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dc.contributor.authorArnardottir, Erna Sif
dc.contributor.authorThorleifsdottir, Bjorg
dc.contributor.authorSvanborg, Eva
dc.contributor.authorOlafsson, Isleifur
dc.contributor.authorGislason, Thorarinn
dc.date.accessioned2010-10-25T09:55:08Z
dc.date.available2010-10-25T09:55:08Z
dc.date.issued2010-03-01
dc.date.submitted2010-10-25
dc.identifier.citationJ Sleep Res. 2010, 19(1 Pt 2):122-30en
dc.identifier.issn1365-2869
dc.identifier.pmid19635063
dc.identifier.doi10.1111/j.1365-2869.2009.00743.x
dc.identifier.urihttp://hdl.handle.net/2336/113768
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractThe aim of this study was to investigate sleep-related sweating as a symptom of obstructive sleep apnoea (OSA). Fifteen otherwise healthy male non-smoking patients with untreated moderate-to-severe OSA underwent polysomnography, including measurements of skin and core body temperature and electrodermal activity (EDA) as an objective indicator of sweating. Evening and morning blood pressure was measured as well as catecholamines in nocturnal urine. All measurements were repeated after 3 months on successful continuous positive airway pressure (CPAP) treatment. The untreated OSA subjects had a mean (+/-SD) apnoea-hypopnoea index of 45.3 +/- 3.9 and a mean EDA index during sleep of 131.9 +/- 22.4 events per hour. Patients with higher EDA indices had higher systolic blood pressure in the evening and morning (P = 0.001 and 0.006) and lower rapid eye movement (REM) sleep percentage (P = 0.003). The EDA index decreased significantly to 78.5 +/- 17.7 in the patients on CPAP treatment (P = 0.04). The decrease correlated with lower evening systolic and diastolic blood pressure (P = 0.05 and 0.006) and an increase in REM% (P = 0.02). No relationship was observed between EDA and skin or core body temperature, or to catecholamine levels in urine. OSA patients who experience sleep-related sweating may have increased blood pressure and decreased REM sleep compared with other OSA patients. CPAP treatment appears to lower blood pressure and increase REM sleep to a higher extent in these patients compared with other OSA patients.
dc.language.isoenen
dc.publisherPublished on behalf of the European Sleep Research Society by Blackwell Scientific Publicationsen
dc.relation.urlhttp://dx.doi.org/10.1111/j.1365-2869.2009.00743.xen
dc.subject.meshAbdomenen
dc.subject.meshBody Temperature Regulationen
dc.subject.meshCatecholaminesen
dc.subject.meshContinuous Positive Airway Pressureen
dc.subject.meshGalvanic Skin Responseen
dc.subject.meshHumansen
dc.subject.meshHypertensionen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshNasal Obstructionen
dc.subject.meshPlethysmographyen
dc.subject.meshPolysomnographyen
dc.subject.meshSeverity of Illness Indexen
dc.subject.meshSleepen
dc.subject.meshSleep Apnea, Obstructiveen
dc.subject.meshSleep, REMen
dc.subject.meshSweatingen
dc.subject.meshThoraxen
dc.titleSleep-related sweating in obstructive sleep apnoea: association with sleep stages and blood pressureen
dc.typeArticleen
dc.contributor.departmentDepartment of Respiratory Medicine and Sleep, Landspitali University Hospital, Reykjavik, Iceland.en
dc.identifier.journalJournal of sleep researchen
html.description.abstractThe aim of this study was to investigate sleep-related sweating as a symptom of obstructive sleep apnoea (OSA). Fifteen otherwise healthy male non-smoking patients with untreated moderate-to-severe OSA underwent polysomnography, including measurements of skin and core body temperature and electrodermal activity (EDA) as an objective indicator of sweating. Evening and morning blood pressure was measured as well as catecholamines in nocturnal urine. All measurements were repeated after 3 months on successful continuous positive airway pressure (CPAP) treatment. The untreated OSA subjects had a mean (+/-SD) apnoea-hypopnoea index of 45.3 +/- 3.9 and a mean EDA index during sleep of 131.9 +/- 22.4 events per hour. Patients with higher EDA indices had higher systolic blood pressure in the evening and morning (P = 0.001 and 0.006) and lower rapid eye movement (REM) sleep percentage (P = 0.003). The EDA index decreased significantly to 78.5 +/- 17.7 in the patients on CPAP treatment (P = 0.04). The decrease correlated with lower evening systolic and diastolic blood pressure (P = 0.05 and 0.006) and an increase in REM% (P = 0.02). No relationship was observed between EDA and skin or core body temperature, or to catecholamine levels in urine. OSA patients who experience sleep-related sweating may have increased blood pressure and decreased REM sleep compared with other OSA patients. CPAP treatment appears to lower blood pressure and increase REM sleep to a higher extent in these patients compared with other OSA patients.


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