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dc.contributor.authorZoëga, Helga
dc.contributor.authorBaldursson, Gisli
dc.contributor.authorHrafnkelsson, Birgir
dc.contributor.authorAlmarsdottir, Anna Birna
dc.contributor.authorValdimarsdottir, Unnur
dc.contributor.authorHalldorsson, Matthias
dc.date.accessioned2010-07-22T10:03:26Z
dc.date.available2010-07-22T10:03:26Z
dc.date.issued2009-12-26
dc.date.submitted2010-07-22
dc.identifier.citationJ Child Adolesc Psychopharmacol. 2009, 19(6):757-64en
dc.identifier.issn1557-8992
dc.identifier.pmid20035594
dc.identifier.doi10.1089/cap.2009.0003
dc.identifier.urihttp://hdl.handle.net/2336/108149
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractOBJECTIVE: The aim of this study was to investigate psychotropic drug use among children in Iceland between 2003 and 2007. METHODS: A nationwide population-based drug use study covering the total pediatric population (ages 0-17) in Iceland. Information was obtained from the National Medicines Registry to calculate prevalence of use by year and psychotropic drug group; incidence by year, psychotropic drug group, child's age and sex, and medical specialty of prescriber; the most commonly used psychotropic chemical substances, off-label and unlicensed use and concomitant psychotropic drug use. RESULTS: The overall prevalence of psychotropic drug use was 48.7 per 1000 Icelandic children in 2007. Stimulants and antidepressants increased in prevalence from 2003 to 2007 and were the two most prevalent psychotropic drug groups, respectively, 28.4 and 23.4 per 1000 children in 2007. A statistically significant trend of declining prevalence (p = 0.00013) and incidence (p = 0.0018) of antidepressant use occurred during the study period. Out of 21,986 psychotropic drugs dispensed in 2007, 25.4% were used off-label. CONCLUSIONS: With reference to reports from other European countries, the results indicate extensive psychotropic drug use among children in Iceland between 2003 and 2007. Further scrutiny is needed to assess the rationale behind this widespread use.
dc.language.isoenen
dc.publisherMary Ann Lieberten
dc.relation.urlhttp://dx.doi.org/10.1089/cap.2009.0003en
dc.subject.meshAdolescenten
dc.subject.meshAge Factorsen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshIcelanden
dc.subject.meshIncidenceen
dc.subject.meshInfanten
dc.subject.meshInfant, Newbornen
dc.subject.meshMaleen
dc.subject.meshMedicineen
dc.subject.meshMental Disordersen
dc.subject.meshOff-Label Useen
dc.subject.meshPhysician's Practice Patternsen
dc.subject.meshPopulation Surveillanceen
dc.subject.meshPrevalenceen
dc.subject.meshPsychotropic Drugsen
dc.subject.meshSex Factorsen
dc.titlePsychotropic drug use among Icelandic children: a nationwide population-based studyen
dc.typeArticleen
dc.contributor.departmentCentre of Public Health Sciences, University of Iceland, Reykjavík, Iceland. hez2@hi.isen
dc.identifier.journalJournal of child and adolescent psychopharmacologyen
html.description.abstractOBJECTIVE: The aim of this study was to investigate psychotropic drug use among children in Iceland between 2003 and 2007. METHODS: A nationwide population-based drug use study covering the total pediatric population (ages 0-17) in Iceland. Information was obtained from the National Medicines Registry to calculate prevalence of use by year and psychotropic drug group; incidence by year, psychotropic drug group, child's age and sex, and medical specialty of prescriber; the most commonly used psychotropic chemical substances, off-label and unlicensed use and concomitant psychotropic drug use. RESULTS: The overall prevalence of psychotropic drug use was 48.7 per 1000 Icelandic children in 2007. Stimulants and antidepressants increased in prevalence from 2003 to 2007 and were the two most prevalent psychotropic drug groups, respectively, 28.4 and 23.4 per 1000 children in 2007. A statistically significant trend of declining prevalence (p = 0.00013) and incidence (p = 0.0018) of antidepressant use occurred during the study period. Out of 21,986 psychotropic drugs dispensed in 2007, 25.4% were used off-label. CONCLUSIONS: With reference to reports from other European countries, the results indicate extensive psychotropic drug use among children in Iceland between 2003 and 2007. Further scrutiny is needed to assess the rationale behind this widespread use.


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