2.50
Hdl Handle:
http://hdl.handle.net/2336/93563
Title:
Additive effects of moderate dietary salt reduction and captopril in hypertension
Authors:
Kristinsson, A; Hardarson, T; Palsson, K; Petursson, M K; Snorrason, S P; Thorgeirsson, G
Citation:
Acta Med Scand. 1988, 223(2):133-7
Issue Date:
1988
Abstract:
In a randomized, cross-over study 27 patients had diastolic blood pressure of greater than or equal to 96 mmHg during four visits without treatment. Following captopril 25 mg b.i.d. nine patients' blood pressure was less than or equal to 90 mmHg. The remaining 18 were randomized into two treatment modalities, captopril and moderate dietary salt reduction, and captopril and hydrochlorothiazide 25 mg daily. Following a wash-out period the groups crossed over to the alternative treatment. At the end of the control period the average blood pressure was 151/100 +/- 12/6 mmHg recumbent and 140/91 +/- 11/7 standing, following captopril 144/94 +/- 13/5 and 132/92 +/- 12/6, respectively, with low salt diet added to captopril 140/91 +/- 12/6 and 128/89 +/- 11/6 and with hydrochlorothiazide and captopril 133/86 +/- 12/7 and 120/84 +/- 11/7 mmHg supine and erect, respectively. It is concluded that moderate dietary salt reduction, which is easily advised, will significantly potentiate the blood pressure fall following captopril treatment in moderate arterial hypertension.
Description:
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Additional Links:
http://www3.interscience.wiley.com/journal/122315107/abstract

Full metadata record

DC FieldValue Language
dc.contributor.authorKristinsson, Aen
dc.contributor.authorHardarson, Ten
dc.contributor.authorPalsson, Ken
dc.contributor.authorPetursson, M Ken
dc.contributor.authorSnorrason, S Pen
dc.contributor.authorThorgeirsson, Gen
dc.date.accessioned2010-03-03T15:11:54Z-
dc.date.available2010-03-03T15:11:54Z-
dc.date.issued1988-
dc.date.submitted2010-
dc.identifier.citationActa Med Scand. 1988, 223(2):133-7en
dc.identifier.issn0001-6101-
dc.identifier.pmid3279725-
dc.identifier.doi10.1111/j.0954-6820.1988.tb15777.x-
dc.identifier.urihttp://hdl.handle.net/2336/93563-
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractIn a randomized, cross-over study 27 patients had diastolic blood pressure of greater than or equal to 96 mmHg during four visits without treatment. Following captopril 25 mg b.i.d. nine patients' blood pressure was less than or equal to 90 mmHg. The remaining 18 were randomized into two treatment modalities, captopril and moderate dietary salt reduction, and captopril and hydrochlorothiazide 25 mg daily. Following a wash-out period the groups crossed over to the alternative treatment. At the end of the control period the average blood pressure was 151/100 +/- 12/6 mmHg recumbent and 140/91 +/- 11/7 standing, following captopril 144/94 +/- 13/5 and 132/92 +/- 12/6, respectively, with low salt diet added to captopril 140/91 +/- 12/6 and 128/89 +/- 11/6 and with hydrochlorothiazide and captopril 133/86 +/- 12/7 and 120/84 +/- 11/7 mmHg supine and erect, respectively. It is concluded that moderate dietary salt reduction, which is easily advised, will significantly potentiate the blood pressure fall following captopril treatment in moderate arterial hypertension.en
dc.language.isoenen
dc.publisherDistributed by Almqvist and Wiksellen
dc.relation.urlhttp://www3.interscience.wiley.com/journal/122315107/abstracten
dc.subject.meshAdulten
dc.subject.meshAgeden
dc.subject.meshCaptoprilen
dc.subject.meshClinical Trials as Topicen
dc.subject.meshDiet, Sodium-Restricteden
dc.subject.meshDrug Therapy, Combinationen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshHydrochlorothiazideen
dc.subject.meshHypertensionen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshRandom Allocationen
dc.titleAdditive effects of moderate dietary salt reduction and captopril in hypertensionen
dc.typeArticleen
dc.contributor.departmentDepartment of Internal Medicine, Landspitalinn-University Hospital, Reykjavik, Iceland.en
dc.identifier.journalActa medica Scandinavicaen

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