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Vioxx - víti til varnaðar? [ritstjórnargrein]

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Authors
Sigurður Guðmundsson
Issue Date
2004-11-01

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Other Titles
Vioxx - What can we learn? [editorial]
Citation
Læknablaðið 2004, 90(11):735-6
Abstract
Þann 30. september síðastliðinn bárust þau óvenjulegu tíðindi að framleiðandi rófecoxíbs (Vioxx®), lyfja­fyrirtækið Merck, Sharp & Dohme hafi tekið lyfið af markaði vegna nýrra upplýsinga um aukna áhættu af völdum blóðsegamyndunar, kransæða­stíflu og heila­blóðfalla. Rófecoxíb er í flokki sýkló-oxýgenasa 2 hemla (coxíb) og var hið fyrsta þeirra á markaði. Þessi lyfjaflokkur kom fram fyrir fimm árum og fékk rófecoxíb markaðsleyfi á Íslandi í mars árið 2000. Lyfið naut strax mikillar hylli hér á landi sem annars staðar, enda var gengið fram af krafti við markaðssetningu lyfsins. Söluverðmæti lyfjaflokksins hér á landi árið 2003 var rúmlega 250 milljónir. Hélt rófecoxíb nokkuð öruggri forystu þótt celecoxíb (Celebra) hafi sótt á undanfarin tvö ár. Söluverðmæti lyfjaflokksins fyrstu sex mánuði ársins 2004 mun vera um 120 milljónir. Íslenskir læknar, og reyndar sjúk­lingar líka, tóku því mjög vel við sér í þessu efni. Við vorum reyndar ekki ein á báti þar, en stóðum mjög framarlega í flokki.
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