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dc.contributor.authorSigurdardottir, L Y
dc.contributor.authorHelgason, H
dc.date.accessioned2010-09-21T15:57:01Z
dc.date.available2010-09-21T15:57:01Z
dc.date.issued1997-03
dc.date.submitted2010-09-21
dc.identifier.citationPediatr Cardiol. 1997, 18(2):96-100en
dc.identifier.issn0172-0643
dc.identifier.pmid9049120
dc.identifier.doi10.1007/s002469900124
dc.identifier.urihttp://hdl.handle.net/2336/111580
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractPostoperative coarctation (CoA) patients are often found to have signs of persistent myocardial dysfunction. M-mode echocardiography was performed to study left ventricular (LV) size, mass, and systolic function and Doppler ultrasonography to study LV filling and flow velocity in the LV outflow tract and aorta in 28 "healthy" postoperative CoA patients (5-21 years) and 28 age- and sex-matched controls. The early (E) and late (A) diastolic transmitral velocities were significantly higher in the patient group than in the controls (p < 0.05). Other diastolic parameters (isovolumic relaxation time, E/A ratio, and deceleration time of the early diastolic velocity) were similar in the two groups (p = NS). The left atrial diameter, LV wall average, end-diastolic diameter of the LV and LV mass were higher in the patients than controls (p < 0.05). The patients also had a higher stroke volume, cardiac output, and cardiac index than the controls (p < 0.01). The fractional shortening was similar in the two groups (p = NS). Blood flow velocities in both the LV outflow tract and aorta were higher in the patients than the controls (p < 0.0002). We found LV hypertrophy with signs of a hyperdynamic circulation (increased cardiac index and stroke volume) in our patients. An increase in A is associated with LV hypertrophy and seems to be a sensitive marker of diastolic abnormality. The rise in E is paradoxical but has been seen in other studies. The increased blood flow velocity in the LV outflow tract suggests obstruction to LV outflow and increased flow in the descending aorta is due to residual coarctation.
dc.language.isoenen
dc.publisherSpringer Verlagen
dc.relation.urlhttp://dx.doi.org/10.1007/s002469900124en
dc.subject.meshAdolescenten
dc.subject.meshAortic Coarctationen
dc.subject.meshDiastoleen
dc.subject.meshExercise Testen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshHypertensionen
dc.subject.meshMaleen
dc.subject.meshSystoleen
dc.titleEchocardiographic evaluation of systolic and diastolic function in postoperative coarctation patientsen
dc.typeArticleen
dc.contributor.departmentUniversity of Iceland, Medical School, Reykjavik, Iceland.en
dc.identifier.journalPediatric cardiologyen
html.description.abstractPostoperative coarctation (CoA) patients are often found to have signs of persistent myocardial dysfunction. M-mode echocardiography was performed to study left ventricular (LV) size, mass, and systolic function and Doppler ultrasonography to study LV filling and flow velocity in the LV outflow tract and aorta in 28 "healthy" postoperative CoA patients (5-21 years) and 28 age- and sex-matched controls. The early (E) and late (A) diastolic transmitral velocities were significantly higher in the patient group than in the controls (p < 0.05). Other diastolic parameters (isovolumic relaxation time, E/A ratio, and deceleration time of the early diastolic velocity) were similar in the two groups (p = NS). The left atrial diameter, LV wall average, end-diastolic diameter of the LV and LV mass were higher in the patients than controls (p < 0.05). The patients also had a higher stroke volume, cardiac output, and cardiac index than the controls (p < 0.01). The fractional shortening was similar in the two groups (p = NS). Blood flow velocities in both the LV outflow tract and aorta were higher in the patients than the controls (p < 0.0002). We found LV hypertrophy with signs of a hyperdynamic circulation (increased cardiac index and stroke volume) in our patients. An increase in A is associated with LV hypertrophy and seems to be a sensitive marker of diastolic abnormality. The rise in E is paradoxical but has been seen in other studies. The increased blood flow velocity in the LV outflow tract suggests obstruction to LV outflow and increased flow in the descending aorta is due to residual coarctation.


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