Reactivation of rheumatoid arthritis and development of leukocytoclastic vasculitis in a patient receiving granulocyte colony-stimulating factor for Felty's syndrome
Name:
Publisher version
View Source
Access full-text PDFOpen Access
View Source
Check access options
Check access options
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Issue Date
1995-06-01
Metadata
Show full item recordCitation
Am. J. Med. 1995, 98(6):589-91Abstract
Patients with Felty’s syndrome, the combination of rheumatoid arthritis, splenomegaly, and neutropenia, have increased susceptibility to bacterial infections. The patients are usually b-elated with steroids or splenectomy. Granulocyte-macrophage colony-stimulating factor (GM-CSF)1-6 and granulocyte colony-stimulating factor (G-CSF)5g have been reported to correct the neutropenia of Felty’s syndrome. Both drugs have also been reported to exacerbate inflammatory diseases such as vasculitis,loJ1 but to our knowledge, only GM-CSF has been reported to cause arthritis flare-up in palzients with Felty’s syndrome. 1,12 This report describes reactivation of previously inactive arthritis and development of leukocytoclastic vasculitis in a patient with Felty’s syndrome treated with G-CSF.Description
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldAdditional Links
http://dx.doi.org/10.1016/S0002-9343(99)80019-9ae974a485f413a2113503eed53cd6c53
10.1016/S0002-9343(99)80019-9
Scopus Count
Collections
Related articles
- Use of colony-stimulating factors in the treatment of neutropenia associated with collagen vascular disease.
- Authors: Starkebaum G
- Issue date: 1997 May
- Flare of arthritis with successful treatment of Felty's syndrome with granulocyte colony stimulating factor (GCSF).
- Authors: Hayat SQ, Hearth-Holmes M, Wolf RE
- Issue date: 1995 Mar
- Felty's syndrome treated with rhG-CSF associated with flare of arthritis and skin rash.
- Authors: McMullin MF, Finch MB
- Issue date: 1995 Mar
- Granulocyte-colony stimulating factor corrects granulocytopenia in Felty's syndrome.
- Authors: Ito T, Miyairi Y, Kuwabara T, Dan K, Nomura T
- Issue date: 1992 Aug
- Vasculitis complicating granulocyte colony stimulating factor treatment of leukopenia and infection in Felty's syndrome.
- Authors: Farhey YD, Herman JH
- Issue date: 1995 Jun