Show simple item record

dc.contributor.authorKristinsson, J K
dc.contributor.authorGottfredsdottir, M S
dc.contributor.authorStefansson, E
dc.date.accessioned2010-10-07T15:55:41Z
dc.date.available2010-10-07T15:55:41Z
dc.date.issued1997-04
dc.date.submitted2010-10-07
dc.identifier.citationBr J Ophthalmol. 1997, 81(4):274-8en
dc.identifier.issn0007-1161
dc.identifier.pmid9215053
dc.identifier.doi10.1136/bjo.81.4.274
dc.identifier.urihttp://hdl.handle.net/2336/112642
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractAIMS/BACKGROUND: Retinal vessel dilatation is a well known phenomenon in diabetes. In this study, the theory of whether excessive changes in diameter and length of retinal vessels occur in the development of diabetic macular oedema was tested, supporting a hypothesis that the development of diabetic macular oedema may be linked to hydrostatic pressure changes described in Starling's law. METHODS: From fundus photographs of diabetic patients attending a regular eye screening programme, the diameter and segment length of retinal vessels were measured in three retinopathy groups (12 patients each) with diabetic macular oedema (DMO), background retinopathy and no retinopathy, over a period of approximately 4 years, ending at the time of diagnosis of diabetic macular oedema in the DMO group. RESULTS: A statistically significant dilatation and elongation of retinal arterioles, venules, and their macular branches was found before the diagnosis of macular oedema in the DMO group. No significant changes were found in the other two groups. CONCLUSION: It is suggested that Starling's law applies to the formation of oedema in the retina as in other tissues.
dc.language.isoenen
dc.publisherBMJ Pub. Groupen
dc.relation.urlhttp://dx.doi.org/10.1136/bjo.81.4.274en
dc.subject.meshAnalysis of Varianceen
dc.subject.meshCase-Control Studiesen
dc.subject.meshDiabetic Retinopathyen
dc.subject.meshDilatation, Pathologicen
dc.subject.meshDisease Progressionen
dc.subject.meshEdemaen
dc.subject.meshHumansen
dc.subject.meshHydrostatic Pressureen
dc.subject.meshMacula Luteaen
dc.subject.meshMiddle Ageden
dc.subject.meshRetinal Vesselsen
dc.titleRetinal vessel dilatation and elongation precedes diabetic macular oedemaen
dc.typeAnimationen
dc.contributor.departmentDepartment of Ophthalmology, University of Iceland, Landakotsspítali, Reykjavik, Iceland.en
dc.identifier.journalBritish journal of ophthalmologyen
html.description.abstractAIMS/BACKGROUND: Retinal vessel dilatation is a well known phenomenon in diabetes. In this study, the theory of whether excessive changes in diameter and length of retinal vessels occur in the development of diabetic macular oedema was tested, supporting a hypothesis that the development of diabetic macular oedema may be linked to hydrostatic pressure changes described in Starling's law. METHODS: From fundus photographs of diabetic patients attending a regular eye screening programme, the diameter and segment length of retinal vessels were measured in three retinopathy groups (12 patients each) with diabetic macular oedema (DMO), background retinopathy and no retinopathy, over a period of approximately 4 years, ending at the time of diagnosis of diabetic macular oedema in the DMO group. RESULTS: A statistically significant dilatation and elongation of retinal arterioles, venules, and their macular branches was found before the diagnosis of macular oedema in the DMO group. No significant changes were found in the other two groups. CONCLUSION: It is suggested that Starling's law applies to the formation of oedema in the retina as in other tissues.


This item appears in the following Collection(s)

Show simple item record