2.50
Hdl Handle:
http://hdl.handle.net/2336/80374
Title:
COMT val(158)met genotype and smooth pursuit eye movements in schizophrenia
Authors:
Haraldsson, H M; Ettinger, U; Magnusdottir, B B; Sigmundsson, T; Sigurdsson, E; Ingason, A; Petursson, H
Citation:
Psychiatry Res. 2009, 169(2):173-175
Issue Date:
30-Sep-2009
Abstract:
The association between the catechol-O-methyltransferase (COMT) val(158)met polymorphism (rs4680) and smooth pursuit eye movements (SPEM) was investigated in 110 schizophrenia patients and 96 controls. Patients had lower steady-state pursuit gain and made more frequent saccades than controls. Genotype was not associated with schizophrenia or SPEM, in either group or the combined sample. SPEM deficits in schizophrenia appear to be determined by genotypes other than rs4680, although the study may have lacked power to detect small effects.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://dx.doi.org/10.1016/j.psychres.2008.10.003

Full metadata record

DC FieldValue Language
dc.contributor.authorHaraldsson, H M-
dc.contributor.authorEttinger, U-
dc.contributor.authorMagnusdottir, B B-
dc.contributor.authorSigmundsson, T-
dc.contributor.authorSigurdsson, E-
dc.contributor.authorIngason, A-
dc.contributor.authorPetursson, H-
dc.date.accessioned2009-09-08T14:34:49Z-
dc.date.available2009-09-08T14:34:49Z-
dc.date.issued2009-09-30-
dc.date.submitted2009-09-08-
dc.identifier.citationPsychiatry Res. 2009, 169(2):173-175en
dc.identifier.issn0165-1781-
dc.identifier.pmid19647329-
dc.identifier.doi10.1016/j.psychres.2008.10.003-
dc.identifier.urihttp://hdl.handle.net/2336/80374-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractThe association between the catechol-O-methyltransferase (COMT) val(158)met polymorphism (rs4680) and smooth pursuit eye movements (SPEM) was investigated in 110 schizophrenia patients and 96 controls. Patients had lower steady-state pursuit gain and made more frequent saccades than controls. Genotype was not associated with schizophrenia or SPEM, in either group or the combined sample. SPEM deficits in schizophrenia appear to be determined by genotypes other than rs4680, although the study may have lacked power to detect small effects.en
dc.languageENG-
dc.language.ison/aen
dc.publisherElsevier/North-Holland Biomedical Pressen
dc.relation.urlhttp://dx.doi.org/10.1016/j.psychres.2008.10.003en
dc.titleCOMT val(158)met genotype and smooth pursuit eye movements in schizophrenian/a
dc.typeArticleen
dc.contributor.departmentDivision of Psychiatry, Landspitali-University Hospital, Reykjavik, Iceland.en
dc.identifier.journalPsychiatry researchen

Related articles on PubMed

All Items in Hirsla are protected by copyright, with all rights reserved, unless otherwise indicated.