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dc.contributor.authorRona, Roberto J
dc.contributor.authorKeil, Thomas
dc.contributor.authorSummers, Colin
dc.contributor.authorGislason, David
dc.contributor.authorZuidmeer, Laurian
dc.contributor.authorSodergren, Eva
dc.contributor.authorSigurdardottir, Sigurveig T
dc.contributor.authorLindner, Titia
dc.contributor.authorGoldhahn, Klaus
dc.contributor.authorDahlstrom, Jorgen
dc.contributor.authorMcBride, Doreen
dc.contributor.authorMadsen, Charlotte
dc.date.accessioned2007-11-02T11:49:30Z
dc.date.available2007-11-02T11:49:30Z
dc.date.issued2007-09-01
dc.date.submitted2007-11-02
dc.identifier.citationJ. Allergy Clin. Immunol. 2007, 120(3):638-46en
dc.identifier.issn0091-6749
dc.identifier.pmid17628647
dc.identifier.doi10.1016/j.jaci.2007.05.026
dc.identifier.urihttp://hdl.handle.net/2336/14393
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Link fielden
dc.description.abstractBACKGROUND: There is uncertainty about the prevalence of food allergy in communities. OBJECTIVE: To assess the prevalence of food allergy by performing a meta-analysis according to the method of assessment used. METHODS: The foods assessed were cow's milk, hen's egg, peanut, fish, shellfish, and an overall estimate of food allergy. We summarized the information in 5 categories: self-reported symptoms, specific IgE positive, specific skin prick test positive, symptoms combined with sensitization, and food challenge studies. We systematically searched MEDLINE and EMBASE for publications since 1990. The meta-analysis included only original studies. They were stratified by age groups: infant/preschool, school children, and adults. RESULTS: A total of 934 articles were identified, but only 51 were considered appropriate for inclusion. The prevalence of self-reported food allergy was very high compared with objective measures. There was marked heterogeneity between studies regardless of type of assessment or food item considered, and in most analyses this persisted after age stratification. Self-reported prevalence of food allergy varied from 1.2% to 17% for milk, 0.2% to 7% for egg, 0% to 2% for peanuts and fish, 0% to 10% for shellfish, and 3% to 35% for any food. CONCLUSION: There is a marked heterogeneity in the prevalence of food allergy that could be a result of differences in study design or methodology, or differences between populations. CLINICAL IMPLICATIONS: We recommend that measurements be made by using standardized methods, if possible food challenge. We need to be cautious in estimates of prevalence based only on self-reported food allergy.
dc.language.isoenen
dc.publisherMosbyen
dc.relation.urlhttp://www.sciencedirect.com/science/article/B6WH4-4P5RKN3-2/2/809234e70bab204b98f18e37b7b26d18en
dc.subject.meshPubMed - in processen
dc.subject.meshPrevalenceen
dc.subject.meshFood Hypersensitivityen
dc.subject.meshEgg Hypersensitivityen
dc.titleThe prevalence of food allergy: a meta-analysis.en
dc.typeArticleen
dc.format.digYES
html.description.abstractBACKGROUND: There is uncertainty about the prevalence of food allergy in communities. OBJECTIVE: To assess the prevalence of food allergy by performing a meta-analysis according to the method of assessment used. METHODS: The foods assessed were cow's milk, hen's egg, peanut, fish, shellfish, and an overall estimate of food allergy. We summarized the information in 5 categories: self-reported symptoms, specific IgE positive, specific skin prick test positive, symptoms combined with sensitization, and food challenge studies. We systematically searched MEDLINE and EMBASE for publications since 1990. The meta-analysis included only original studies. They were stratified by age groups: infant/preschool, school children, and adults. RESULTS: A total of 934 articles were identified, but only 51 were considered appropriate for inclusion. The prevalence of self-reported food allergy was very high compared with objective measures. There was marked heterogeneity between studies regardless of type of assessment or food item considered, and in most analyses this persisted after age stratification. Self-reported prevalence of food allergy varied from 1.2% to 17% for milk, 0.2% to 7% for egg, 0% to 2% for peanuts and fish, 0% to 10% for shellfish, and 3% to 35% for any food. CONCLUSION: There is a marked heterogeneity in the prevalence of food allergy that could be a result of differences in study design or methodology, or differences between populations. CLINICAL IMPLICATIONS: We recommend that measurements be made by using standardized methods, if possible food challenge. We need to be cautious in estimates of prevalence based only on self-reported food allergy.


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