• Epidemiology of penicillin-non-susceptible pneumococci in Iceland, 1995-2010.

      Hjálmarsdóttir, M Á; Kristinsson, K G; a Department of Clinical Microbiology, Landspitali University Hospital, Baronsstig, 101 Reykjavik, Iceland b University of Iceland, Stapi v/Hringbraut, 101 Reykjavik, Iceland (Oxford University Press, 2014-04)
      The first penicillin-non-susceptible pneumococci (PNSP) were identified in Iceland in 1988. A rapid increase followed, associated with expansion of a single multiresistant clone, Spain(6B)-2, peaking at 19.8% in 1993. After interventions led to reduced antimicrobial use in children, the prevalence of PNSP decreased until 1995. The aim of this study was to follow the evolution of PNSP from 1995 to 2010, the period preceding the introduction of conjugated pneumococcal vaccines into the vaccination programme.
    • Prevalence of pilus genes in pneumococci isolated from healthy preschool children in Iceland: association with vaccine serotypes and antibiotic resistance.

      Hjálmarsdóttir, Martha Á; Pétursdóttir, Brynhildur; Erlendsdóttir, Helga; Haraldsson, Gunnsteinn; Kristinsson, Karl G; Department of Clinical Microbiology, Landspitali University Hospital, Reykjavik, Iceland Faculty of Medicine, University of Iceland, Reykjavik, Iceland. (Oxford University Press, 2015-08)
      The objective of this study was to investigate the prevalence of pilus islets [pilus islet 1 (PI-1) and pilus islet 2 (PI-2)] in pneumococcal isolates from healthy Icelandic preschool children attending day care centres, prior to the introduction of conjugated pneumococcal vaccine, and the association of the pilus islets with vaccine serotypes and antibiotic resistance.