Glucose tolerance and blood pressure in a population-based cohort study of males and females: the Reykjavik Study
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
CitationJ. Hypertens. 1995, 13(6):581-6
ÚtdrátturOBJECTIVE: To investigate the relationship between fasting and postprandial glucose levels and the risk of hypertension, both cross-sectionally in different age and body mass index (BMI) groups, and prospectively. DESIGN: Long-term prospective health survey in the Reykjavik area, of a large representative population sample of males and females in various age groups, conducted since 1967. METHODS: Values from 8285 males and 9183 females were included in the cross-sectional analysis. The prospective analysis included 2639 males and 2346 females, with two consecutive observations for each individual, with a 3- to 8-year interval. RESULTS: After controlling for year of examination, age, BMI and various other risk factors, we found a strongly significant relationship between the blood glucose level, both fasting and 90 min after an oral glucose load, and risk for hypertension. The strength of the correlation between postprandial glucose value and blood pressure was similar in different age and BMI groups, except for in the males, in whom there was a stronger correlation with diastolic blood pressure with higher BMI. The 90-min glucose level was also predictive for development of hypertension 3-8 years later. The predictive power was somewhat stronger for females. Fasting glucose level was predictive for hypertension only for the females. Concurrent weight gain had a very strong independent explanatory power for development of hypertension. CONCLUSIONS: This study confirms the role of metabolic factors in hypertension. The correlation between impaired glucose tolerance and hypertension was found to be remarkably consistent throughout adult life, for both sexes and all values of BMI. Fasting glucose was predictive of hypertension in the females, and blood glucose at 90 min after the glucose-tolerance test was predictive of future development of hypertension in both sexes.
Lu00FDsingTo access publisher full text version of this article. Please click on the hyperlink in Additional Links field
- Hypertension and overweight associated with hyperinsulinaemia and glucose tolerance: a longitudinal study of the Finnish and Dutch cohorts of the Seven Countries Study.
- Authors: Feskens EJ, Tuomilehto J, Stengård JH, Pekkanen J, Nissinen A, Kromhout D
- Issue date: 1995 Jul
- Hyperinsulinaemia and blood pressure in a general Japanese population: the Hisayama Study.
- Authors: Ohmori S, Kiyohara Y, Kato I, Ohmura T, Iwamoto H, Nakayama K, Nomiyama K, Yoshitake T, Ueda K, Fujishima M
- Issue date: 1994 Oct
- Prevalence of metabolic syndrome among Filipino adults aged 20 years and over.
- Authors: Tanchoco CC, Cruz AJ, Duante CA, Litonjua AD
- Issue date: 2003
- Predictive risk factors for deterioration from normoglycemic state to type 2 diabetes mellitus or impaired glucose tolerance in a Tunisian urban population.
- Authors: Chihaoui M, Kanoun F, Ben Rehaiem B, Ben Brahim S, Ftouhi B, Mekaouar A, Fekih M, Mbazâd A, Zouari B, Ben Khalifa F
- Issue date: 2001 Sep
- Impaired fasting glucose and impaired glucose tolerance do not predict hypertension: a community cohort study.
- Authors: Lee CJ, Lim NK, Kim HC, Ihm SH, Lee HY, Park HY, Park S
- Issue date: 2015 Apr