High constant incidence rates of second primary cancers of the head and neck: a pooled analysis of 13 cancer registries.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Tonita, Jon M
Jonasson, Jon G
Kliewer, Erich V
Olsen, Jorgen H
Brewster, David H
La Vecchia, Carlo
MetadataShow full item record
CitationInt. J. Cancer. 2011, 129(1):173-9
AbstractScanty data are available on the incidence (i.e., the absolute risk) of second cancers of the head and neck (HN) and its pattern with age. We investigated this issue using data from a multicentric study of 13 population-based cancer registries from Europe, Canada, Australia and Singapore for the years 1943-2000. A total of 99,257 patients had a first primary HN cancer (15,985 tongue, 22,378 mouth, 20,758 pharyngeal, and 40,190 laryngeal cancer), contributing to 489,855 person-years of follow-up. A total of 1,294 of the patients (1.3%) were diagnosed with second HN cancers (342 tongue, 345 mouth, 418 pharynx and 189 larynx). Male incidence rates of first HN cancer steeply increased from 0.68/100,000 at age 30-34 to 46.2/100,000 at age 70-74, and leveled off at older age; female incidence increased from 0.50/100,000 at age 30-34 to 16.5/100,000 at age 80-84. However, age-specific incidence of second HN cancers after a first HN cancer in men was around 200-300/100,000 between age 40-44 and age 70-74 and tended to decline at subsequent ages (150/100,000 at age 80-84); in women, incidence of second HN cancers was around 200-300/100,000 between age 45-49 and 80-84. The patterns of age-specific incidence were consistent for different subsites of second HN cancer and sexes; moreover, they were similar for age-specific incidence of first primary HN cancer in patients who subsequently developed a second HN cancer. The incidence of second HN cancers does not increase with age, but remains constant, or if anything, decreases with advancing age.
DescriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links field.
RightsArchived with thanks to International journal of cancer. Journal international du cancer
- Risk of second primary cancer among patients with head and neck cancers: A pooled analysis of 13 cancer registries.
- Authors: Chuang SC, Scelo G, Tonita JM, Tamaro S, Jonasson JG, Kliewer EV, Hemminki K, Weiderpass E, Pukkala E, Tracey E, Friis S, Pompe-Kirn V, Brewster DH, Martos C, Chia KS, Boffetta P, Brennan P, Hashibe M
- Issue date: 2008 Nov 15
- Italian cancer figures, report 2013: Multiple tumours.
- Authors: AIRTUM Working Group.
- Issue date: 2013 Jul-Oct
- Risk of second primary cancer among esophageal cancer patients: a pooled analysis of 13 cancer registries.
- Authors: Chuang SC, Hashibe M, Scelo G, Brewster DH, Pukkala E, Friis S, Tracey E, Weiderpass E, Hemminki K, Tamaro S, Chia KS, Pompe-Kirn V, Kliewer EV, Tonita JM, Martos C, Jonasson JG, Dresler CM, Boffetta P, Brennan P
- Issue date: 2008 Jun
- Trends over three decades of the risk of second primary cancer among patients with head and neck cancer.
- Authors: Jégu J, Binder-Foucard F, Borel C, Velten M
- Issue date: 2013 Jan
- Second primary cancers in patients with nasopharyngeal carcinoma: a pooled analysis of 13 cancer registries.
- Authors: Scélo G, Boffetta P, Corbex M, Chia KS, Hemminki K, Friis S, Pukkala E, Weiderpass E, McBride ML, Tracey E, Brewster DH, Pompe-Kirn V, Kliewer EV, Tonita JM, Martos C, Jonasson JG, Brennan P
- Issue date: 2007 Apr