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dc.contributor.authorBlondal, Renata
dc.contributor.authorSturludottir, Margret Kara
dc.contributor.authorHardarson, Sveinn Hakon
dc.contributor.authorHalldorsson, Gisli Hreinn
dc.contributor.authorStefánsson, Einar
dc.date.accessioned2012-05-14T09:34:47Z
dc.date.available2012-05-14T09:34:47Z
dc.date.issued2011-09
dc.date.submitted2012-05-14
dc.identifier.citationGraefes Arch. Clin. Exp. Ophthalmol. 2011, 249(9):1311-7en_GB
dc.identifier.issn1435-702X
dc.identifier.pmid21499769
dc.identifier.doi10.1007/s00417-011-1680-2
dc.identifier.urihttp://hdl.handle.net/2336/223498
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links field.en_GB
dc.description.abstractBACKGROUND: The purpose of this study was to test the reliability of vessel diameter measurements with a newly developed retinal oximeter. METHODS: Twelve healthy individuals participated in the study. Retinal images were taken with the Oxymap Retinal Oximeter. Diameters of retinal vessels were measured automatically with the Oxymap Analyzer software. Repeated measurements on the same vessel segments were compared. The automatic measurements were also compared with semi-automatic measurements with a plug-in for the ImageJ software. RESULTS: Variance coefficient (standard deviation/mean) from the repeatability test was 2.8 and 4.0% for first- and second-degree venules and 3.5 and 5.4% for first- and second-degree arterioles, respectively. ImageJ measured larger mean diameters than Oxymap Analyzer in all cases. Means of differences were 5.1 ± 2.2, 2.9 ± 1.3, and 2.7 ± 1.6 pixels for first-, second-, and third-degree venules and 3.1 ± 1.2, 2.7 ± 0.9, and 2.9 ± 1.4 pixels for first-, second-, and third-degree arterioles. CONCLUSIONS: Vessel diameter measurements with the oximeter are repeatable and comparison with an established method demonstrates a relatively stable offset where the standard deviation of the difference is rather small. Different definitions of vessel borders may be the cause of this difference.
dc.language.isoenen
dc.publisherSpringer-Verlagen_GB
dc.relation.urlhttp://dx.doi.org/10.1007/s00417-011-1680-2en_GB
dc.rightsArchived with thanks to Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologieen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAlgorithmsen_GB
dc.subject.meshArteriolesen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshImage Processing, Computer-Assisteden_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshOptic Disken_GB
dc.subject.meshOximetryen_GB
dc.subject.meshOxygenen_GB
dc.subject.meshReproducibility of Resultsen_GB
dc.subject.meshRetinal Arteryen_GB
dc.subject.meshRetinal Veinen_GB
dc.subject.meshRetinal Vesselsen_GB
dc.subject.meshSoftwareen_GB
dc.subject.meshVenulesen_GB
dc.titleReliability of vessel diameter measurements with a retinal oximeter.en
dc.typeArticleen
dc.contributor.departmentOxymap ehf.; Landspitali The National University Hospital, Reykjavík, Iceland.en_GB
dc.identifier.journalGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologieen_GB
html.description.abstractBACKGROUND: The purpose of this study was to test the reliability of vessel diameter measurements with a newly developed retinal oximeter. METHODS: Twelve healthy individuals participated in the study. Retinal images were taken with the Oxymap Retinal Oximeter. Diameters of retinal vessels were measured automatically with the Oxymap Analyzer software. Repeated measurements on the same vessel segments were compared. The automatic measurements were also compared with semi-automatic measurements with a plug-in for the ImageJ software. RESULTS: Variance coefficient (standard deviation/mean) from the repeatability test was 2.8 and 4.0% for first- and second-degree venules and 3.5 and 5.4% for first- and second-degree arterioles, respectively. ImageJ measured larger mean diameters than Oxymap Analyzer in all cases. Means of differences were 5.1 ± 2.2, 2.9 ± 1.3, and 2.7 ± 1.6 pixels for first-, second-, and third-degree venules and 3.1 ± 1.2, 2.7 ± 0.9, and 2.9 ± 1.4 pixels for first-, second-, and third-degree arterioles. CONCLUSIONS: Vessel diameter measurements with the oximeter are repeatable and comparison with an established method demonstrates a relatively stable offset where the standard deviation of the difference is rather small. Different definitions of vessel borders may be the cause of this difference.


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