2.50
Hdl Handle:
http://hdl.handle.net/2336/85233
Title:
64,XX, SRY-, and ZFY-negative Icelandic horse likely to be true hermaphrodite
Authors:
Bodvarsdottir, S K; Imsland, F; Thorisson, B; Steinarsdottir, M; Eyfjord, J E
Citation:
J. Equine Vet. Sci. 2009, 29(10):734-8
Issue Date:
1-Oct-2009
Abstract:
A 4-year-old Icelandic horse, considered to be a mare, showed stallion-like behavior in a group of mares. On clinical examination, the horse turned out to have an enlarged erectable phallic clitoris. Ultrasound examination showed a normal-sized left ovary covered with numerous small follicular cysts and a compact testis-like tissue in place of the right ovary. The karyotype was normal for a mare (64,XX), and the horse was found to be negative for the Y chromosome-specific markers SRY, ZFY, and EIF1AY. This case indicates that the intersexual phenotype may be caused by autosomal recessive mutation, resulting in defects in cortisol biosynthesis rather than transferal of Y chromosome male-specific genes. This is the first report of an intersexual phenotype in an Icelandic horse that is likely to be a true hermaphrodite because of female sex chromosomes and a mixture of female and male gonads and external genitals.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://dx.doi.org/10.1016/j.jevs.2009.08.007

Full metadata record

DC FieldValue Language
dc.contributor.authorBodvarsdottir, S Ken
dc.contributor.authorImsland, Fen
dc.contributor.authorThorisson, Ben
dc.contributor.authorSteinarsdottir, Men
dc.contributor.authorEyfjord, J Een
dc.date.accessioned2009-11-03T09:40:51Z-
dc.date.available2009-11-03T09:40:51Z-
dc.date.issued2009-10-01-
dc.date.submitted2009-11-03-
dc.identifier.citationJ. Equine Vet. Sci. 2009, 29(10):734-8en
dc.identifier.issn07370806-
dc.identifier.doi10.1016/j.jevs.2009.08.007-
dc.identifier.urihttp://hdl.handle.net/2336/85233-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractA 4-year-old Icelandic horse, considered to be a mare, showed stallion-like behavior in a group of mares. On clinical examination, the horse turned out to have an enlarged erectable phallic clitoris. Ultrasound examination showed a normal-sized left ovary covered with numerous small follicular cysts and a compact testis-like tissue in place of the right ovary. The karyotype was normal for a mare (64,XX), and the horse was found to be negative for the Y chromosome-specific markers SRY, ZFY, and EIF1AY. This case indicates that the intersexual phenotype may be caused by autosomal recessive mutation, resulting in defects in cortisol biosynthesis rather than transferal of Y chromosome male-specific genes. This is the first report of an intersexual phenotype in an Icelandic horse that is likely to be a true hermaphrodite because of female sex chromosomes and a mixture of female and male gonads and external genitals.en
dc.language.isoisen
dc.publisherW. B. Saunders Co.en
dc.relation.urlhttp://dx.doi.org/10.1016/j.jevs.2009.08.007en
dc.title64,XX, SRY-, and ZFY-negative Icelandic horse likely to be true hermaphroditeis
dc.typeArticleen
dc.identifier.journalJournal of equine veterinary scienceen
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