Induced hypothermia in comatose survivors of asphyxia: a case series of 14 consecutive cases
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
CitationActa Anaesthesiol Scand. 2010, 54(7):821-6
AbstractBACKGROUND: Induced hypothermia is widely used for comatose survivors of cardiac arrest. Other causes of hypoxic brain injury carry a poor prognosis when treated using traditional methods. At our hospital, hypothermia has also been used for the management of all comatose survivors of asphyxiation. The aim of the present study was to report the results of the management of these patients. METHODS: Hospital charts of all patients admitted unconscious after asphyxiation during a 7-year period were reviewed. This included patients after hanging, drowning, carbon monoxide intoxication and other gas intoxications. In all patients, hypothermia with a target temperature of 32-34 degrees C was induced with external or intravascular cooling for 24 h. The primary outcome was neurologic function at discharge. RESULTS: Fourteen male patients were treated with hypothermia, eight after hanging, three after drowning, two after carbon monoxide intoxication and one after methane intoxication. All were deeply comatose (Glasgow Coma Score 3-5) on arrival to hospital. Nine had been resuscitated from cardiac arrest. There were nine survivors (65%), all with good neurological recovery (Cerebral Performance Category 1-2). Four out of five non-survivors showed cerebral edema already on arrival computed tomographic (CT) scan while none of the nine survivors did. CONCLUSIONS: The results of this study suggest that an early abnormal CT scan of the brain in patients resuscitated after asphyxiation carries an adverse prognosis. The favorable outcome of the patients in the present study suggests that a randomized clinical trial on the use of induced hypothermia in patients exposed to severe asphyxia might be warranted.
DescriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links field
- Beneficial response to mild therapeutic hypothermia for comatose survivors of near-hanging.
- Authors: Jehle D, Meyer M, Gemme S
- Issue date: 2010 Mar
- Therapeutic hypothermia for a comatose survivor of near-hanging.
- Authors: Sadaka F, Wood MP, Cox M
- Issue date: 2012 Jan
- Bradycardia during therapeutic hypothermia is associated with good neurologic outcome in comatose survivors of out-of-hospital cardiac arrest.
- Authors: Stær-Jensen H, Sunde K, Olasveengen TM, Jacobsen D, Drægni T, Nakstad ER, Eritsland J, Andersen GØ
- Issue date: 2014 Nov
- Therapeutic hypothermia for comatose survivors after near-hanging-a retrospective analysis.
- Authors: Borgquist O, Friberg H
- Issue date: 2009 Feb
- Neurologic outcome of comatose survivors after hanging: a retrospective multicenter study.
- Authors: Kim MJ, Yoon YS, Park JM, Cho J, Lim H, Kang H, Kim HJ, Kim SW, Lee KR, Kim GB, Park JS, Lee HS, Chung SP
- Issue date: 2016 Aug