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dc.contributor.authorSveinsson, Olafur
dc.contributor.authorHalldórsson, Sigurður
dc.contributor.authorOlafsson, Elias
dc.date.accessioned2013-09-19T13:48:32Z
dc.date.available2013-09-19T13:48:32Z
dc.date.issued2012
dc.date.submitted2013-09-19
dc.identifier.citationEur. Neurol. 2012, 68(1):48-51en_GB
dc.identifier.issn1421-9913
dc.identifier.pmid22722209
dc.identifier.doi10.1159/000337680
dc.identifier.urihttp://hdl.handle.net/2336/301913
dc.descriptionTo access publisher's full text version of this article. Please click on the hyperlink in Additional Links field.en_GB
dc.description.abstractHuntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by involuntary movements and psychiatric disturbances, found worldwide, with a variable prevalence. The purpose of this study was to determine the history of HD in Iceland and determine the prevalence and incidence of HD. Clinical information was obtained from general, neurologic, and psychiatric hospitals, practicing neurologists, general practitioners, and family members of affected individuals. Twenty-seven individuals were identified with typical symptoms of HD from the 1850s to 2007. All but one sporadic case are descendants of a husband and wife living in the early and mid-19th century. The point prevalence of HD in Iceland is 1.0 per 100,000 individuals. The prevalence of HD in Iceland is markedly lower than in the neighboring countries (Norway and the British Isles), where Icelanders originate from
dc.description.sponsorshipIceland's University research funden_GB
dc.language.isoenen
dc.publisherKargeren_GB
dc.relation.urlhttp://www.karger.com/Article/Pdf/337680en_GB
dc.relation.urlhttp://dx.doi.org/10.1159/000337680en_GB
dc.rightsArchived with thanks to European neurologyen_GB
dc.subject.meshAdulten_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHistory, 16th Centuryen_GB
dc.subject.meshHumansen_GB
dc.subject.meshHuntington Diseaseen_GB
dc.subject.meshIcelanden_GB
dc.subject.meshIncidenceen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshPrevalenceen_GB
dc.subject.meshYoung Adulten_GB
dc.titleAn unusually low prevalence of Huntington's disease in Iceland.en
dc.typeArticleen
dc.contributor.departmentDepartment of Neurology, Landspitali University Hospital, Reykjavik, Icelanden_GB
dc.identifier.journalEuropean neurologyen_GB
dc.rights.accessNational Consortium - Landsaðganguren
html.description.abstractHuntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by involuntary movements and psychiatric disturbances, found worldwide, with a variable prevalence. The purpose of this study was to determine the history of HD in Iceland and determine the prevalence and incidence of HD. Clinical information was obtained from general, neurologic, and psychiatric hospitals, practicing neurologists, general practitioners, and family members of affected individuals. Twenty-seven individuals were identified with typical symptoms of HD from the 1850s to 2007. All but one sporadic case are descendants of a husband and wife living in the early and mid-19th century. The point prevalence of HD in Iceland is 1.0 per 100,000 individuals. The prevalence of HD in Iceland is markedly lower than in the neighboring countries (Norway and the British Isles), where Icelanders originate from


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