Increasing incidence of late-onset neonatal invasive group B streptococcal infections in Iceland.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
AuthorsÓladóttir, Guđrún Lilja
Björnsdóttir, Erla Soffía
Kristinsson, Karl G
MetadataShow full item record
CitationPediatr. Infect. Dis. J. 2011, 30 (8):661-3
AbstractBACKGROUND: Group B streptococci (GBS) may cause life-threatening invasive infections in infants. The incidence of these infections has been increasing during the last decades. The aim of the study was to determine the epidemiology of neonatal GBS infections to be able to implement therapeutic and preventive measures more effectively. METHODS: A retrospective case study was conducted in Iceland that included all neonates with positive GBS cultures from blood or cerebrospinal fluid during the period 1975 to 2006. Serotyping of all available GBS isolates was performed. RESULTS: A total of 87 children with 89 infections were included in the study. In all, 53 infants had early-onset (EO) GBS infections (occurring <7 days after birth) and 34 had late-onset (LO) infections (occurring on days 7-90). EO infections increased during the first 3 quartiles of the study period but decreased during the last quartile. LO infections increased throughout the entire study period. GBS was cultured from cerebrospinal fluid in 21 patients; 9 with EO and 12 with LO infections. Premature infants comprised 15 with EO and 14 with LO infections. Eight children died of GBS infection, 7 with EO and 1 with LO infections; no correlation with serotypes was found. Serotype III was most common for both EO (34%) and LO infections (62%). CONCLUSION: The number of GBS infections increased during the study period. The decrease in EO infections in recent years could be attributed to intrapartum antibiotic treatment. The increasing number of LO infections is a concern.
DescriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links field.
RightsArchived with thanks to The Pediatric infectious disease journal
- Distribution of genotypes and antibiotic resistance genes among invasive Streptococcus agalactiae (group B streptococcus) isolates from Australasian patients belonging to different age groups.
- Authors: Zhao Z, Kong F, Zeng X, Gidding HF, Morgan J, Gilbert GL
- Issue date: 2008 Mar
- Early-onset group B streptococcal disease in the era of maternal screening.
- Authors: Puopolo KM, Madoff LC, Eichenwald EC
- Issue date: 2005 May
- Serotype IV and invasive group B Streptococcus disease in neonates, Minnesota, USA, 2000-2010.
- Authors: Ferrieri P, Lynfield R, Creti R, Flores AE
- Issue date: 2013 Apr
- Neonatal group B streptococcal disease in Finland: a ten-year nationwide study.
- Authors: Kalliola S, Vuopio-Varkila J, Takala AK, Eskola J
- Issue date: 1999 Sep