Effects of age and sex on the strength and cortical thickness of the femoral neck.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
AuthorsCarpenter, R D
Jonsson, B Y
Harris, T B
Lang, T F
MetadataShow full item record
CitationBone. 2011, 48(4):741-7
AbstractA group of 48 men (22 aged 65-75 years, 26 aged 80-90 years) and 59 women (32 aged 65-75 years, 27 aged 80-90 years) were enrolled in the Age, Gene/Environment Susceptibility-Reykjavik study and imaged with in vivo volumetric Quantitative Computed Tomography (QCT) to investigate the effects of age and sex on femoral neck structure and strength. Femoral neck cross-sectional moment of inertia for bending directions near those of standing and walking (I(AP)), bending strength (M(y)), and axial compressive strength (F(y)) were computed at the location of minimum cross-sectional area (minCSA). Local cortical thickness was computed in the inferior femoral neck based on density profiles extending through the cortex of the minCSA femoral neck section. Multivariate models accounting for height, weight, and age group (younger or older) showed that men had a 46% higher M(y) and a 23% higher F(y) than women, while women had a 13% thicker inferior cortex than men. Cortical thickness in the inferoposterior region of the femoral neck was significantly related to bending and axial strength after adjusting for overall volumetric bone mineral density. Both minCSA and I(AP) were higher in the older, gender-pooled age group, but F(y) and M(y) did not differ between the two age groups. The results suggest that age-related expansion of the femoral neck primarily occurs in the superior and inferior directions and helps maintain homeostasis of femoral neck stiffness and strength. The higher bending strength of the male femoral neck may partly explain why elderly men have a lower risk of hip fracture than elderly women.
DescriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links field
- New QCT analysis approach shows the importance of fall orientation on femoral neck strength.
- Authors: Carpenter RD, Beaupré GS, Lang TF, Orwoll ES, Carter DR, Osteoporotic Fractures in Men (MrOS) Study Group.
- Issue date: 2005 Sep
- Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging.
- Authors: Duan Y, Beck TJ, Wang XF, Seeman E
- Issue date: 2003 Oct
- Varying contributions of growth and ageing to racial and sex differences in femoral neck structure and strength in old age.
- Authors: Wang XF, Duan Y, Beck TJ, Seeman E
- Issue date: 2005 Jun
- Increasing sex difference in bone strength in old age: The Age, Gene/Environment Susceptibility-Reykjavik study (AGES-REYKJAVIK).
- Authors: Sigurdsson G, Aspelund T, Chang M, Jonsdottir B, Sigurdsson S, Eiriksdottir G, Gudmundsson A, Harris TB, Gudnason V, Lang TF
- Issue date: 2006 Sep
- Similarities and differences between sexes in regional loss of cortical and trabecular bone in the mid-femoral neck: the AGES-Reykjavik longitudinal study.
- Authors: Johannesdottir F, Aspelund T, Reeve J, Poole KE, Sigurdsson S, Harris TB, Gudnason VG, Sigurdsson G
- Issue date: 2013 Oct