Estimation of 10-year risk of fatal cardiovascular disease and coronary heart disease in Iceland with results comparable with those of the Systematic Coronary Risk Evaluation project.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
CitationEur J Cardiovasc Prev Rehabil 2007, 14(6):761-8
AbstractBACKGROUND: No data are available on the comparison between an absolute 10-year risk of fatal cardiovascular disease (CVD) and coronary heart disease (CHD) morbidity using the risk assessments of the Systematic Coronary Risk Evaluation (SCORE) project. DESIGN: Data from the prospective Reykjavik Study of 15 782 patients were used to estimate the 10-year risk of fatal CVD and CHD morbidity in Iceland. METHODS: Survival to fatal CVD event was defined as in the SCORE project. Survival to CHD morbidity was defined as having a myocardial infarction, coronary artery bypass graft, or angioplasty. The statistical methodology of SCORE was used. RESULTS: Relative risk in Iceland was comparable with SCORE results but baseline risk was similar to the low-risk version of SCORE, which contradicted previous suggestions for the countries of northern Europe. Correlation between absolute risk of CHD morbidity and risk for fatal CVD was high (r=0.96), resulting in similar ranking of individuals by risk and discriminatory capacity. This is the first published comparison between total fatal CVD risk and CHD morbidity in a population-based cohort using the current risk assessment guidelines of the European Societies on Coronary Prevention. CONCLUSIONS: Risk for fatal CVD in Iceland has the same characteristics as those in a European nation with results varying in accordance with the SCORE project. The risk estimate to be used, CHD morbidity or fatal CVD, is a choice of clinical preference. The data, however, suggest that 5% high-risk threshold of fatal CVD corresponds to a 12% CHD-morbidity risk, which is a significant change from the conventional reference value of 20%.
DescriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Link field
- Predicted and observed cardiovascular disease in South Asians: application of FINRISK, Framingham and SCORE models to Newcastle Heart Project data.
- Authors: Bhopal R, Fischbacher C, Vartiainen E, Unwin N, White M, Alberti G
- Issue date: 2005 Mar
- Cardiovascular risk estimation by professionally active cardiovascular nurses: results from the Basel 2005 Nurses Cohort.
- Authors: Scholte op Reimer WJ, Moons P, De Geest S, Fridlund B, Heikkilä J, Jaarsma T, Lenzen M, Martensson J, Norekvål TM, Smith K, Stewart S, Strömberg A, Thompson DR, Basel 2005 Nurses Cohort.
- Issue date: 2006 Dec
- Independent impact of gout on mortality and risk for coronary heart disease.
- Authors: Choi HK, Curhan G
- Issue date: 2007 Aug 21
- The impact of birth weight on coronary heart disease morbidity and mortality in a birth cohort followed up for 85 years: a population-based study of men born in 1913.
- Authors: Eriksson M, Wallander MA, Krakau I, Wedel H, Svärdsudd K
- Issue date: 2004 Dec
- Validity of the Framingham point scores in the elderly: results from the Rotterdam study.
- Authors: Koller MT, Steyerberg EW, Wolbers M, Stijnen T, Bucher HC, Hunink MG, Witteman JC
- Issue date: 2007 Jul