2.50
Hdl Handle:
http://hdl.handle.net/2336/93523
Title:
Tolerance of intravenously administered ciprofloxacin
Authors:
Thorsteinsson, S B; Bergan, T; Rohwedder, R
Citation:
Chemotherapy 1988, 34(3):256-60
Issue Date:
1988
Abstract:
Twelve healthy volunteers received single doses of 200, 300, and 400 mg ciprofloxacin intravenously (30-min infusion). Crystals appeared in the urine of only 1 subject after the 400 mg dose. The crystals appeared in the 0-2 h urine specimen only and were observed immediately upon voiding while the urine was maintained at 37 degrees C. The pH of the urine was 7.3. The event was without untoward consequences to the person as evidenced by urinalysis and blood chemistry. Local skin reactions occurred on the arm of the infusion (cutaneous erythema, itching and burning sensation). The reactions were less after the lowest dose. The reactions started within minutes after the beginning of the infusion and disappeared either during the infusions or immediately after the end of administration. These local reactions were of moderate degree and did not necessitate termination of the infusion.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://dx.doi.org/10.1159/000238577

Full metadata record

DC FieldValue Language
dc.contributor.authorThorsteinsson, S Ben
dc.contributor.authorBergan, Ten
dc.contributor.authorRohwedder, Ren
dc.date.accessioned2010-03-03T13:03:05Z-
dc.date.available2010-03-03T13:03:05Z-
dc.date.issued1988-
dc.date.submitted2010-03-03-
dc.identifier.citationChemotherapy 1988, 34(3):256-60en
dc.identifier.issn0009-3157-
dc.identifier.pmid3416662-
dc.identifier.doi10.1159/000238577-
dc.identifier.urihttp://hdl.handle.net/2336/93523-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractTwelve healthy volunteers received single doses of 200, 300, and 400 mg ciprofloxacin intravenously (30-min infusion). Crystals appeared in the urine of only 1 subject after the 400 mg dose. The crystals appeared in the 0-2 h urine specimen only and were observed immediately upon voiding while the urine was maintained at 37 degrees C. The pH of the urine was 7.3. The event was without untoward consequences to the person as evidenced by urinalysis and blood chemistry. Local skin reactions occurred on the arm of the infusion (cutaneous erythema, itching and burning sensation). The reactions were less after the lowest dose. The reactions started within minutes after the beginning of the infusion and disappeared either during the infusions or immediately after the end of administration. These local reactions were of moderate degree and did not necessitate termination of the infusion.en
dc.language.isoenen
dc.publisherKargeren
dc.relation.urlhttp://dx.doi.org/10.1159/000238577en
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshCiprofloxacinen
dc.subject.meshCrystallizationen
dc.subject.meshErythemaen
dc.subject.meshHumansen
dc.subject.meshHydrogen-Ion Concentrationen
dc.subject.meshInfusions, Intravenousen
dc.subject.meshTime Factorsen
dc.subject.meshUrineen
dc.titleTolerance of intravenously administered ciprofloxacinen
dc.typeArticleen
dc.contributor.departmentDepartment of Internal Medicine, University Hospital, Reykjavik, Iceland.en
dc.identifier.journalChemotherapyen

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