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dc.contributor.authorHelgadottir, Solveig
dc.contributor.authorSigurdsson, Martin I
dc.contributor.authorIngvarsdottir, Inga L
dc.contributor.authorArnar, David O
dc.contributor.authorGudbjartsson, Tomas
dc.date.accessioned2013-08-23T13:54:03Z
dc.date.available2013-08-23T13:54:03Z
dc.date.issued2012
dc.date.submitted2013-08-23
dc.identifier.citationJ Cardiothorac Surg 2012, 7:87en_GB
dc.identifier.issn1749-8090
dc.identifier.pmid22992266
dc.identifier.doi10.1186/1749-8090-7-87
dc.identifier.urihttp://hdl.handle.net/2336/299649
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links field.en_GB
dc.description.abstractWe studied potential risk factors for postoperative atrial fibrillation (POAF) in a large cohort of patients who underwent open-heart surgery, evaluating short- and long-term outcome, and we developed a risk-assessment model of POAF. A retrospective study of 744 patients without prior history of AF who underwent CABG (n = 513), OPCAB (n = 207), and/or AVR (n = 156) at Landspitali Hospital in 2002-2006. Logistic regression analysis was used to study risk factors for POAF, comparing patients with and without POAF. The rate of POAF was 44%, and was higher following AVR (74%) than after CABG (44%) or OPCAB (35%). In general, patients with POAF were significantly older, were more often female, were less likely to be smokers, had a lower EF, and had a higher EuroSCORE. The use of antiarrythmics was similar in the groups but patients who experienced POAF were less likely to be taking statins. POAF patients also had longer hospital stay, higher rates of complications, and operative mortality (5% vs. 0.7%). In multivariate analysis, AVR (OR 4.4), a preoperative history of cardiac failure (OR 1.8), higher EuroSCORE (OR 1.1), and advanced age (OR 1.1) were independent prognostic factors for POAF. Overall five-year survival was 83% and 93% for patients with and without POAF (p <0.001). POAF was detected in 44% of patients, which is high compared to other studies. In the future, our assessment score will hopefully be of use in identifying patients at high risk of POAF and lower complications related to POAF.
dc.description.sponsorshipLandspitali University Research Fund University of Iceland Research Fund Helga Jónsdottir and Sigurlidi Kristjansson Memorial Funden_GB
dc.language.isoenen
dc.publisherBioMed Centralen_GB
dc.relation.urlhttp://dx.doi.org/10.1186/1749-8090-7-87en_GB
dc.relation.urlhttp://www.cardiothoracicsurgery.org/content/7/1/87en_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515503/en_GB
dc.rightsArchived with thanks to Journal of cardiothoracic surgeryen_GB
dc.subject.meshAgeden_GB
dc.subject.meshAtrial Fibrillationen_GB
dc.subject.meshCoronary Artery Bypassen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHeart Valve Prosthesis Implantationen_GB
dc.subject.meshHumansen_GB
dc.subject.meshIcelanden_GB
dc.subject.meshKaplan-Meier Estimateen_GB
dc.subject.meshLogistic Modelsen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshPostoperative Complicationsen_GB
dc.subject.meshRetrospective Studiesen_GB
dc.subject.meshRisk Factorsen_GB
dc.titleAtrial fibrillation following cardiac surgery: risk analysis and long-term survival.en
dc.typeArticleen
dc.contributor.departmentDepartments of Cardiothoracic Surgery, University of Iceland, Reykjavik, Iceland.en_GB
dc.identifier.journalJournal of cardiothoracic surgeryen_GB
dc.rights.accessOpen Access - Opinn aðganguren
html.description.abstractWe studied potential risk factors for postoperative atrial fibrillation (POAF) in a large cohort of patients who underwent open-heart surgery, evaluating short- and long-term outcome, and we developed a risk-assessment model of POAF. A retrospective study of 744 patients without prior history of AF who underwent CABG (n = 513), OPCAB (n = 207), and/or AVR (n = 156) at Landspitali Hospital in 2002-2006. Logistic regression analysis was used to study risk factors for POAF, comparing patients with and without POAF. The rate of POAF was 44%, and was higher following AVR (74%) than after CABG (44%) or OPCAB (35%). In general, patients with POAF were significantly older, were more often female, were less likely to be smokers, had a lower EF, and had a higher EuroSCORE. The use of antiarrythmics was similar in the groups but patients who experienced POAF were less likely to be taking statins. POAF patients also had longer hospital stay, higher rates of complications, and operative mortality (5% vs. 0.7%). In multivariate analysis, AVR (OR 4.4), a preoperative history of cardiac failure (OR 1.8), higher EuroSCORE (OR 1.1), and advanced age (OR 1.1) were independent prognostic factors for POAF. Overall five-year survival was 83% and 93% for patients with and without POAF (p <0.001). POAF was detected in 44% of patients, which is high compared to other studies. In the future, our assessment score will hopefully be of use in identifying patients at high risk of POAF and lower complications related to POAF.


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