368980008004527-
dc.identifier.urihttp://hdl.handle.net/2336/76319-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractOBJECTIVE: Poor nutrition and limited sunlight exposure (season) can be related to reduced serum 25-hydroxyvitamin D (25(OH)D) concentrations. Thus, elderly people in the Nordic countries might be at high risk for vitamin D deficiency. The aims of the study were to describe the prevalence of vitamin D deficiency in elderly hospitalized patients in Reykjavik, Iceland, and to investigate the effects of nutritional status and season on serum 25(OH)D. DESIGN: Cross-sectional study. Nutritional status was assessed and fasting blood was drawn and analysed for serum 25(OH)D and other clinical routine measurements. SETTING: Departments of Geriatrics, Landspitali-University Hospital, Reykjavik, Iceland. SUBJECTS: Sixty hospitalized patients (mean age 83.0 (SD 7.9) years) were randomly assigned. RESULTS: Of the patients, 12.3% suffered from vitamin D deficiency (serum 25(OH)D < 25 nmol/l) and 71.9% suffered from hypovitaminosis D (serum 25(OH)D = 25-75 nmol/l). There were no significant effects of gender or nutritional status on serum 25(OH)D. Anthropometric variables correlated significantly with serum 25(OH)D, but on stepwise linear regression modelling for the prediction of serum 25(OH)D, BMI remained the only predictor variable (B = -1.454, 95% CI -2.535, -0.373, P = 0.009). CONCLUSIONS: BMI was significantly negatively associated with serum 25(OH)D in hospitalized elderly patients. Neither nutritional status nor season significantly affected serum 25(OH)D in our patient group. Higher levels of serum 25(OH)D in elderly subjects with lower BMI are most likely explained by volume of distribution rather than by mobilization of vitamin D from its storage in adipose tissue due to age and disease-related catabolism.en
dc.language.isoenen
dc.publisherPublished on behalf of the Nutrition Society by CAB Internationalen
dc.relation.urlhttp://dx.doi.org/10.1017/S1368980008004527en
dc.subject.meshAgeden
dc.subject.meshAged, 80 and overen
dc.subject.meshAgingen
dc.subject.meshBody Mass Indexen
dc.subject.meshCross-Sectional Studiesen
dc.subject.meshFemaleen
dc.subject.meshGeriatric Assessmenten
dc.subject.meshHospitalizationen
dc.subject.meshHumansen
dc.subject.meshIcelanden
dc.subject.meshLinear Modelsen
dc.subject.meshMaleen
dc.subject.meshNutrition Assessmenten
dc.subject.meshNutritional Statusen
dc.subject.meshRisk Factorsen
dc.subject.meshSeasonsen
dc.subject.meshSunlighten
dc.subject.meshVitamin Den
dc.subject.meshVitamin D Deficiencyen
dc.titleVitamin D deficiency and nutritional status in elderly hospitalized subjects in Icelanden
dc.typeArticleen
dc.contributor.departmentUnit for Nutrition Research, Landspitali-University Hospital and Department of Food Science and Human Nutrition, University of Iceland, Eiriksgata 29, 101 Reykjavik, Iceland. alfons@landspitali.isen
dc.identifier.journalPublic health nutritionen

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